AUTHOR=Li Shuang-xi , Hu Rui-kang , Kong De-liang , Xu Jing , Bian Qi , Guo Zhi-Yong , Mei Xiao-bin 

TITLE=Efficacy of Telitacicept in treating IgA vasculitis nephritis: a two-case report

JOURNAL=Frontiers in Immunology

VOLUME=Volume 16 - 2025

YEAR=2025

URL=https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2025.1564242

DOI=10.3389/fimmu.2025.1564242

ISSN=1664-3224

ABSTRACT=Telitacicept, a B lymphocyte stimulator/A proliferation-inducing ligand dual-target fusion protein, mainly used for IgA nephropathy and systemic lupus erythematosus. We present two cases where adult patients with IgA vasculitis (IgAV) nephritis were successfully treated with Telitacicept, experienced no adverse reactions during the follow-up. Therefore, Telitacicept represents a promising additional treatment option for patients suffering from IgA vasculitis (IgAV).