AUTHOR=Li Shiyang , Meng Ting , Lin Yuqiu , Xie Dong , Li Zhihua , Jiang Qing 

TITLE=Cutaneous mucormycosis in systemic lupus erythematosus: a case report

JOURNAL=Frontiers in Immunology

VOLUME=Volume 16 - 2025

YEAR=2025

URL=https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2025.1602639

DOI=10.3389/fimmu.2025.1602639

ISSN=1664-3224

ABSTRACT=Mucormycosis is a life-threatening angioinvasive fungal infection caused by the Mucorales acidophilic fungi. In the article we report a case of cutaneous mucosporidiosis caused by infection with Rhizopus arrhizus in a patient with systemic lupus erythematosus (SLE). We analyze the causes of infection and death and concluded that cutaneous mucormycosis is a severe and refractory infection that has higher mortality in immunocompromised individuals or those with immune dysfunction. Early diagnosis and proactive treatment are paramount for a favorable prognosis.