Frontiers in Immunology

Original Research

Accepted on 23 May 2025

Differential DNA methylation patterns in whole blood from ACPA-positive patients with DMARD naïve rheumatoid arthritis at clinical disease onset.

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Anders Jørgen Svendsen
Jonas Mengel-From
Peter Junker
Christine Dalgård
George Davey Smith
Caroline L Relton
Hannah R Elliott
Kirsten Ohm Kyvik
Hanne Merete Lindegaard
Anne Friesgaard Christensen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1488161

280 views

Original Research

Published on 23 May 2025

C1q reprograms innate immune memory

in Immunological Memory

Inge Jonkman
Maaike M. E. Jacobs
Yutaka Negishi
Julia I. P. van Heck
Vasiliki Matzaraki
Joost H. A. Martens
Marijke Baltissen
Michiel Vermeulen
Zahi A. Fayad
Abraham J. P. Teunissen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1515127

2,099 views

Review

Published on 23 May 2025

Biological mechanisms of pulmonary inflammation and its association with seropositive rheumatoid arthritis

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Peiyue Yang
Yuqing Song
Mingwei Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1530753

1,458 views

Study Protocol

Published on 23 May 2025

Development of an intranasal, universal influenza vaccine in an EU-funded public-private partnership: the FLUniversal consortium

in Vaccines and Molecular Therapeutics

Victor M. Cnossen
Paula C. Leao Moreira
Othmar G. Engelhardt
Jerzy Samolej
Geert H. Groeneveld
Simon P. Jochems
Wesley Huisman
Gabriel K. Pedersen
Katharina Wørzner
Lukas Recek

Frontiers in Immunology

doi 10.3389/fimmu.2025.1568778

2,428 views

Review

Published on 23 May 2025

The role of fibroblast-neutrophil crosstalk in the pathogenesis of inflammatory diseases: a multi-tissue perspective

in Inflammation

Chen Cai
Lanxi Guan
Chenhao Wang
Runjie Hu
Lingling Ou
Qianzhou Jiang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1588667

2,633 views

Review

Published on 23 May 2025

Targeting interleukin-1 signaling for renoprotection

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Daria Bogdanova
Mikhail Y. Samsonov
Svetlana Lebedeva
Darya Bukhanova
Maria Materenchuk
Kerim Mutig

Frontiers in Immunology

doi 10.3389/fimmu.2025.1591197

1,565 views

Case Report

Published on 23 May 2025

Malakoplakia among kidney transplant recipients: case series and literature review

in Alloimmunity and Transplantation

Ali B. Abbasi
Gerardo Gamino
Alan Zambeli-Ljepović
Adrian M. Whelan
Garrett R. Roll
Peter J. Altshuler

Frontiers in Immunology

doi 10.3389/fimmu.2025.1605146

1,205 views

Original Research

Published on 23 May 2025

TSLP pretreatment inhibits M1 macrophage polarization and attenuates LPS-induced iNKT cell-dependent acute lung injury

in Cytokines and Soluble Mediators in Immunity

Ting Zhou
Ziyao Zhang
Yawen Zhan
Meiying Wang
Mi Wu
Xiufang Weng
Younian Xu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1583235

2,214 views

Original Research

Published on 23 May 2025

Lenvatinib versus bevacizumab when combined with PD-1/L1 inhibitor and hepatic arterial infusion chemotherapy in unresectable hepatocellular carcinoma

in Cancer Immunity and Immunotherapy

Lichang Huang
Yujie Xu
Na Liu
Hailong Chen
Zichao Wu
Qijiong Li
Minqiang Lu
Wei Wei
Yaojun Zhang
Minshan Chen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1573098

1,529 views

Original Research

Published on 23 May 2025

Changes in immune cell signatures during early infection reflect decoupling of capillary perfusion and glycocalyx dimensions

in Inflammation

Anna Hunkemöller
Timo Wirth
Alexandros Rovas
Hermann Pavenstädt
Luisa Klotz
Philipp Kümpers

Frontiers in Immunology

doi 10.3389/fimmu.2025.1589959

1,352 views

Clinical Trial

Published on 23 May 2025

First-in-human evaluation of a no-alpha interleukin–2 mutein: safety and preliminary pharmacodynamic and clinical effect

in Cancer Immunity and Immunotherapy

Iraida Caballero Aguirrechu
Braulio Mestre Fernández
Jorge Luis Soriano García
Nora Lim Alonso
Andrés Soto García
Vilma Fleites Calvo
Daines Mariño de la Puente
Geidy Vega Carvajal
Jenny Carolina Ávila Pérez
Ivis Mendoza Hernández

Frontiers in Immunology

doi 10.3389/fimmu.2025.1589042

1,437 views

Review

Published on 23 May 2025

Macrophage regulated cell death: implications and mechanisms in organ transplantation

in Alloimmunity and Transplantation

Jincheng Hou
Chenghao Li
Geng Li
Wai Yen Yim
Bingchuan Geng
Yuqi Cheng
Zihao Wang
Zhengfeng Fan
Fuqiang Tong
Jiawei Shi

Frontiers in Immunology

doi 10.3389/fimmu.2025.1604429

1,555 views

Systematic Review

Published on 23 May 2025

Prognostic value of systemic inflammation response index in patients with glioma: a meta-analysis

in Cancer Immunity and Immunotherapy

Yizhen Jiang
Lin Zhou

Frontiers in Immunology

doi 10.3389/fimmu.2025.1576845

1,124 views

Original Research

Published on 23 May 2025

NMB promotes the progression of colorectal cancer by regulating the NF-κB/P65 signaling pathway

in Cancer Immunity and Immunotherapy

Jiaxin Fan
Yuming Liu
Jiajia Wang
Tian Yao
Shaoxiong Bai
Xiaole Ma
Hao Chen
Yuhao Chen
Huiyang Gao
Yuntong Guo

Frontiers in Immunology

doi 10.3389/fimmu.2025.1596451

1,302 views

Review

Published on 23 May 2025

Treg cell therapy manufacturability: current state of the art, challenges and new opportunities

in T Cell Biology

Janelle Stoops
Tara Morton
James Powell
Amanda L. Pace
Jeffrey A. Bluestone

Frontiers in Immunology

doi 10.3389/fimmu.2025.1604483

3,196 views
1 citation

Original Research

Published on 23 May 2025

Innate immune cell barrier-related genes inform precision prognosis in pancreatic cancer

in Cancer Immunity and Immunotherapy

Qiang Luo
Tingting Jiang
Dacheng Xie
Xiaojia Li
Keping Xie

Frontiers in Immunology

doi 10.3389/fimmu.2025.1559373

1,585 views