Frontiers in Immunology | Primary Immunodeficiencies

Original Research

Published on 05 Dec 2024

Complications of the Bacillus Calmette-Guerin vaccine as an early warning sign of inborn errors of immunity: a report of 197 patients

in Primary Immunodeficiencies

Mohammad Reza Fazlollahi
Ali Goudarzi
Maryam Nourizadeh
Zahra Alizadeh
Shaghayegh Tajik
Mohsen Badalzadeh
Shokouh Azam Sarafzadeh
Maryam Mahlooji Rad
Zeinab Adab
Leila Moradi

Frontiers in Immunology

doi 10.3389/fimmu.2024.1477499

1,871 views
1 citation

Case Report

Published on 29 Nov 2024

Case report: A cyclic neutropenia patient with ELANE mutation accompanied by hemophagocytic lymphohistiocytosis

in Primary Immunodeficiencies

Lang Yu
Yulin Li
Wenhui Li
Yishi Zhang
Wenli He
Xuemei Tang
Yunfei An
Xiaodong Zhao

Frontiers in Immunology

doi 10.3389/fimmu.2024.1474429

1,277 views

Case Report

Published on 20 Nov 2024

Perspectives in newborn screening for SCID in Japan. Case report: newborn screening identified X-linked severe combined immunodeficiency with a novel IL2RG variant

in Primary Immunodeficiencies

Shiro Beppu
Takuro Nishikawa
Dan Tomomasa
Atsushi Hijikata
Hiroshi Kasabata
Hideyuki Terazono
Kazuro Ikawa
Tatsuro Nakamura
Shogo Horikawa
Jun Nagahama

Frontiers in Immunology

doi 10.3389/fimmu.2024.1478411

1,756 views

Case Report

Published on 18 Nov 2024

Case report: Pediatric patient with severe clinical course of CTLA-4 insufficiency treated with HSCT

in Primary Immunodeficiencies

Katarzyna Drabko
Julia Zarychta
Adrian Kowalczyk
Magdalena Cienkusz

Frontiers in Immunology

doi 10.3389/fimmu.2024.1484467

1,446 views
1 citation

Original Research

Published on 15 Nov 2024

Technical challenges of intracellular flow cytometry-based assays as a functional complement to diagnosis of signaling defects of inborn errors of immunity: PI3K pathway as a case of study

in Primary Immunodeficiencies

Lucía del Pino Molina
Keren Reche Yebra
Yolanda Soto Serrano
Álvaro Clemente Bernal
Carmen L. Avendaño-Monje
J. Gonzalo Ocejo-Vinyals
Rebeca Rodríguez Pena
Eduardo López Granados

Frontiers in Immunology

doi 10.3389/fimmu.2024.1476218

1,683 views
1 citation

Case Report

Published on 13 Nov 2024

Case report: A novel JAK3 homozygous variant in a patient with severe combined immunodeficiency and persistent COVID-19

in Primary Immunodeficiencies

Renan Cesar Sbruzzi
Mayara Jorgens Prado
Bibiana Fam
Helena Ashton Prolla
Alessandra Hellwig
Grazielle Motta Rodrigues
Fernanda de-Paris
Mariana Jobim
Osvaldo Artigalás
Yoann Seeleuthner

Frontiers in Immunology

doi 10.3389/fimmu.2024.1472957

1,525 views

Original Research

Published on 11 Nov 2024

CXCR4 antagonism ameliorates leukocyte abnormalities in a preclinical model of WHIM syndrome

in Primary Immunodeficiencies

Lilian Roland
Chi Huu Nguyen
Katarina Zmajkovicova
Mélanie Khamyath
Maria Kalogeraki
Bérénice Schell
Vanessa Gourhand
Vincent Rondeau
Zeina Abou Nader
Halenya Monticelli

Frontiers in Immunology

doi 10.3389/fimmu.2024.1468823

1,628 views

Original Research

Published on 07 Nov 2024

Heterogeneous phenotype of a Chinese Familial WHIM syndrome with CXCR4V340fs gain-of-function mutation

in Primary Immunodeficiencies

Yu Huang
Lu Li
Ran Chen
Lang Yu
Shunkai Zhao
Yanjun Jia
Ying Dou
Zhiyong Zhang
Yunfei An
Xuemei Tang

Frontiers in Immunology

doi 10.3389/fimmu.2024.1460990

1,226 views

Original Research

Published on 30 Oct 2024

Characterizing CD38 expression in terminally differentiated B cells using variable lymphocyte receptor B tetramers

in Primary Immunodeficiencies

Arundhati G. Nair
Matilde Leon-Ponte
Vy HD Kim
Gordon Sussman
Götz R.A. Ehrhardt
Eyal Grunebaum

Frontiers in Immunology

doi 10.3389/fimmu.2024.1451232

1,240 views

Case Report

Published on 30 Oct 2024

Progressive pseudorheumatoid dysplasia involving a novel CCN6 mutation: a case report

in Primary Immunodeficiencies

Yu Li
Zhengping Huang
Yun Yan
Feng Guo
Gang Wei
Yue Wang
Yu Xie

Frontiers in Immunology

doi 10.3389/fimmu.2024.1445420

1,251 views

Original Research

Published on 23 Oct 2024

Calculated globulin can be used as a screening test for antibody deficiency in children and adolescents

in Primary Immunodeficiencies

Cristina Frias Sartorelli de Toledo Piza
Carolina Sanchez Aranda
Dirceu Solé
Stephen Jolles
Antonio Condino-Neto

Frontiers in Immunology

doi 10.3389/fimmu.2024.1495564

1,526 views

Original Research

Published on 16 Oct 2024

The impact of immune dysregulation on the risk of malignancy in common variable immunodeficiency: insights from a multicenter study

in Primary Immunodeficiencies

Marta Dafne Cabañero-Navalon
Victor Garcia-Bustos
Héctor Balastegui-Martin
Carmen Bracke
Lourdes Mateu
Xavier Solanich
Juan Luis Carrillo-Linares
Angel Robles-Marhuenda
Francesc Puchades
Ana Pelaez Ballesta

Frontiers in Immunology

doi 10.3389/fimmu.2024.1465159

1,976 views

Review

Published on 14 Oct 2024

Functional role of UNC13D in immune diseases and its therapeutic applications

in Primary Immunodeficiencies

Van-Thanh Duong
Dongjun Lee
Yun Hak Kim
Sae-Ock Oh

Frontiers in Immunology

doi 10.3389/fimmu.2024.1460882

3,462 views
3 citations

Original Research

Published on 10 Oct 2024

Sentiment analysis of subcutaneous and intravenous immunoglobulin therapy: public healthcare perception through social media discourse

in Primary Immunodeficiencies

Alejandro Tarango-García
Silvia Rodríguez-Narciso
Netzahualcóyotl Castañeda-Leyva
Hannia M. Prieto-Nevárez
Saul O. Lugo Reyes
Francisco J. Espinosa-Rosales
Sara Elva Espinosa-Padilla
Aidé T. Staines-Boone
Luis F. Torres-Bernal
Aristóteles Álvarez-Cardona

Frontiers in Immunology

doi 10.3389/fimmu.2024.1467852

1,147 views

Perspective

Published on 02 Oct 2024

Newborn screening for severe combined immunodeficiency in Malaysia: current status, challenges and progress

in Primary Immunodeficiencies

Wai Leng Chang
Lokman Mohd Noh
Amir Hamzah Abdul Latiff
Kent Chee Keen Woo
Intan Hakimah Ismail
Intan Juliana Abd Hamid
Sangeetha Siniah
Mohd Azri Zainal Abidin
Marina Sham
Adiratna Mat Ripen

Frontiers in Immunology

doi 10.3389/fimmu.2024.1456769

1,541 views

Original Research

Published on 02 Oct 2024

Newborn screening for SCID: the very first prospective pilot study from Türkiye

in Primary Immunodeficiencies

Sule Haskologlu
Senem Kocak
Lale Satiroglu Tufan
Fethiye Eken Aksoy
Dilan Bastug
Deniz Aslar Oner
Candan Islamoglu
Kubra Baskin
Saliha Esenboga
Deniz Acican

Frontiers in Immunology

doi 10.3389/fimmu.2024.1384195

2,386 views