AUTHOR=Kaneko Shohei , Morino Junki , Minato Saori , Yanai Katsunori , Mutsuyoshi Yuko , Ishii Hiroki , Matsuyama Momoko , Kitano Taisuke , Shindo Mitsutoshi , Aomatsu Akinori , Miyazawa Haruhisa , Ueda Yuichiro , Ito Kiyonori , Hirai Keiji , Ookawara Susumu , Morishita Yoshiyuki 

TITLE=Serum Zinc Concentration Correlates With Ferritin Concentration in Patients Undergoing Peritoneal Dialysis: A Cross-Sectional Study

JOURNAL=Frontiers in Medicine

VOLUME=Volume 7 - 2020

YEAR=2020

URL=https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2020.537586

DOI=10.3389/fmed.2020.537586

ISSN=2296-858X

ABSTRACT=Background: The prevalence and clinical effects of zinc deficiency in patients undergoing peritoneal dialysis (PD) have not been fully established.
Methods: This was a retrospective, cross-sectional study. The prevalence of serum zinc deficiency and the clinical factors related to serum zinc concentration were determined in 49 patients undergoing PD (mean age 59.5 years (± 14.8 years), 38/49 were men (78.6%), median PD period 24.0 months (12.5–45.0 months)). A serum zinc concentration < 60 μg/dL was defined as serum zinc deficiency, and a serum zinc concentration between 60 and 80 μg/dL as possible serum zinc deficiency.
Results: Serum zinc deficiency was present in 51% (25/49) of the patients, and possible serum zinc deficiency was present in 45% (22/49) of patients undergoing PD. Multivariate analysis showed that serum zinc concentration significantly correlated with serum ferritin concentration (β = 0.357, P < 0.01).
Conclusions: The prevalences of serum zinc deficiency and possible serum deficiency are high and serum zinc concentration correlates with serum ferritin concentration in patients undergoing PD.