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REVIEW article
Front. Immunol.
Sec. Nutritional Immunology
Volume 15 - 2024 |
doi: 10.3389/fimmu.2024.1413179
This article is part of the Research Topic Intervention Effects of Food-derived Polyphenols and Bioactive Peptides on Chronic Inflammation View all 13 articles
Advances in the application and mechanism of bioactive peptides in the treatment of inflammation
Provisionally accepted- Huzhou University, Huzhou, Zhejiang, China
Inflammation is a normal immune response in organisms, but it often triggers chronic diseases such as colitis and arthritis. Currently, the most widely used anti-inflammatory drugs are non-steroidal anti-inflammatory drugs, albeit they are accompanied by various adverse effects such as hypertension and renal dysfunction. Bioactive peptides (BAPs) provide therapeutic benefits for inflammation and mitigate side effects. Herein, this review focuses on the therapeutic effects of various BAPs on inflammation in different body parts. Emphasis is placed on the immunomodulatory mechanisms of BAPs in treating inflammation, such as regulating the release of inflammatory mediators, modulating MAPK and NF-κB signaling pathways, and reducing oxidative stress reactions for immunomodulation. This review aims to provide a reference for the function, application, and anti-inflammation mechanisms of BAPs.
Keywords: Bioactive peptides, Inflammation, Immunomodulation, inflammatory mediators, pathways
Received: 06 Apr 2024; Accepted: 06 Aug 2024.
Copyright: © 2024 Liu, Zhang, Yu and Shao. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Jingmou Yu, Huzhou University, Huzhou, 313000, Zhejiang, China
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