AUTHOR=Rosińska-Więckowicz Anna , Jałowska Magdalena , Bowszyc-Dmochowska Monika , Dmochowski Marian 

TITLE=Case Report: Infantile Bullous Pemphigoid: Triggering by COVID-19 Is Speculative

JOURNAL=Frontiers in Medicine

VOLUME=Volume 8 - 2021

YEAR=2021

URL=https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2021.760823

DOI=10.3389/fmed.2021.760823

ISSN=2296-858X

ABSTRACT=Bullous pemphigoid (BP) is a cutaneous disease triggering by numerous stimuli, in which genetic milieu-influenced autoimmunity to hemidesmosomal proteins, namely BP180 and /or BP230 initiates an inflammation leading to the dermal-epidermal junction enzymatic pathological remodeling. Here, to the best of our knowledge, we present the first case of an infantile BP apparently triggered by COVID-19. BP should be included in the differential diagnosis of infantile rashes showing blisters or vesicles or both as well as their prodromal and evolutionary lesions. Possible triggers, including COVID-19, of BP in infancy should be identified and properly dealt with.