AUTHOR=de Oliviera Nascimento Laura , Massari Paola , Wetzler Lee M.

TITLE=The Role of TLR2 in Infection and Immunity

JOURNAL=Frontiers in Immunology

VOLUME=Volume 3 - 2012

YEAR=2012

URL=https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2012.00079

DOI=10.3389/fimmu.2012.00079

ISSN=1664-3224

ABSTRACT=	TLR2 forms heterodimers with TLR1 and 6 and these heterodimers are recognition molecules for a panoply of pathogens, allowing for significant innate immune responses that accounts for protection from these pathogens and immune sequelae related to infection with these pathogens.  These pathogens include bacteria, viruses, fungi and parasites.  This review will discuss the current state of the art regarding TLR2 recognition of pathogen associated molecular patterns (PAMPS) and the relationship of the responses induced by such recognition to immune protection and pathology.