AUTHOR=Moroni Federico , Naya-Català Fernando , Piazzon M. Carla , Rimoldi Simona , Calduch-Giner Josep , Giardini Alberto , Martínez Inés , Brambilla Fabio , Pérez-Sánchez Jaume , Terova Genciana 

TITLE=The Effects of Nisin-Producing Lactococcus lactis Strain Used as Probiotic on Gilthead Sea Bream (Sparus aurata) Growth, Gut Microbiota, and Transcriptional Response

JOURNAL=Frontiers in Marine Science

VOLUME=Volume 8 - 2021

YEAR=2021

URL=https://www.frontiersin.org/journals/marine-science/articles/10.3389/fmars.2021.659519

DOI=10.3389/fmars.2021.659519

ISSN=2296-7745

ABSTRACT=Studies in which probiotics are administered in fish have yielded positive results; indeed, meta-analyses provide support for a beneficial effect via modulation of gut microbiome. Accordingly, the present research tested the effects of dietary nisin-producing Lactococcus lactis on growth performance, feed utilization, intestinal morphology, transcriptional response, and microbiota in gilthead sea bream (Sparus aurata). The probiotic strain L. lactis subsp. lactis SL242, was isolated from bovine milk. The strain produces nisin A, and it is active against Gram-positive pathogens such as Streptococcus agalactiae, Str. uberis, Str. dysgalactiae, Enterococcus faecalis, Staphylococcus aureus, methicillin-resistant Staphylococcus aureus, and coagulase-negative staphylococci. This property of the strain seemed particularly interesting to us as it fits well with the current pressing