AUTHOR=Zhang Xi , Tang Hao , Fan Jun , Wang Rui , Han Yunwei , Su Song , Gan Yu , Peng Fangyi , Rao Mingyue , Zhang Jianwen , Li Bo , Yang Xiaoli 

TITLE=Case report: A report of the complete pathological response of intrahepatic cholangiocarcinoma after conversion therapy

JOURNAL=Frontiers in Immunology

VOLUME=13

YEAR=2022

URL=https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2022.1051130

DOI=10.3389/fimmu.2022.1051130

ISSN=1664-3224

ABSTRACT=<p>Cholangiocarcinoma (CCA) is a rare disease with poor prognosis, and surgery remains the only curative treatment option. However, surgery is inappropriate for the majority of patients with CCA. Conversion therapy may provide opportunities for the surgical treatment of these patients. Herein, we describe a patient with intrahepatic CCA who was first treated with albumin-bound paclitaxel, cisplatin, and gemcitabine in combination with camrelizumab. The patient then successfully underwent surgery and achieved pathological complete remission. This report can serve as a reference for clinicians regarding conversion therapy for intrahepatic CCA.</p>