AUTHOR=Tang Xianfang , Cai Lijun , Meng Yajie , Xu JunLin , Lu Changcheng , Yang Jialiang TITLE=Indicator Regularized Non-Negative Matrix Factorization Method-Based Drug Repurposing for COVID-19 JOURNAL=Frontiers in Immunology VOLUME=11 YEAR=2021 URL=https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2020.603615 DOI=10.3389/fimmu.2020.603615 ISSN=1664-3224 ABSTRACT=
A novel coronavirus, named COVID-19, has become one of the most prevalent and severe infectious diseases in human history. Currently, there are only very few vaccines and therapeutic drugs against COVID-19, and their efficacies are yet to be tested. Drug repurposing aims to explore new applications of approved drugs, which can significantly reduce time and cost compared with