AUTHOR=Lu Weicong , Ji Rongyuan , Ding Wenzhi , Tian Yuyin , Long Keli , Guo Zhen , Leng Lin 

TITLE=Agreement and Repeatability of Central and Peripheral Refraction by One Novel Multispectral-Based Refractor

JOURNAL=Frontiers in Medicine

VOLUME=Volume 8 - 2021

YEAR=2021

URL=https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2021.777685

DOI=10.3389/fmed.2021.777685

ISSN=2296-858X

ABSTRACT=Purpose: To evaluate the repeatability of multispectral based refractor in central and peripheral refraction measurement, and compare the agreement with objective refraction and subjective refraction of myopia patients.
Methods: A total of 60 subjects were recruited in this prospective research. Patients were divided into three groups according to the refractive error. Next, the central and peripheral refraction parameters were measured using multispectral refractive tomography (MRT) before and after cycloplegia. In addition, the objective and subjective refraction were measured. The intraobserver repeatability was analyzed using within-subject standard deviation (Sw), test–retest repeatability (TRT), and intraclass correlation coefficient (ICC). Furthermore, Bland-Altman plot and 95% limits of agreement (LoA) were adopted for agreement evaluation.
Results: The ICC value of central and peripheral refraction were all above 0.97 with or without cycloplegia. The peripheral refraction of four quadrants was little worse than other parameters, with the largest error interval being 1.43 D. The 95% LoA of central refraction and objective refraction or subjective refraction ranged from -0.89 to 0.88 D and -1.24 to 1.16 D without cycloplegia, and -0.80 to 0.42 D and -1.39 to -0.84D under cycloplegia. 
Conclusions: The novel multispectral refraction topography showed good repeatability in central and peripheral refraction. However, the nasal, temporal, superior, and inferior quadrants were not as good as that of central and circle peripheral refraction.