AUTHOR=Mahara Gehendra , Tian Cuihong , Xu Xiaojia , Zhu Jinxiu 

TITLE=Breakthrough of glycobiology in the 21st century

JOURNAL=Frontiers in Immunology

VOLUME=Volume 13 - 2022

YEAR=2023

URL=https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2022.1071360

DOI=10.3389/fimmu.2022.1071360

ISSN=1664-3224

ABSTRACT=As modern medicine began to emerge at the turn of the 20th century, glycan-based therapies advanced. DNA- and protein-centered therapies became widely available. The research and development of structurally defined carbohydrates have led to new tools and methods that have sparked interest in the therapeutic applications of glycans. This review focuses on recent developments that have pushed glycan-based therapies into the spotlight in medicine as well as in the technologies powering these initiatives, which we can take as the biggest success of the 21st century.