AUTHOR=Puelles Luis 

TITLE=An illustrated summary of the prosomeric model

JOURNAL=Frontiers in Mammal Science

VOLUME=Volume 3 - 2024

YEAR=2024

URL=https://www.frontiersin.org/journals/mammal-science/articles/10.3389/fmamm.2024.1456996

DOI=10.3389/fmamm.2024.1456996

ISSN=2813-4699

ABSTRACT=This review summarizes and illustrates the assumptions, structure and updates that apply to the prosomeric model of brain development. The anteroposterior structure is summarized in terms of tagmata, proneuromeres and neuromeres. The primary dorsoventral structure relates to the 4 longitudinal zones of W.His (1893): the floor, basal, alar, and roof plates. There exists a secondary microzonation of these primary longitudinal zones, and the alar plate domains of the neuromeres seem to show in some cases an anteroposterior tripartition. Topological consideration of the axial bending of the brain and practical consequences as regards section planes are presented. The midline, a fundamental reference, is described in detail in terms of floor, roof and acroterminal components and landmarks. Finally, the relationship of axonal tracts and blood vessels to the subdivisions in the model are briefly treated.