CORRECTION article

Front. Immunol., 02 September 2026

Sec. Autoimmune Disorders

Volume 17 - 2026 | https://doi.org/10.3389/fimmu.2026.1966969

Correction: GAD65 antibody epitopes and genetic background in latent autoimmune diabetes in youth (LADY)

  • 1. National Clinical Research Center for Metabolic Diseases, Key Laboratory of Diabetes Immunology (Central South University), Ministry of Education, and Department of Metabolism and Endocrinology, The Second Xiangya Hospital of Central South University, Changsha, China

  • 2. Department of Endocrinology, Heji Hospital Affiliated to Changzhi Medical College, Changzhi, China

  • 3. Department of Endocrinology, Gansu Provincial Hospital, Lanzhou, China

  • 4. Department of Endocrinology, Xijing Hospital, Fourth Military Medical University, Xi’an, China

  • 5. Department of Endocrinology and Metabolism, Peking University People’s Hospital, Beijing, China

In the published article, there was an error in Table 1 as published. “GADA reactivities to epitopes of GAD65” in Table 1 was improperly named. “N-region” should be corrected to “N-terminal”, and “M-terminal” to “Middle region”. The corrected Table 1 and its caption appear below.

Table 1

GADA reactivities to epitopes of GAD65Young T1DM (n=165)LADY (n=94)Old T1DM (n=149)LADA (n=78)p value
C-terminal57.6% (95)48.9% (46)58.4% (87)33.3% (26) †††§***0.001
N-terminal7.3% (12)12.8% (12)12.8% (19)20.5% (16) ††0.031
Middle region60.0% (99)66.0% (62)54.4% (81)42.3% (33) †§§0.012
Positive for 1 epitope30.9% (51)27.7% (26)32.9% (49)32.1% (25)0.855
Positive for at least 2 epitopes44.2% (73)45.7% (43)43.6% (65)26.9% (21) †§*0.040

Prevalence of epitope-specific GAD65Ab in young T1DM, old T1DM, LADY and LADA patients.

Data are expressed as % (n).

GADA, glutamic acid decarboxylase antibody.

When compared with young T1DM patients, p < 0.05, ††p < 0.01, †††p < 0.001.

When compared with LADY patients, §p < 0.05, §§p < 0.01, §§§p < 0.001.

When compared with old T1DM patients, *p < 0.05, **p < 0.01, ***p < 0.001.

In the published article, there was an error in Figure 1 as published. “Young T1D” should be changed to “young T1DM”, “wereremoved” should be changed to “were removed” and “old T1dM” should changed to “old T1DM”. The corrected Figure 1 and its caption appear below.

Figure 1

In the published article, there was an error. A correction has been made to Materials and Methods, HLA -DR-DQ Genetic Analysis. This sentence previously stated:

“The susceptible HLA haplotypes were DR3 (DRB1*0301-DQA1*0501-DQB1*0201), DR4 (DRB1*0405-DQA1*0303-DQB1*0401), DRB1*0405-DQA1*0301-DQB1*0302, and DR9 (DRB1*0901-DQA1*0303-DQB1*0302) (15, 21–23).”

The corrected sentence appears below:

“The susceptible HLA haplotypes were DR3 (DRB1*0301-DQA1*0501-DQB1*0201), DR4 (DRB1*0405-DQA1*0303-DQB1*0401), DRB1*0405-DQA1*0301-DQB1*0302, and DR9 (DRB1*0901-DQA1*0302-DQB1*0303) (15, 21-23).”

The original article has been updated.

Statements

Publisher’s note

All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.

Summary

Keywords

glutamic acid decarboxylase autoantibody, GAD epitopes, HLA, type 1 diabetes (T1D), latent autoimmune diabetes in adults (LADA), latent autoimmune diabetes in youth

Citation

Peng Y, Li X, Xiang Y, Yan X, Zhou H, Tang X, Cheng J, Niu X, Liu J, Ji Q, Ji L, Huang G and Zhou Z (2026) Correction: GAD65 antibody epitopes and genetic background in latent autoimmune diabetes in youth (LADY). Front. Immunol. 17:1966969. doi: 10.3389/fimmu.2026.1966969

Received

13 August 2026

Accepted

18 August 2026

Published

02 September 2026

Volume

17 - 2026

Edited and reviewed by

Hubert M. Tse, University of Alabama at Birmingham, United States

Updates

Copyright

*Correspondence: Gan Huang,

Disclaimer

All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

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