AUTHOR=Zhou Xiaoliang , Li Kailin , Chen Si , Zhou Wenbin , Li Jing , Huang Qing , Xu Tingting , Gao Zhiyuan , Wang Dongyu , Zhao Shuo , Dong Hao TITLE=Clinical application of transcranial magnetic stimulation in multiple sclerosis JOURNAL=Frontiers in Immunology VOLUME=Volume 13 - 2022 YEAR=2022 URL=https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2022.902658 DOI=10.3389/fimmu.2022.902658 ISSN=1664-3224 ABSTRACT=Multiple sclerosis (MS) is a common chronic, autoimmune-mediated inflammatory and neurodegenerative disease of the central nervous system, the treatment of MS has enormous progress with the Disease-modifying drugs, but the complexity of disease course and clinical symptoms of MS requires the personalized treatment and disease management, including non-pharmacological treatment. Transcranial magnetic stimulation (TMS) is a painless and non-invasive brain stimulation (NIBS) technique, which has been widely used in neurological diseases. In this review, we mainly focus on the progress of physiological assessment and treatment of TMS in MS.