AUTHOR=Kiser Jackson W. , Crowley James R. , Wyatt David A. , Lattanze Ronald K. 

TITLE=Impact of an 18F-FDG PET/CT Radiotracer Injection Infiltration on Patient Management—A Case Report

JOURNAL=Frontiers in Medicine

VOLUME=5

YEAR=2018

URL=https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2018.00143

DOI=10.3389/fmed.2018.00143

ISSN=2296-858X

ABSTRACT=<p>Major management decisions in patients with solid tumors and lymphomas are often based on 18F-fluorodeoxyglucose (18F-FDG) PET/CT. The misadministration of 18F-FDG outside the systemic circulation can have an adverse impact on this test's sensitivity (<xref ref-type="bibr" rid="B1">1</xref>) and is not uncommon (<xref ref-type="bibr" rid="B2">2</xref>–<xref ref-type="bibr" rid="B7">7</xref>). This report describes how an 18F-FDG misadministration led to a repeat PET/CT study, resulting in the visualization of distant metastases that changed the original treatment plan. The findings suggest that routine injection monitoring is indicated whenever sensitivity is critical, and support claims that infiltrations can confound interpretation of semi-quantitative PET outcome measures in patients who are followed longitudinally (<xref ref-type="bibr" rid="B2">2</xref>).</p>