Frontiers in Immunology | Systems Immunology

Original Research

Published on 28 Apr 2023

Response to primary chemoradiotherapy of locally advanced oropharyngeal carcinoma is determined by the degree of cytotoxic T cell infiltration within tumor cell aggregates

in Systems Immunology

Maximilian Haist
Justus Kaufmann
Ivan-Maximiliano Kur
Stefanie Zimmer
Stephan Grabbe
Heinz Schmidberger
Andreas Weigert
Arnulf Mayer

Frontiers in Immunology

doi 10.3389/fimmu.2023.1070203

4,465 views
9 citations

Original Research

Published on 27 Apr 2023

Prediction of liver cancer prognosis based on immune cell marker genes

in Systems Immunology

Jianfei Liu
Junjie Qu
Lingling Xu
Chen Qiao
Guiwen Shao
Xin Liu
Hui He
Jian Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2023.1147797

6,148 views
11 citations

Original Research

Published on 26 Apr 2023

Immunological role and prognostic value of the SKA family in pan-cancer analysis

in Systems Immunology

Zhengtian Li
Lanying Huang
Jiachen Li
Wenkang Yang
Weichao Li
Qiuzhong Long
Xinyu Dai
Hongtao Wang
Gang Du

Frontiers in Immunology

doi 10.3389/fimmu.2023.1012999

5,228 views
5 citations

Original Research

Published on 25 Apr 2023

Prediction of HLA genotypes from single-cell transcriptome data

in Systems Immunology

Benjamin D. Solomon
Hong Zheng
Laura W. Dillon
Jason D. Goldman
Christopher S. Hourigan
James R. Heath
Purvesh Khatri

Frontiers in Immunology

doi 10.3389/fimmu.2023.1146826

10,494 views
11 citations

Original Research

Published on 24 Apr 2023

Combination of machine learning-based bulk and single-cell genomics reveals necroptosis-related molecular subtypes and immunological features in autism spectrum disorder

in Systems Immunology

Lichun Liu
Qingxian Fu
Huaili Ding
Hua Jiang
Zhidong Zhan
Yongxing Lai

Frontiers in Immunology

doi 10.3389/fimmu.2023.1139420

6,491 views
10 citations

Original Research

Published on 18 Apr 2023

Performance comparison of TCR-pMHC prediction tools reveals a strong data dependency

in Systems Immunology

Lihua Deng
Cedric Ly
Sina Abdollahi
Yu Zhao
Immo Prinz
Stefan Bonn

Frontiers in Immunology

doi 10.3389/fimmu.2023.1128326

9,761 views
49 citations

Original Research

Published on 14 Apr 2023

Multi-omics analysis reveals a macrophage-related marker gene signature for prognostic prediction, immune landscape, genomic heterogeneity, and drug choices in prostate cancer

in Systems Immunology

Weian Zhu
Jianjie Wu
Jiongduan Huang
Dongming Xiao
Fengao Li
Chenglun Wu
Xiaojuan Li
Hengda Zeng
Jiayu Zheng
Wenjie Lai

Frontiers in Immunology

doi 10.3389/fimmu.2023.1122670

8,035 views
13 citations

Original Research

Published on 06 Apr 2023

Severe COVID-19 and non-COVID-19 severe sepsis converge transcriptionally after a week in the intensive care unit, indicating common disease mechanisms

in Systems Immunology

Andy Y. An
Arjun Baghela
Peter Zhang
Reza Falsafi
Amy H. Lee
Uriel Trahtemberg
Andrew J. Baker
Claudia C. dos Santos
Robert E. W. Hancock

Frontiers in Immunology

doi 10.3389/fimmu.2023.1167917

5,502 views
16 citations

Original Research

Published on 03 Apr 2023

Compartmentalized spatial profiling of the tumor microenvironment in head and neck squamous cell carcinoma identifies immune checkpoint molecules and tumor necrosis factor receptor superfamily members as biomarkers of response to immunotherapy

in Systems Immunology

Habib Sadeghirad
Ning Liu
James Monkman
Ning Ma
Bassem Ben Cheikh
Niyati Jhaveri
Chin Wee Tan
Majid Ebrahimi Warkiani
Mark N. Adams
Quan Nguyen

Frontiers in Immunology

doi 10.3389/fimmu.2023.1135489

12,510 views
32 citations

Original Research

Published on 03 Apr 2023

Machine learning for the prediction of all-cause mortality in patients with sepsis-associated acute kidney injury during hospitalization

in Systems Immunology

Hongshan Zhou
Leping Liu
Qinyu Zhao
Xin Jin
Zhangzhe Peng
Wei Wang
Ling Huang
Yanyun Xie
Hui Xu
Lijian Tao

Frontiers in Immunology

doi 10.3389/fimmu.2023.1140755

10,241 views
41 citations

Original Research

Published on 03 Apr 2023

Distinct subpopulations of DN1 thymocytes exhibit preferential γδ T lineage potential

in Systems Immunology

Seungyoul Oh
Xin Liu
Sara Tomei
Mengxiao Luo
Jarrod P. Skinner
Stuart P. Berzins
Shalin H. Naik
Daniel H. D. Gray
Mark M. W. Chong

Frontiers in Immunology

doi 10.3389/fimmu.2023.1106652

7,183 views
11 citations

Original Research

Published on 30 Mar 2023

Bioinformatics-integrated screening of systemic sclerosis-specific expressed markers to identify therapeutic targets

in Systems Immunology

Jiahui Jin
Yifan Liu
Qinyu Tang
Xin Yan
Miao Jiang
Xu Zhao
Jie Chen
Caixia Jin
Qingjian Ou
Jingjun Zhao

Frontiers in Immunology

doi 10.3389/fimmu.2023.1125183

9,048 views
12 citations

Original Research

Published on 27 Mar 2023

Deciphering the complete human-monkeypox virus interactome: Identifying immune responses and potential drug targets

in Systems Immunology

Raghav Kataria
Simardeep Kaur
Rakesh Kaundal

Frontiers in Immunology

doi 10.3389/fimmu.2023.1116988

15,020 views
16 citations

Methods

Published on 23 Mar 2023

PathwayKO: An integrated platform for deciphering the systems-level signaling pathways

in Systems Immunology

Hannan Ai
Fanmei Meng
Yuncan Ai

Frontiers in Immunology

doi 10.3389/fimmu.2023.1103392

4,987 views

Original Research

Published on 21 Mar 2023

Molecular tracking of insulin resistance and inflammation development on visceral adipose tissue

in Systems Immunology

Antonio Bensussen
José Antonio Torres-Magallanes
Elena Roces de Álvarez-Buylla

Frontiers in Immunology

doi 10.3389/fimmu.2023.1014778

8,218 views
49 citations

Technology and Code

Published on 21 Mar 2023

VIGET: A web portal for study of vaccine-induced host responses based on Reactome pathways and ImmPort data

in Systems Immunology

Timothy Brunson
Nasim Sanati
Anthony Huffman
Anna Maria Masci
Jie Zheng
Michael F. Cooke
Patrick Conley
Yongqun He
Guanming Wu

Frontiers in Immunology

doi 10.3389/fimmu.2023.1141030

4,618 views
5 citations

Original Research

Published on 15 Mar 2023

Establishing a human bone marrow single cell reference atlas to study ageing and diseases

in Systems Immunology

Nicole Yee Shin Lee
Mengwei Li
Kok Siong Ang
Jinmiao Chen

Frontiers in Immunology

doi 10.3389/fimmu.2023.1127879

24,741 views
24 citations

Original Research

Published on 10 Mar 2023

A multiscale mechanistic model of human dendritic cells for in-silico investigation of immune responses and novel therapeutics discovery

in Systems Immunology

Sara Sadat Aghamiri
Bhanwar Lal Puniya
Rada Amin
Tomáš Helikar

Frontiers in Immunology

doi 10.3389/fimmu.2023.1112985

5,986 views
12 citations

Original Research

Published on 02 Mar 2023

A theoretical framework of immune cell phenotypic classification and discovery

in Systems Immunology

Yuzhe Hu
Chen Liu
Wenling Han
Pingzhang Wang

Frontiers in Immunology

doi 10.3389/fimmu.2023.1128423

10,189 views
21 citations

Technology and Code

Published on 02 Mar 2023

YOUPI: Your powerful and intelligent tool for segmenting cells from imaging mass cytometry data

in Systems Immunology

Yvonne Scuiller
Patrice Hemon
Marion Le Rochais
Jacques-Olivier Pers
Christophe Jamin
Nathan Foulquier

Frontiers in Immunology

doi 10.3389/fimmu.2023.1072118

4,626 views
8 citations

Original Research

Published on 01 Mar 2023

In silico analysis of single nucleotide polymorphism (rs34377097) of TBXA2R gene and pollen induced bronchial asthma susceptibility in West Bengal population, India

in Systems Immunology

Indranil Ganai
Ishita Saha
Priyajit Banerjee
Arghya Laha
Saheen Sultana
Nasima Sultana
Himani Biswas
Saibal Moitra
Sanjoy Podder

Frontiers in Immunology

doi 10.3389/fimmu.2023.1089514

3,426 views
6 citations

Correction

Published on 23 Feb 2023

Corrigendum: The Vacc-SeqQC project: Benchmarking RNA-Seq for clinical vaccine studies

in Systems Immunology

Johannes B. Goll
Steven E. Bosinger
Travis L. Jensen
Hasse Walum
Tyler Grimes
Gregory K. Tharp
Muktha S. Natrajan
Azra Blazevic
Richard D. Head
Casey E. Gelber

Frontiers in Immunology

doi 10.3389/fimmu.2023.1163550

1,877 views
1 citation

Original Research

Published on 21 Feb 2023

Integration of bulk RNA sequencing and single-cell analysis reveals a global landscape of DNA damage response in the immune environment of Alzheimer’s disease

in Systems Immunology

Yongxing Lai
Han Lin
Manli Chen
Xin Lin
Lijuan Wu
Yinan Zhao
Fan Lin
Chunjin Lin

Frontiers in Immunology

doi 10.3389/fimmu.2023.1115202

8,566 views
8 citations

Original Research

Published on 17 Feb 2023

Sequencing technology as a major impetus in the advancement of studies into rheumatism: A bibliometric study

in Systems Immunology

Runzhi Huang
Jieling Tang
Siqiao Wang
Yifan Liu
Mengyi Zhang
Minghao Jin
Hengwei Qin
Weijin Qian
Yuwei Lu
Yiting Yang

Frontiers in Immunology

doi 10.3389/fimmu.2023.1067830

4,361 views
6 citations

545 articles

articles

Response to primary chemoradiotherapy of locally advanced oropharyngeal carcinoma is determined by the degree of cytotoxic T cell infiltration within tumor cell aggregates

Prediction of liver cancer prognosis based on immune cell marker genes

Immunological role and prognostic value of the SKA family in pan-cancer analysis

Prediction of HLA genotypes from single-cell transcriptome data

Combination of machine learning-based bulk and single-cell genomics reveals necroptosis-related molecular subtypes and immunological features in autism spectrum disorder

Performance comparison of TCR-pMHC prediction tools reveals a strong data dependency

Multi-omics analysis reveals a macrophage-related marker gene signature for prognostic prediction, immune landscape, genomic heterogeneity, and drug choices in prostate cancer

Severe COVID-19 and non-COVID-19 severe sepsis converge transcriptionally after a week in the intensive care unit, indicating common disease mechanisms

Compartmentalized spatial profiling of the tumor microenvironment in head and neck squamous cell carcinoma identifies immune checkpoint molecules and tumor necrosis factor receptor superfamily members as biomarkers of response to immunotherapy

Machine learning for the prediction of all-cause mortality in patients with sepsis-associated acute kidney injury during hospitalization

Distinct subpopulations of DN1 thymocytes exhibit preferential γδ T lineage potential

Bioinformatics-integrated screening of systemic sclerosis-specific expressed markers to identify therapeutic targets

Deciphering the complete human-monkeypox virus interactome: Identifying immune responses and potential drug targets

PathwayKO: An integrated platform for deciphering the systems-level signaling pathways

Molecular tracking of insulin resistance and inflammation development on visceral adipose tissue

VIGET: A web portal for study of vaccine-induced host responses based on Reactome pathways and ImmPort data

Establishing a human bone marrow single cell reference atlas to study ageing and diseases

A multiscale mechanistic model of human dendritic cells for in-silico investigation of immune responses and novel therapeutics discovery

A theoretical framework of immune cell phenotypic classification and discovery

YOUPI: Your powerful and intelligent tool for segmenting cells from imaging mass cytometry data

In silico analysis of single nucleotide polymorphism (rs34377097) of TBXA2R gene and pollen induced bronchial asthma susceptibility in West Bengal population, India

Corrigendum: The Vacc-SeqQC project: Benchmarking RNA-Seq for clinical vaccine studies

Integration of bulk RNA sequencing and single-cell analysis reveals a global landscape of DNA damage response in the immune environment of Alzheimer’s disease

Sequencing technology as a major impetus in the advancement of studies into rheumatism: A bibliometric study