AUTHOR=Agbenyefia Priscilla , Shilliam Lance A. , Stoicea Nicoleta , Roth Andrew , Moran Kenneth R. TITLE=Perioperative Management of a Patient with Cold Urticaria JOURNAL=Frontiers in Medicine VOLUME=Volume 4 - 2017 YEAR=2017 URL=https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2017.00222 DOI=10.3389/fmed.2017.00222 ISSN=2296-858X ABSTRACT=Cold urticaria consists of an allergic immune response to cold temperatures with symptoms ranging from pruritic wheals to life-threatening angioedema, bronchospasm, or anaphylactic shock. Adequate planning to maintain normothermia peri-operatively is vital due to impaired hypothalamic thermoregulation and overall depression of sympathetic outflow during deep sedation and general anesthesia. This case report describes the successful perioperative management of a 45 year-old female with a history of cold urticaria undergoing a laparoscopic Nissen fundoplication for refractory gastroesophageal reflux disease and discusses how to appropriately optimize the care of these patients.