Frontiers in Immunology | Multiple Sclerosis and Neuroimmunology

Review

Published on 16 May 2025

From sensation to regulation: the diverse functions of peripheral sensory nervous system

in Multiple Sclerosis and Neuroimmunology

Yixiao Mei
Bing-Lin Zhou
Da Zhong
Xuan-Jie Zheng
Yu-Tao Deng
Lina Yu
Bao-Chun Jiang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1575917

9,700 views
4 citations

Review

Published on 15 May 2025

The role of microglia in multiple sclerosis: implications for treatment with Bruton’s tyrosine kinase inhibitors

in Multiple Sclerosis and Neuroimmunology

Patrick Vermersch
Laura Airas
Thomas Berger
Florian Deisenhammer
Nikolaos Grigoriadis
Hans-Peter Hartung
Melinda Magyari
Veronica Popescu
Carlo Pozzilli
Maura Pugliatti

Frontiers in Immunology

doi 10.3389/fimmu.2025.1495529

7,879 views
8 citations

Opinion

Published on 08 May 2025

Proteomics reveals molecular subtypes in traumatic brain injury patients: new perspectives for precision treatment strategies

in Multiple Sclerosis and Neuroimmunology

Suqin Zhang
Qi Xu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1606268

2,102 views
1 citation

Review

Published on 08 May 2025

Astrocyte-mediated inflammatory responses in traumatic brain injury: mechanisms and potential interventions

in Multiple Sclerosis and Neuroimmunology

Haifeng Zhang
Xian Zhang
Yan Chai
Yuhua Wang
Jianning Zhang
Xin Chen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1584577

9,935 views
26 citations

Original Research

Published on 05 May 2025

Development and validation of predictive models for meige syndrome patients based on oxidative stress markers

in Multiple Sclerosis and Neuroimmunology

Yingjie Zhu
Runing Fu
Ziang Wang
Xinjie Zhu
Pengbo Feng
Xinyu Feng
Wenping Lian

Frontiers in Immunology

doi 10.3389/fimmu.2025.1536109

2,420 views

Original Research

Published on 28 Apr 2025

Comparative study of subacute combined degeneration of the spinal cord due to nitrous oxide abuse and vitamin B12 deficiency

in Multiple Sclerosis and Neuroimmunology

Sedine Marie Desiree Nina Agbo
Xiaohui Duan
Li Wang
Mingrui Dong
Qian Wang
Xiaojing Cai
Fang Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1567541

3,891 views
1 citation

Review

Published on 25 Apr 2025

Controversies and insights into cytokine regulation of neurogenesis and behavior in adult rodents

in Multiple Sclerosis and Neuroimmunology

Rodrigo Daniel Sepúlveda-Cuéllar
Diego Alberto Soria-Medina
Irma Cañedo-Solares
Fernando Gómez-Chávez
Liliana Monserrat Molina-López
María Yolanda Cruz-Martínez
Dolores Correa

Frontiers in Immunology

doi 10.3389/fimmu.2025.1550660

3,944 views
1 citation

Original Research

Published on 22 Apr 2025

Serum angiotensin type-1 receptor autoantibodies and neurofilament light chain as markers of neuroaxonal damage in post-COVID patients

in Multiple Sclerosis and Neuroimmunology

Ana I. Rodriguez-Perez
Gemma Serrano-Heras
Carmen M. Labandeira
Laura Camacho-Meño
Beatriz Castro-Robles
Juan A. Suarez-Quintanilla
Mónica Muñoz-López
Pepa Piqueras-Landete
María J. Guerra
Tomas Segura

Frontiers in Immunology

doi 10.3389/fimmu.2025.1571027

4,717 views
2 citations

Original Research

Published on 17 Apr 2025

Shared circulating diagnostic biomarkers and molecular mechanisms in ischemic stroke and systemic lupus erythematosus

in Multiple Sclerosis and Neuroimmunology

Xiaoyi Ma
Lifei Huang
Huanhuan Yan

Frontiers in Immunology

doi 10.3389/fimmu.2025.1565379

6,109 views

Original Research

Published on 16 Apr 2025

The P2X7R-antagonist AFC-5128 ameliorates chronic experimental autoimmune encephalomyelitis in a preventive and therapeutic paradigm

in Multiple Sclerosis and Neuroimmunology

Robert Hoffrogge
Anna Karachunskaya
Neele Heitmann
Steffen Haupeltshofer
Xiomara Pedreiturria
Katharina Klöster
Verian Bader
Konstanze F. Winklhofer
Michael Hamacher
Bert Klebl

Frontiers in Immunology

doi 10.3389/fimmu.2025.1554999

4,973 views

Original Research

Published on 15 Apr 2025

Comparison of commercial and in-house tissue-based and cell-based assays for the detection of autoantibodies targeting neuronal surface proteins: a prospective cohort study

in Multiple Sclerosis and Neuroimmunology

David Goncalves
Marie Benaiteau
Véronique Rogemond
Sterenn Closs
Anne-Laurie Pinto
Maroua Dhairi
Marine Villard
Géraldine Picard
Nicole Fabien
Jérôme Honnorat

Frontiers in Immunology

doi 10.3389/fimmu.2025.1563877

3,370 views
1 citation

Original Research

Published on 11 Apr 2025

Worse recovery from acute attacks and faster disability accumulation highlights the unmet need for improved treatment in patients with late-onset neuromyelitis optica spectrum disorders (COPTER-LO study)

in Multiple Sclerosis and Neuroimmunology

Julian Reza Kretschmer
Daria Tkachenko
Tania Kümpfel
Joachim Havla
Daniel Engels
Friedemann Paul
Patrick Schindler
Judith Bellmann-Strobl
Achim Berthele
Katrin Giglhuber

Frontiers in Immunology

doi 10.3389/fimmu.2025.1575613

6,143 views
4 citations

Case Report

Published on 04 Apr 2025

Switching to ublituximab from prior anti-CD20 monoclonal antibody therapy: a case report series

in Multiple Sclerosis and Neuroimmunology

Regina Berkovich
Jonathan Calkwood
Heidi Crayton
April Erwin
Simon Faissner
Ralf Gold
Joshua Katz
Mark Leekoff

Frontiers in Immunology

doi 10.3389/fimmu.2025.1527102

7,874 views
1 citation

Mini Review

Published on 02 Apr 2025

The role of NLRP3 inflammasome in multiple sclerosis: pathogenesis and pharmacological application

in Multiple Sclerosis and Neuroimmunology

Wen-Gang Zhang
Xiao-Rui Zheng
Yi Yao
Wei-Jia Sun
Bo-Zong Shao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1572140

4,299 views
4 citations

Review

Published on 01 Apr 2025

Roles of METTL3 and NLRP3 in pyroptosis and prospects in SCIRI

in Multiple Sclerosis and Neuroimmunology

Xiaoqing Guan
Fengyi Zhang
Ning Zhang
Guangchun Li
Fei Yin

Frontiers in Immunology

doi 10.3389/fimmu.2025.1552704

4,075 views
4 citations

Mini Review

Published on 25 Mar 2025

Advocating the role of trained immunity in the pathogenesis of ME/CFS: a mini review

in Multiple Sclerosis and Neuroimmunology

Bart Humer
Willem A. Dik
Marjan A. Versnel

Frontiers in Immunology

doi 10.3389/fimmu.2025.1483764

6,576 views
5 citations

Original Research

Published on 24 Mar 2025

Integrated bioinformatics analysis and biological experiments to identify key immune genes in vascular dementia

in Multiple Sclerosis and Neuroimmunology

Yilong Zhao
Wen Xing
Weiqi Chen
Yilong Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1560438

4,916 views
2 citations

Review

Published on 21 Mar 2025

Current challenges in secondary progressive multiple sclerosis: diagnosis, activity detection and treatment

in Multiple Sclerosis and Neuroimmunology

Luis Brieva
Carmen Calles
Lamberto Landete
Celia Oreja-Guevara

Frontiers in Immunology

doi 10.3389/fimmu.2025.1543649

10,493 views
6 citations

Original Research

Published on 14 Mar 2025

Comparison of the clinical and laboratory characteristics of neuromyelitis optica spectrum disorder with or without cerebrospinal fluid oligoclonal bands: a cohort with 36-month follow-up

in Multiple Sclerosis and Neuroimmunology

Wenbo Yang
Xiaoni Liu
Jie Wei
Hai Yu
Wanqing Wu
Jingguo Wang
Bo Deng
Xiaoqin Wu
Xiangjun Chen
Xiang Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1536853

2,960 views

Case Report

Published on 14 Mar 2025

Case Report: CASPR2-associated autoimmune encephalitis with NF155 Antibody-positive autoimmune nodopathies: a rare case with hyponatremia onset

in Multiple Sclerosis and Neuroimmunology

Wen-Ya Wang
Jing-Ying Huang
Ying Xue
An-Ran Zhang
Ruo-Yi Guo
Zhen Jia
Ya-Fei Sun
Bin Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1519878

2,595 views

Case Report

Published on 11 Mar 2025

Case Report: Ofatumumab treatment for concomitant multiple sclerosis and idiopathic thrombocytopenic purpura

in Multiple Sclerosis and Neuroimmunology

Yuki Yokota
Makoto Hara
Hideto Nakajima

Frontiers in Immunology

doi 10.3389/fimmu.2025.1515776

4,461 views

Original Research

Published on 05 Mar 2025

Positive allosteric modulation of AMPA receptors via PF4778574 leads to reduced demyelination and clinical disability in experimental models of multiple sclerosis

in Multiple Sclerosis and Neuroimmunology

Mustafa Sindi
Michael Dietrich
Diana Klees
Joel Gruchot
Christina Hecker
John Silbereis
Andrea Issberner
Hans-Peter Hartung
Tobias Ruck
Holger Stark

Frontiers in Immunology

doi 10.3389/fimmu.2025.1532877

4,267 views
2 citations

Correction

Published on 05 Mar 2025

Corrigendum: Blood biomarker dynamics in people with relapsing multiple sclerosis treated with cladribine tablets: results of the 2-year MAGNIFY-MS study

in Multiple Sclerosis and Neuroimmunology

Heinz Wiendl
Frederik Barkhof
Xavier Montalban
Anat Achiron
Tobias Derfuss
Andrew Chan
Suzanne Hodgkinson
Alexandre Prat
Letizia Leocani
Klaus Schmierer

Frontiers in Immunology

doi 10.3389/fimmu.2025.1571978

2,071 views
1 citation

Original Research

Published on 03 Mar 2025

The nomogram model predicts relapse risk in myelin oligodendrocyte glycoprotein antibody-associated disease: a single-center study

in Multiple Sclerosis and Neuroimmunology

Jiafei Cheng
Zhuoran Wang
Jing Wang
Xiaomin Pang
Jianli Wang
Meini Zhang
Junhong Guo
Huaxing Meng

Frontiers in Immunology

doi 10.3389/fimmu.2025.1527057

4,339 views
6 citations

1,516 articles

articles

From sensation to regulation: the diverse functions of peripheral sensory nervous system

The role of microglia in multiple sclerosis: implications for treatment with Bruton’s tyrosine kinase inhibitors

Proteomics reveals molecular subtypes in traumatic brain injury patients: new perspectives for precision treatment strategies

Astrocyte-mediated inflammatory responses in traumatic brain injury: mechanisms and potential interventions

Development and validation of predictive models for meige syndrome patients based on oxidative stress markers

Comparative study of subacute combined degeneration of the spinal cord due to nitrous oxide abuse and vitamin B12 deficiency

Controversies and insights into cytokine regulation of neurogenesis and behavior in adult rodents

Serum angiotensin type-1 receptor autoantibodies and neurofilament light chain as markers of neuroaxonal damage in post-COVID patients

Shared circulating diagnostic biomarkers and molecular mechanisms in ischemic stroke and systemic lupus erythematosus

The P2X7R-antagonist AFC-5128 ameliorates chronic experimental autoimmune encephalomyelitis in a preventive and therapeutic paradigm

Comparison of commercial and in-house tissue-based and cell-based assays for the detection of autoantibodies targeting neuronal surface proteins: a prospective cohort study

Worse recovery from acute attacks and faster disability accumulation highlights the unmet need for improved treatment in patients with late-onset neuromyelitis optica spectrum disorders (COPTER-LO study)

Switching to ublituximab from prior anti-CD20 monoclonal antibody therapy: a case report series

The role of NLRP3 inflammasome in multiple sclerosis: pathogenesis and pharmacological application

Roles of METTL3 and NLRP3 in pyroptosis and prospects in SCIRI

Advocating the role of trained immunity in the pathogenesis of ME/CFS: a mini review

Integrated bioinformatics analysis and biological experiments to identify key immune genes in vascular dementia

Current challenges in secondary progressive multiple sclerosis: diagnosis, activity detection and treatment

Comparison of the clinical and laboratory characteristics of neuromyelitis optica spectrum disorder with or without cerebrospinal fluid oligoclonal bands: a cohort with 36-month follow-up

Case Report: CASPR2-associated autoimmune encephalitis with NF155 Antibody-positive autoimmune nodopathies: a rare case with hyponatremia onset

Case Report: Ofatumumab treatment for concomitant multiple sclerosis and idiopathic thrombocytopenic purpura

Positive allosteric modulation of AMPA receptors via PF4778574 leads to reduced demyelination and clinical disability in experimental models of multiple sclerosis

Corrigendum: Blood biomarker dynamics in people with relapsing multiple sclerosis treated with cladribine tablets: results of the 2-year MAGNIFY-MS study

The nomogram model predicts relapse risk in myelin oligodendrocyte glycoprotein antibody-associated disease: a single-center study