AUTHOR=Kiser Jackson W. , Crowley James R. , Wyatt David A. , Lattanze Ronald K. TITLE=Impact of an 18F-FDG PET/CT Radiotracer Injection Infiltration on Patient Management—A Case Report JOURNAL=Frontiers in Medicine VOLUME=Volume 5 - 2018 YEAR=2018 URL=https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2018.00143 DOI=10.3389/fmed.2018.00143 ISSN=2296-858X ABSTRACT=Major management decisions in patients with solid tumors are often based on Flourine-18 radiolabeled fluorodeoxyglucose (FDG) PET/CT. The misadministration of FDG outside the systemic circulation can have an adverse impact on this test’s sensitivity1 and is not uncommon2 - 7. This report describes how an FDG misadministration led to a repeat PET/CT study, resulting in the visualization of distant metastases that changed the original treatment plan. The findings suggest that routine injection monitoring is indicated whenever sensitivity is critical, and support claims that infiltrations can confound interpretation of semi-quantitative PET outcome measures in patients who are followed longitudinally2.