<?xml version="1.0" encoding="UTF-8" standalone="no"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD Journal Publishing DTD v2.3 20070202//EN" "journalpublishing.dtd">
<article xml:lang="EN" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" article-type="review-article">
<front>
<journal-meta>
<journal-id journal-id-type="publisher-id">Front. Med.</journal-id>
<journal-title>Frontiers in Medicine</journal-title>
<abbrev-journal-title abbrev-type="pubmed">Front. Med.</abbrev-journal-title>
<issn pub-type="epub">2296-858X</issn>
<publisher>
<publisher-name>Frontiers Media S.A.</publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="doi">10.3389/fmed.2022.1010001</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Medicine</subject>
<subj-group>
<subject>Review</subject>
</subj-group>
</subj-group>
</article-categories>
<title-group>
<article-title>Identifying patients with psychosocial problems in general practice: A scoping review</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author" corresp="yes">
<name><surname>Schwenker</surname> <given-names>Rosemarie</given-names></name>
<xref ref-type="aff" rid="aff1"><sup>1</sup></xref>
<xref ref-type="corresp" rid="c001"><sup>&#x002A;</sup></xref>
<uri xlink:href="http://loop.frontiersin.org/people/1936483/overview"/>
</contrib>
<contrib contrib-type="author">
<name><surname>Deutsch</surname> <given-names>Tobias</given-names></name>
<xref ref-type="aff" rid="aff2"><sup>2</sup></xref>
<uri xlink:href="http://loop.frontiersin.org/people/2041200/overview"/>
</contrib>
<contrib contrib-type="author">
<name><surname>Unverzagt</surname> <given-names>Susanne</given-names></name>
<xref ref-type="aff" rid="aff1"><sup>1</sup></xref>
<uri xlink:href="http://loop.frontiersin.org/people/841586/overview"/>
</contrib>
<contrib contrib-type="author">
<name><surname>Frese</surname> <given-names>Thomas</given-names></name>
<xref ref-type="aff" rid="aff1"><sup>1</sup></xref>
</contrib>
</contrib-group>
<aff id="aff1"><sup>1</sup><institution>Center for Health Sciences, Institute of General Practice, Martin-Luther-University Halle-Wittenberg</institution>, <addr-line>Halle (Saale)</addr-line>, <country>Germany</country></aff>
<aff id="aff2"><sup>2</sup><institution>Department of General Practice, University of Leipzig</institution>, <addr-line>Leipzig</addr-line>, <country>Germany</country></aff>
<author-notes>
<fn fn-type="edited-by"><p>Edited by: Ana Claver&#x00ED;a, Instituto de Investigaci&#x00F3;n Sanitaria Galicia Sur (IISGS), Spain</p></fn>
<fn fn-type="edited-by"><p>Reviewed by: Leo Pas, Catholic University Leuven, Belgium; Rosa Magallon, University of Zaragoza, Spain; Patrice Nabbe, Universit&#x00E9; de Bretagne Occidentale, France</p></fn>
<corresp id="c001">&#x002A;Correspondence: Rosemarie Schwenker, <email>rosemarie.schwenker@uk-halle.de</email></corresp>
<fn fn-type="other" id="fn004"><p>This article was submitted to Family Medicine and Primary Care, a section of the journal Frontiers in Medicine</p></fn>
</author-notes>
<pub-date pub-type="epub">
<day>08</day>
<month>02</month>
<year>2023</year>
</pub-date>
<pub-date pub-type="collection">
<year>2022</year>
</pub-date>
<volume>9</volume>
<elocation-id>1010001</elocation-id>
<history>
<date date-type="received">
<day>02</day>
<month>08</month>
<year>2022</year>
</date>
<date date-type="accepted">
<day>21</day>
<month>12</month>
<year>2022</year>
</date>
</history>
<permissions>
<copyright-statement>Copyright &#x00A9; 2023 Schwenker, Deutsch, Unverzagt and Frese.</copyright-statement>
<copyright-year>2023</copyright-year>
<copyright-holder>Schwenker, Deutsch, Unverzagt and Frese</copyright-holder>
<license xlink:href="http://creativecommons.org/licenses/by/4.0/"><p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.</p></license>
</permissions>
<abstract>
<sec>
<title>Objective</title>
<p>We conducted a scoping review with the aim of comprehensively investigating what tools or methods have been examined in general practice research that capture a wide range of psychosocial problems (PSPs) and serve to identify patients and highlight their characteristics.</p>
</sec>
<sec>
<title>Methods</title>
<p>We followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for scoping reviews and the <italic>Joanna Briggs Institute Reviewer&#x2019;s Manual</italic> on scoping reviews. A systematic search was conducted in four electronic databases (Medline [Ovid], Web of Science Core Collection, PsycInfo, Cochrane Library) for quantitative and qualitative studies in English, Spanish, French, and German with no time limit. The protocol was registered with Open Science Framework and published in BMJ Open.</p>
</sec>
<sec>
<title>Results</title>
<p>Of the 839 articles identified, 66 met the criteria for study eligibility, from which 61 instruments were identified. The publications were from 18 different countries, with most studies employing an observational design and including mostly adult patients. Among all instruments, 22 were reported as validated, which we present in this paper. Overall, quality criteria were reported differently, with studies generally providing little detail. Most of the instruments were used as paper and pencil questionnaires. We found considerable heterogeneity in the theoretical conceptualisation, definition, and measurement of PSPs, ranging from psychiatric case findings to specific social problems.</p>
</sec>
<sec>
<title>Discussion and conclusion</title>
<p>This review presents a number of tools and methods that have been studied and used in general practice research. Adapted and tailored to local circumstances, practice populations, and needs, they could be useful for identifying patients with PSPs in daily GP practice; however, this requires further research. Given the heterogeneity of studies and instruments, future research efforts should include both a more structured evaluation of instruments and the incorporation of consensus methods to move forward from instrument research to actual use in daily practice.</p>
</sec>
</abstract>
<kwd-group>
<kwd>primary care</kwd>
<kwd>general practice</kwd>
<kwd>psychosocial problems</kwd>
<kwd>social problems</kwd>
<kwd>identification tools</kwd>
<kwd>scoping review</kwd>
</kwd-group>
<counts>
<fig-count count="1"/>
<table-count count="3"/>
<equation-count count="0"/>
<ref-count count="122"/>
<page-count count="13"/>
<word-count count="10379"/>
</counts>
</article-meta>
</front>
<body>
<sec id="S1" sec-type="intro">
<title>1. Introduction</title>
<p>Since general practitioners (GPs) are usually the first point of contact for people with any health-related concern, patients visit their GP not only for medical reasons but also for psychosocial problems (PSPs) (<xref ref-type="bibr" rid="B1">1</xref>&#x2013;<xref ref-type="bibr" rid="B4">4</xref>). Here we take problems to be &#x201C;a source of perplexity, distress, or vexation&#x201D;, while we take PSPs to refer to problems related to the conditions in which people are born, grow, live, work, and age (<xref ref-type="bibr" rid="B5">5</xref>). These conditions in which people lead their lives have a profound impact on health.</p>
<p>The relationship between these conditions and health has been investigated in numerous studies and addressed in many health reports (<xref ref-type="bibr" rid="B6">6</xref>&#x2013;<xref ref-type="bibr" rid="B9">9</xref>). In a general sense, people with PSPs are vulnerable to negative health outcomes, comorbidities, and have a generally poorer health status (<xref ref-type="bibr" rid="B10">10</xref>), while PSPs are also related to several more specific conditions, such as cardiovascular diseases, diabetes, infectious diseases, and psychiatric disorders (<xref ref-type="bibr" rid="B11">11</xref>&#x2013;<xref ref-type="bibr" rid="B17">17</xref>). This is because PSPs affect immunological and inflammatory processes (<xref ref-type="bibr" rid="B18">18</xref>&#x2013;<xref ref-type="bibr" rid="B20">20</xref>) and are associated with an increased risk of illness, delayed recovery, chronic disease progression, and compromised quality of life and mortality rates (<xref ref-type="bibr" rid="B10">10</xref>, <xref ref-type="bibr" rid="B21">21</xref>&#x2013;<xref ref-type="bibr" rid="B23">23</xref>). As one example, individuals who are socially isolated are at risk of premature mortality, comparable to well-documented risk factors, such as smoking and obesity (<xref ref-type="bibr" rid="B11">11</xref>, <xref ref-type="bibr" rid="B24">24</xref>&#x2013;<xref ref-type="bibr" rid="B27">27</xref>). Furthermore, psychosocial factors at work have been shown to be associated with a range of health outcomes, such as job strain and increased risk for heart disease or diabetes (<xref ref-type="bibr" rid="B28">28</xref>&#x2013;<xref ref-type="bibr" rid="B31">31</xref>). Similarly, job insecurity and unemployment have been found to be associated with an increased risk for cardiovascular and coronary heart disease (<xref ref-type="bibr" rid="B32">32</xref>).</p>
<p>The issue of PSPs in general practice began to draw greater attention in the 1990s (<xref ref-type="bibr" rid="B33">33</xref>&#x2013;<xref ref-type="bibr" rid="B35">35</xref>) and a vast body of research has investigated their significance since then. For instance, studies show that at least one third of patients under general practice report experiencing PSPs and that GPs are consulted by patients with PSPs at least three times per week (<xref ref-type="bibr" rid="B3">3</xref>, <xref ref-type="bibr" rid="B33">33</xref>, <xref ref-type="bibr" rid="B36">36</xref>). Studies most frequently identified family problems, caregiving tasks, violence-related issues, isolation, financial problems, employment problems, problems with physical functioning, and legal problems (<xref ref-type="bibr" rid="B3">3</xref>, <xref ref-type="bibr" rid="B35">35</xref>, <xref ref-type="bibr" rid="B37">37</xref>&#x2013;<xref ref-type="bibr" rid="B46">46</xref>). The most frequently occurring social problems encountered in the primary care context are captured in the International Classification of Primary Care (ICPC-2) (<xref ref-type="bibr" rid="B47">47</xref>). However, studies also show that GPs only correctly identify a fifth to a half of patients with relevant PSPs and that social factors are not considered to have much importance (<xref ref-type="bibr" rid="B37">37</xref>, <xref ref-type="bibr" rid="B48">48</xref>). Possible consequences, such as inadequate diagnoses, non-specific or no intervention or treatment at all, and ineffective use of time have also been extensively described (<xref ref-type="bibr" rid="B2">2</xref>, <xref ref-type="bibr" rid="B34">34</xref>, <xref ref-type="bibr" rid="B35">35</xref>, <xref ref-type="bibr" rid="B37">37</xref>, <xref ref-type="bibr" rid="B40">40</xref>, <xref ref-type="bibr" rid="B41">41</xref>, <xref ref-type="bibr" rid="B43">43</xref>, <xref ref-type="bibr" rid="B44">44</xref>, <xref ref-type="bibr" rid="B49">49</xref>&#x2013;<xref ref-type="bibr" rid="B55">55</xref>).</p>
<p>The complexity and heterogeneity around PSPs leads to difficulties in providing or referring to a universally valid concept. This is compounded by the fact that several disciplines, organisations outside the academic context, and policy makers use different concepts, which in turn leads to difficulties in developing or using a practical approach in the form of a systematic and structured instrument to identify patients with PSPs. This is reflected in the official guidelines of medical organisations or societies and official health organisations, where the integration of the psychosocial perspective into medicine is widely demanded, but concrete steps for practice are still lacking (<xref ref-type="bibr" rid="B3">3</xref>, <xref ref-type="bibr" rid="B10">10</xref>, <xref ref-type="bibr" rid="B55">55</xref>&#x2013;<xref ref-type="bibr" rid="B58">58</xref>).</p>
<p>GPs are in a unique position to take preventive action to promote health and to identify and treat emerging health problems early in routine care. The use of tools to identify patients with PSPs could be useful in this regard. With this in mind, the aim of our study is to provide an overview of the published research in which we present what tools or methods have been studied so far in general practice research that capture a wide range of PSPs and could be used to identify patients presenting with PSPs.</p>
</sec>
<sec id="S2">
<title>2. Methods</title>
<p>We conducted a scoping review by following the <italic>Joanna Briggs Institute Reviewer&#x2019;s Manual</italic> (<xref ref-type="bibr" rid="B59">59</xref>) and the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews checklist (<xref ref-type="bibr" rid="B60">60</xref>). A protocol has been registered with Open Science Framework (OSF) (<xref ref-type="bibr" rid="B61">61</xref>) and published in BMJ Open (<xref ref-type="bibr" rid="B62">62</xref>). Since the entire review process with its individual phases is iterative and fundamentally a process of developing understanding, hermeneutic principles were applied consisting of two mutually influencing cycles; searching and accessing the literature, and analysis and interpretation (<xref ref-type="bibr" rid="B63">63</xref>).</p>
<p>The review process was conducted in an intersubjective manner as part of the collaborative research process. Collaboration provides a check and balance through which an analytical consensus can be reached that allows for a more comprehensive interpretation and for the group analysis to move beyond individually preconceived perspectives. Through the process of multiple researchers articulating, clarifying, and challenging their initial interpretations, consensus was reached on which studies should be included, which represented the relevant information for extraction, and how they should be summarised and classified (<xref ref-type="bibr" rid="B64">64</xref>).</p>
<sec id="S2.SS1">
<title>2.1. Inclusion criteria</title>
<p>Evidence sources were considered for inclusion if they met the criteria specified by the JBI based on the population, concept, and context framework (<xref ref-type="bibr" rid="B59">59</xref>) (<xref ref-type="table" rid="T1">Table 1</xref>). Included evidence sources were required</p>
<table-wrap position="float" id="T1">
<label>TABLE 1</label>
<caption><p>Eligibility criteria based on study population, context, concept, and types of sources of evidence.</p></caption>
<table cellspacing="5" cellpadding="5" frame="box" rules="all">
<thead>
<tr>
<td valign="top" align="left" style="color:#ffffff;background-color: #7f8080;"/>
<td valign="top" align="left" style="color:#ffffff;background-color: #7f8080;">Inclusion criteria</td>
<td valign="top" align="left" style="color:#ffffff;background-color: #7f8080;">Exclusion criteria</td>
</tr>
</thead>
<tbody>
<tr>
<td valign="top" align="left" style="color:#ffffff;background-color: #7f8080;"><bold>Population</bold></td>
<td valign="top" align="left">&#x2022; Adolescents, adults, or elderly people</td>
<td valign="top" align="left">&#x2022; Adolescents, adults, or elderly people with disease-specific PSPs related to, e.g., cancer, HIV, diabetes, substance use disorder, or psychiatric disorders</td>
</tr>
<tr>
<td valign="top" align="left" style="color:#ffffff;background-color: #7f8080;"><bold>Concept</bold></td>
<td valign="top" align="left">&#x2022; Any kind of instrument or approach (e.g., questionnaire, interview) to identify patients with PSPs in general or regarding specific social problems according to ICPC-2, Section Z<xref ref-type="table-fn" rid="t1fn2"><sup>2</sup></xref>, and any kind of reporting format (e.g., self-reported, physicians&#x2019; assessment)</td>
<td valign="top" align="left">&#x2022; Identification instruments or approaches based on the report of patients&#x2019; parents, carers, or other significant others</td>
</tr>
<tr>
<td valign="top" align="left" style="color:#ffffff;background-color: #7f8080;"><bold>Context</bold></td>
<td valign="top" align="left">&#x2022; General practice settings<break/>&#x2022; Any geographical location</td>
<td/>
</tr>
<tr>
<td valign="top" align="left" style="color:#ffffff;background-color: #7f8080;"><bold>Types of sources of evidence</bold></td>
<td valign="top" align="left">&#x2022; Peer-reviewed publications<break/>&#x2022; Primary empirical research studies (e.g., quantitative, qualitative, or mixed-methods studies)<break/>&#x2022; Theoretical articles describing an instrument used for identifying patients with PSPs in sufficient detail<break/>&#x2022; Full-text publications according to the EQUATOR Network (<xref ref-type="bibr" rid="B60">60</xref>) guidelines<break/>&#x2022; Articles written in English, Spanish, French, or German, without time restriction</td>
<td valign="top" align="left">&#x2022; Editorial articles (e.g., perspective pieces, opinion papers, position statements)<break/>&#x2022; Study protocols<break/>&#x2022; Abstracts and posters<break/>&#x2022; Author replies/comments<break/>&#x2022; Dissertations/theses<break/>&#x2022; Articles for which we could not obtain the full text or that are not written in English, Spanish, French, or German</td>
</tr>
<tr>
<td valign="top" align="left" colspan="3">EQUATOR, Enhancing the QUAlity and Transparency Of health Research; PSPs, psychosocial problems</td>
</tr>
</tbody>
</table>
<table-wrap-foot>
<fn id="t1fn2"><p><sup>2</sup>Poverty/financial problem (Z01), Food/water problem (Z02), Housing/neighbourhood problem (Z03), Social cultural problem (Z04), Work problem (Z05), Unemployment problem (Z06), Education problem (Z07), Social welfare problem (Z08), Legal problem (Z09), Health care system problem (Z10), Compliance/being ill problem (Z11), Relationship problem with partner (Z12), Partner&#x2019;s behaviour problem (Z13), Partner illness problem (Z14), Loss/death of partner problem (Z15), Relationship problem with child (Z16), Illness problem with child.</p></fn>
</table-wrap-foot>
</table-wrap>
<list list-type="simple">
<list-item>
<label>(1)</label>
<p>to refer to the adolescent, adult, or elderly population in general practice settings and</p>
</list-item>
<list-item>
<label>(2)</label>
<p>to describe any kind of tool or approach to identify patients with PSPs.</p>
</list-item>
</list>
<p>We took into consideration articles that included PSPs in general, as well as articles that focused on specific social problems according to the ICPC-2. As the term &#x201C;psychosocial problems&#x201D; is used very differently and inconsistently in different publications and even within the same publication, no strict definition was set as an inclusion criterion and therefore we also included publications that refer to PSPs but were labelled as, for example, &#x201C;mental health problems,&#x201D; &#x201C;psychological distress,&#x201D; or &#x201C;emotional stress.&#x201D; This approach was taken to ensure that the descriptions in the articles identified in the search could use any definition of PSPs and still be included. However, we wanted the &#x201C;social&#x201D; aspect to be present and were particularly interested in tools that focus on assessing patients&#x2019; problems rather than making a formal diagnosis. This process was carried out through an independent review of the full texts by two reviewers and consensus building when conflicts arose.</p>
<p>In line with the characteristics of a scoping review, all types of empirical research studies were included (<xref ref-type="bibr" rid="B59">59</xref>). Not all articles reported studies. In those cases where no study was reported, but an instrument or approach for identifying patients with PSPs was described in sufficient detail, the articles were included. The search was limited to references published in English, Spanish, French, and German, without time restriction, and from any geographical location. We excluded articles in which the population described consisted of patients with PSPs related to specific chronic diseases or conditions (e.g., cancer, HIV, diabetes, substance use, or psychiatric disorders) as there are specific research areas for these and their inclusion would have been beyond the scope of our study and inconsistent with our focus on the general population. We also excluded studies where the identification tools or approaches were based on reports from third parties, (e.g., parents), rather than from the participants themselves or a healthcare professional.</p>
</sec>
<sec id="S2.SS2">
<title>2.2. Search strategy</title>
<p>A preliminary search was conducted in MEDLINE (Ovid) database to gain familiarity and an overview and to identify key terms. We developed a search strategy for MEDLINE (Ovid) (see <xref ref-type="supplementary-material" rid="TS1">Supplementary Table 1</xref>) and adapted this strategy to the databases PsycInfo, the Cochrane Library, and the Web of Science Core Collection. The search took place from March to April 2021. We hand-searched and screened the reference lists of the included evidence sources to identify other potential references. We screened the reference lists of systematic reviews and scoping reviews which examined studies potentially fitting our inclusion criteria for further relevant articles. Search results were exported into EndNote 20. After elimination of duplicates, the remaining references were uploaded to Covidence for screening and data extraction. An updated search was performed in June 2022.</p>
</sec>
<sec id="S2.SS3">
<title>2.3. Source of evidence screening and selection</title>
<p>Two reviewers (RS, TD) independently screened the references by title and abstract. The full texts of selected articles were then retrieved and fully read by the same two reviewers. In both steps, discrepancies between reviewers&#x2019; assessments were discussed and solved by consensus. A list of included studies is presented in <xref ref-type="supplementary-material" rid="TS2">Supplementary Table 2</xref>.</p>
</sec>
<sec id="S2.SS4">
<title>2.4. Data extraction</title>
<p>A data extraction template was devised by the primary author (RS) to capture information relevant to the research question (see <xref ref-type="supplementary-material" rid="TS3">Supplementary Table 3</xref>). Two reviewers (RS, TD) independently performed a pilot data extraction on a random sample of five articles and subsequently refined the form. Data extraction was conducted independently by RS and a study assistant who met frequently with TD to discuss the process and refine the data extraction form to ensure that all information relevant to answering the research question was extracted from the publications. Reviewers extracted findings as reported, in the form of numerical or narrative summary statements. Disagreements were resolved through consensus building and, if necessary, by involving a third reviewer.</p>
</sec>
<sec id="S2.SS5">
<title>2.5. Data synthesis and analysis</title>
<p>Following data extraction, each study was categorised according to year of publication, country, setting, research design, population, and the tool(s) or method(s) described (see <xref ref-type="supplementary-material" rid="TS4">Supplementary Table 4</xref>). A narrative of the data was then developed.</p>
</sec>
<sec id="S2.SS6">
<title>2.6. Deviations from the protocol</title>
<p>As there are not only studies but also publications that describe schemes, frameworks, or instruments to theoretically identify patients with PSPs, we decided to refine our inclusion criteria accordingly. For articles reporting Randomised Controlled Trials (RCTs), we decided to include not only identification tools, which were mostly used to recruit study participants, but also outcome assessment tools if they met our inclusion criteria. The original data extraction form proposed in the protocol was modified during the pilot data extraction phase in order to capture the most relevant aspects of the included articles.</p>
</sec>
</sec>
<sec id="S3" sec-type="results">
<title>3. Results</title>
<sec id="S3.SS1">
<title>3.1. Study selection</title>
<p>The searches of electronic databases resulted in 839 records. After removing duplicates, a total of 794 titles and abstracts were screened, from which 669 articles were removed, with 125 articles then subjected to a full-text review. In this step, a further 6 additional records were identified through references from identified articles. Of the full-text articles reviewed, 59 were excluded. This left 66 studies that were considered eligible for inclusion and from which relevant information was extracted. <xref ref-type="fig" rid="F1">Figure 1</xref> presents the PRISMA flow diagram. Reasons for exclusion are reported in <xref ref-type="supplementary-material" rid="TS5">Supplementary Table 5</xref>.</p>
<fig id="F1" position="float">
<label>FIGURE 1</label>
<caption><p>PRISMA flow diagram.</p></caption>
<graphic mimetype="image" mime-subtype="tiff" xlink:href="fmed-09-1010001-g001.tif"/>
</fig>
</sec>
<sec id="S3.SS2">
<title>3.2. Study characteristics</title>
<p><xref ref-type="supplementary-material" rid="TS4">Supplementary Table 4</xref> presents the general study characteristics of the 66 studies included in this review. The articles included were published between 1978 and 2020. We identified a total of 61 instruments. In this paper, we present only validated instruments (22). Results for the remaining instruments without validation will be published separately.</p>
<sec id="S3.SS2.SSS1">
<title>3.2.1. Context (country and setting)</title>
<p>We identified publications from 18 countries, with the most deriving from the United Kingdom (13), the Netherlands (9), the United States (7), Australia (7), and New Zealand (5). There is a clear concentration of studies conducted in Europe (39), followed by Australasia (12), and North America (9). Of the 66 included studies, 64 come from high-income countries, with 1 article each from an upper-middle income country (Brazil) and a lower-middle income country (Pakistan).</p>
<p>All publications referred to a general practice setting. However, our study allowed for different regional uses of terms. This means that the studied context is not only referred to as general practice (41), but also as primary care (15) and family medicine (8), while the terms general internal medicine (1) and health care centre (1) were also used.</p>
</sec>
<sec id="S3.SS2.SSS2">
<title>3.2.2. Research design</title>
<p>Most of the studies included were analytical (62). Among these, observational studies were the most common (42), such as cross-sectional studies and prospective studies, followed by experimental studies (12), such as (cluster) randomised controlled trials (RCTs). Descriptive studies were also included, such as narrative/literature reviews (4). No qualitative studies were identified.</p>
</sec>
<sec id="S3.SS2.SSS3">
<title>3.2.3. Population</title>
<p>Publications included in this review focused mostly on adults (49), with others focused on elderly people (10) and on adolescents and/or young people (7). Specific characteristics among the adult population refer to pregnant women (1), veterans (1), caregivers of patients with a chronic condition (1), and people classified as lesbian, gay, or bisexual (1). Almost half of the studies included patients (31), with others focused on caregivers (1) and citizens (2), while the other half worked with patients and physicians and/or practice nurses/staff, and/or community mental health nurses (31). One article focused only on physicians. Study samples show a higher proportion of those identified as of biologically female sex.</p>
</sec>
</sec>
<sec id="S3.SS3">
<title>3.3. Instrument characteristics</title>
<p>Of the 66 articles, 48 used 1 instrument, 8 publications used 2 instruments, and 10 articles used 3 or more instruments that met our inclusion criteria. <xref ref-type="table" rid="T2">Table 2</xref> shows the characteristics of the instruments in terms of instrument name, study, stated focus, and age group. <xref ref-type="table" rid="T3">Table 3</xref> contains further aspects, such as screening setting, type of instrument, screening method, mode of administration, regularity of screening, and whether and what information on quality criteria were assessed. In total, 61 instruments or methods were identified. Of these, 22 were reported as validated and are presented below.</p>
<table-wrap position="float" id="T2">
<label>TABLE 2</label>
<caption><p>Instrument characteristics.</p></caption>
<table cellspacing="5" cellpadding="5" frame="box" rules="all">
<thead>
<tr>
<td valign="top" align="left" style="color:#ffffff;background-color: #7f8080;">Instrument</td>
<td valign="top" align="left" style="color:#ffffff;background-color: #7f8080;">Study</td>
<td valign="top" align="left" style="color:#ffffff;background-color: #7f8080;">Focus of instrument reported in the study</td>
<td valign="top" align="left" style="color:#ffffff;background-color: #7f8080;">Age group</td>
</tr>
</thead>
<tbody>
<tr>
<td valign="top" align="left" colspan="4" style="background-color: #dcdcdc;"><bold>Thematic pattern I: Comprehensive (medical, psychological and/or psychosocial and/or social aspects)</bold></td>
</tr>
<tr>
<td valign="top" align="left">Adapted General Well-Being Index (AGWBI)<xref ref-type="table-fn" rid="t2fns1">&#x002A;</xref></td>
<td valign="top" align="left">Hopton (<xref ref-type="bibr" rid="B87">87</xref>)</td>
<td valign="top" align="left">Experience of illness, distress and psychosocial difficulties: anxiety, depression, positive wellbeing, general health perceptions, vitality, and perceptions of self-control; common worries or difficulties: relationship, partner, money, housing, work, social activities, unemployment, children, family members, violence/threat of violence, death of a close person</td>
<td valign="top" align="left">Adults</td>
</tr>
<tr>
<td valign="top" align="left">Case-finding and Help Assessment Tool (CHAT)<xref ref-type="table-fn" rid="t2fns1">&#x002A;</xref></td>
<td valign="top" align="left">Goodyear-Smith (<xref ref-type="bibr" rid="B88">88</xref>, <xref ref-type="bibr" rid="B68">68</xref>)</td>
<td valign="top" align="left">Lifestyle and mental health assessment: tobacco use, alcohol and other drug misuse, problem gambling, depression, anxiety and stress, abuse, anger problems, inactivity, eating disorders, insomnia</td>
<td valign="top" align="left">Adults</td>
</tr>
<tr>
<td valign="top" align="left">Coding System for Primary Health Care (CPHC)<xref ref-type="table-fn" rid="t2fns1">&#x002A;</xref></td>
<td valign="top" align="left">Deli&#x00E8;ge (<xref ref-type="bibr" rid="B89">89</xref>)</td>
<td valign="top" align="left">Social problems and complaints: family problems, social integration problems, socio-economic problems and basic needs, problems of social status and occupation, problems with social institutions, problems of violence in society, functional and social consequences of diseases, other problems</td>
<td valign="top" align="left">Adults</td>
</tr>
<tr>
<td valign="top" align="left">Electronic Case-finding and Help Assessment Tool (eCHAT)</td>
<td valign="top" align="left">Goodyear-Smith (<xref ref-type="bibr" rid="B90">90</xref>)</td>
<td valign="top" align="left">Lifestyle risk factors: smoking, problematic drinking, other drug use, gambling, exposure to abuse, physical inactivity; mental health issues: depression, anxiety, anger control</td>
<td valign="top" align="left">Adults</td>
</tr>
<tr>
<td valign="top" align="left">Multifactor Health Inventory (MHI)</td>
<td valign="top" align="left">Hase and Luger (<xref ref-type="bibr" rid="B91">91</xref>)</td>
<td valign="top" align="left">Symptoms and problems: physical symptoms and possible psychological and behavioural problems, attitudes</td>
<td valign="top" align="left">Adults</td>
</tr>
<tr>
<td valign="top" align="left">Observation List for Mental Disorders and Social Problems (OLP)</td>
<td valign="top" align="left">Tak (<xref ref-type="bibr" rid="B92">92</xref>)</td>
<td valign="top" align="left">Mental disorders and social problems: anxiety, depression, cognitive impairment, suspicion, loneliness, somatisation</td>
<td valign="top" align="left">Elderly people</td>
</tr>
<tr>
<td valign="top" align="left">Personal Inventory</td>
<td valign="top" align="left">Hilliard (<xref ref-type="bibr" rid="B93">93</xref>)</td>
<td valign="top" align="left">Psychological functioning: quality of intimate relationships, emotional distress, concerns about employment and finances, personal energy, coping</td>
<td valign="top" align="left">Adults</td>
</tr>
<tr>
<td valign="top" align="left">Short Form Health Survey (SF-12)<xref ref-type="table-fn" rid="t2fns1">&#x002A;</xref></td>
<td valign="top" align="left">King (<xref ref-type="bibr" rid="B94">94</xref>)/Schreuders (<xref ref-type="bibr" rid="B95">95</xref>)/MacMillan (<xref ref-type="bibr" rid="B67">67</xref>)/Freund and Lous (<xref ref-type="bibr" rid="B65">65</xref>)/Hegarty (<xref ref-type="bibr" rid="B96">96</xref>)/Geyti (<xref ref-type="bibr" rid="B79">79</xref>, <xref ref-type="bibr" rid="B97">97</xref>)</td>
<td valign="top" align="left">Physical and psychological well-being/Global mental and physical health and well-being/Health-related quality of life/Mental health status/General health, mental health, and health behaviour, mood and anxiety symptoms, physical health, functional limitations/Mental health status, health-related quality of life</td>
<td valign="top" align="left">Adults</td>
</tr>
<tr>
<td valign="top" align="left">Short Form-36 (SF-36)<xref ref-type="table-fn" rid="t2fns1">&#x002A;</xref></td>
<td valign="top" align="left">Raine (<xref ref-type="bibr" rid="B98">98</xref>)/Schreuders (<xref ref-type="bibr" rid="B95">95</xref>)/Hassink-Franke (<xref ref-type="bibr" rid="B99">99</xref>)</td>
<td valign="top" align="left">Social functioning, mental health, role limitation due to emotional problems, general health perception/Physical functioning, role limitations due to mental health problems, bodily pain, general health perceptions, vitality, social functioning, role limitations due to emotional problems and general mental health/Physical and mental health</td>
<td valign="top" align="left">Adults</td>
</tr>
<tr>
<td valign="top" align="left" colspan="4" style="background-color: #dcdcdc;"><bold>Thematic pattern II: One or more social problem(s)</bold></td>
</tr>
<tr>
<td valign="top" align="left">Composite Abuse Scale (CAS)<xref ref-type="table-fn" rid="t2fns1">&#x002A;</xref></td>
<td valign="top" align="left">MacMillan (<xref ref-type="bibr" rid="B67">67</xref>)/Sanci (<xref ref-type="bibr" rid="B100">100</xref>)</td>
<td valign="top" align="left">Intimate partner violence and physical, sexual, and emotional abuse in the last 12 months</td>
<td valign="top" align="left">Adults</td>
</tr>
<tr>
<td valign="top" align="left">Family APGAR<xref ref-type="table-fn" rid="t2fns1">&#x002A;</xref></td>
<td valign="top" align="left">Hilliard (<xref ref-type="bibr" rid="B93">93</xref>)/De la Revilla (<xref ref-type="bibr" rid="B101">101</xref>)</td>
<td valign="top" align="left">Family functioning: adaptation, partnership, growth, affection, and resolve</td>
<td valign="top" align="left">Adults</td>
</tr>
<tr>
<td valign="top" align="left">Family Strain Questionnaire Short Form (FSQ-SF)<xref ref-type="table-fn" rid="t2fns1">&#x002A;</xref></td>
<td valign="top" align="left">Vidotto (<xref ref-type="bibr" rid="B102">102</xref>)</td>
<td valign="top" align="left">Emotional burden, problems in social involvement, need for knowledge about the disease, satisfaction with family relationships, thoughts about death</td>
<td valign="top" align="left">Adults</td>
</tr>
<tr>
<td valign="top" align="left">Hopkins-Symptom Checklist (HSCL-25)</td>
<td valign="top" align="left">Stefansson and Svensson (<xref ref-type="bibr" rid="B103">103</xref>)</td>
<td valign="top" align="left">Social problems: work, financial, childcare, housing, social isolation</td>
<td valign="top" align="left">Adults</td>
</tr>
<tr>
<td valign="top" align="left">Patient Health Survey</td>
<td valign="top" align="left">Wasson (<xref ref-type="bibr" rid="B104">104</xref>)</td>
<td valign="top" align="left">Abusive relationships/Domestic abuse: problems in the household that led to insulting/swearing, yelling, threatening, hitting/pushing</td>
<td valign="top" align="left">Adults</td>
</tr>
<tr>
<td valign="top" align="left">Social Needs Checklist (SNC)</td>
<td valign="top" align="left">Cook (<xref ref-type="bibr" rid="B105">105</xref>)</td>
<td valign="top" align="left">Social and environmental problems: finances, personal stress, family problems, legal, employment or career issue, transportation, too much time alone, activities of daily living, shopping, laundry or house cleaning, other needs, cooking, home health care, housing, obtaining nursing home placement</td>
<td valign="top" align="left">Adults</td>
</tr>
<tr>
<td valign="top" align="left">Social Problem Questionnaire (SPQ)</td>
<td valign="top" align="left">Al-Shammari (<xref ref-type="bibr" rid="B106">106</xref>)/Saltini (<xref ref-type="bibr" rid="B107">107</xref>)</td>
<td valign="top" align="left">Social problems: housing, work, finances, social activities, marital, children, other domestic relationship, relationship with others (e.g., extended family)/Social problems (financial, housing, occupational, social/marital relationship)</td>
<td valign="top" align="left">Adults</td>
</tr>
<tr>
<td valign="top" align="left" colspan="4" style="background-color: #dcdcdc;"><bold>Thematic pattern III: Psychological aspects</bold></td>
</tr>
<tr>
<td valign="top" align="left">Four-Dimensional Symptom Questionnaire (4DSQ)<xref ref-type="table-fn" rid="t2fns1">&#x002A;</xref></td>
<td valign="top" align="left">Terluin (<xref ref-type="bibr" rid="B108">108</xref>)</td>
<td valign="top" align="left">Common psychological symptoms, distinguish non-specific general distress from depression, anxiety and somatisation; distress: worry, irritability, tension, listlessness, poor concentration, sleeping problems, demoralisation</td>
<td valign="top" align="left">Adults</td>
</tr>
<tr>
<td valign="top" align="left">General Health Questionnaire (GHQ-12) <xref ref-type="table-fn" rid="t2fns1">&#x002A;</xref></td>
<td valign="top" align="left">Van der Pasch and Verhaak (<xref ref-type="bibr" rid="B109">109</xref>)/Kapur (<xref ref-type="bibr" rid="B110">110</xref>)/Saltini (<xref ref-type="bibr" rid="B107">107</xref>)/Kendrick (<xref ref-type="bibr" rid="B111">111</xref>)/Mirza (<xref ref-type="bibr" rid="B112">112</xref>)/King (<xref ref-type="bibr" rid="B94">94</xref>)/Schreuders (<xref ref-type="bibr" rid="B95">95</xref>)/Goncalves (<xref ref-type="bibr" rid="B113">113</xref>)/Hassink-Franke (<xref ref-type="bibr" rid="B99">99</xref>)</td>
<td valign="top" align="left">Psychosocial complaints (common mental disorders); reason for the visit, onset of their problem, name of problem, problem severity, what to fear most about problem, activities and functioning (difficulties), affect on body parts/Psychological distress/Mental health problems/Common mental disorders/Emotional distress/Current mental health problems/Emotional symptoms</td>
<td valign="top" align="left">Adults</td>
</tr>
<tr>
<td valign="top" align="left">General Health Questionnaire (GHQ-28) <xref ref-type="table-fn" rid="t2fns1">&#x002A;</xref></td>
<td valign="top" align="left">Shiber (<xref ref-type="bibr" rid="B114">114</xref>)/De la Revilla (<xref ref-type="bibr" rid="B101">101</xref>)/Raine (<xref ref-type="bibr" rid="B98">98</xref>)/Watts (<xref ref-type="bibr" rid="B115">115</xref>)/De la Revilla Ahumada (<xref ref-type="bibr" rid="B116">116</xref>)/Rabinowitz (<xref ref-type="bibr" rid="B117">117</xref>)</td>
<td valign="top" align="left">Emotional problems/Psychosocial problems: somatic symptoms of psychological origin, distress/anxiety, social dysfunction and depression/Mental health problems/Psychosocial problems: somatic symptoms, distress/anxiety, social dysfunction and depression/Psychological distress: somatic symptoms (e.g., feeling run-down), anxiety/insomnia (e.g., lost sleep over worry), social dysfunction (e.g., taking longer over things), and severe depression (e.g., life not worth living)/Psychological problems</td>
<td valign="top" align="left">Adults; Elderly people</td>
</tr>
<tr>
<td valign="top" align="left">General Health Questionnaire (GHQ-30)</td>
<td valign="top" align="left">Verhaak (<xref ref-type="bibr" rid="B118">118</xref>, <xref ref-type="bibr" rid="B119">119</xref>)/Odell (<xref ref-type="bibr" rid="B120">120</xref>)/Smith (<xref ref-type="bibr" rid="B66">66</xref>)</td>
<td valign="top" align="left">Physical, psychological, social problems, emotional distress/Psychiatric morbidity/Mental disorders</td>
<td valign="top" align="left">Adults</td>
</tr>
<tr>
<td valign="top" align="left">General Health Questionnaire (GHQ-60)</td>
<td valign="top" align="left">Corser (<xref ref-type="bibr" rid="B121">121</xref>)</td>
<td valign="top" align="left">Emotional state, psychological complaints</td>
<td valign="top" align="left">Adults</td>
</tr>
<tr>
<td valign="top" align="left">Strengths and Difficulties Questionnaire (SDQ)<xref ref-type="table-fn" rid="t2fns1">&#x002A;</xref></td>
<td valign="top" align="left">Martinez (<xref ref-type="bibr" rid="B122">122</xref>)</td>
<td valign="top" align="left">Psychological difficulties: overall distress, social impairment, burden and chronicity of the problem</td>
<td valign="top" align="left">Adolescents</td>
</tr>
</tbody>
</table>
<table-wrap-foot>
<fn id="t2fns1"><p>Q, Questionnaire; I, Interview; M, Mnemonic; &#x002A;Freely available.</p></fn>
</table-wrap-foot>
</table-wrap>
<table-wrap position="float" id="T3">
<label>TABLE 3</label>
<caption><p>Instrument characteristics in detail.</p></caption>
<table cellspacing="5" cellpadding="5" frame="box" rules="all">
<thead>
<tr>
<td valign="top" align="left" style="color:#ffffff;background-color: #7f8080;">Instrument</td>
<td valign="top" align="left" style="color:#ffffff;background-color: #7f8080;">Screening setting</td>
<td valign="top" align="left" style="color:#ffffff;background-color: #7f8080;">Type of instrument</td>
<td valign="top" align="left" style="color:#ffffff;background-color: #7f8080;">Screening method</td>
<td valign="top" align="left" style="color:#ffffff;background-color: #7f8080;">Administered by</td>
<td valign="top" align="left" style="color:#ffffff;background-color: #7f8080;">Regularity of screening</td>
<td valign="top" align="left" colspan="3" style="color:#ffffff;background-color: #7f8080;">Information on</td>
</tr>
<tr>
<td valign="top" align="left" style="color:#ffffff;background-color: #7f8080;"/>
<td valign="top" align="left" style="color:#ffffff;background-color: #7f8080;"/>
<td valign="top" align="left" style="color:#ffffff;background-color: #7f8080;"/>
<td valign="top" align="left" style="color:#ffffff;background-color: #7f8080;"/>
<td valign="top" align="left" style="color:#ffffff;background-color: #7f8080;"/>
<td valign="top" align="left" style="color:#ffffff;background-color: #7f8080;"/>
<td valign="top" align="left" style="color:#ffffff;background-color: #7f8080;">Validity</td>
<td valign="top" align="left" style="color:#ffffff;background-color: #7f8080;">Reliability</td>
<td valign="top" align="left" style="color:#ffffff;background-color: #7f8080;">Feasibility</td>
</tr>
</thead>
<tbody>
<tr>
<td valign="top" align="left" colspan="9" style="background-color: #dcdcdc;"><bold>Thematic pattern I: Comprehensive (medical, psychological and/or psychosocial and/or social aspects)</bold></td>
</tr>
<tr>
<td valign="top" align="left">Adapted General Well-Being Index (AGWBI)<xref ref-type="table-fn" rid="t3fns1">&#x002A;</xref></td>
<td valign="top" align="left">NR</td>
<td valign="top" align="left">Q</td>
<td valign="top" align="left">Paper and pencil</td>
<td valign="top" align="left">Patient</td>
<td valign="top" align="left">NR</td>
<td valign="top" align="left">Assessed in the study</td>
<td valign="top" align="left">Yes</td>
<td valign="top" align="left">NR</td>
</tr>
<tr>
<td valign="top" align="left">Case-finding and Help Assessment Tool (CHAT)<xref ref-type="table-fn" rid="t3fns1">&#x002A;</xref></td>
<td valign="top" align="left">In the waiting room, prior to consultation</td>
<td valign="top" align="left">Q</td>
<td valign="top" align="left">Paper and pencil</td>
<td valign="top" align="left">Patient</td>
<td valign="top" align="left">NR</td>
<td valign="top" align="left">Assessed in the study</td>
<td valign="top" align="left">Yes/NR</td>
<td valign="top" align="left">2 min. to complete</td>
</tr>
<tr>
<td valign="top" align="left">Coding System for Primary Health Care (CPHC)<xref ref-type="table-fn" rid="t3fns1">&#x002A;</xref></td>
<td valign="top" align="left">NR</td>
<td valign="top" align="left">Classification system, conceptual framework</td>
<td valign="top" align="left">NR</td>
<td valign="top" align="left">Physician</td>
<td valign="top" align="left">NR</td>
<td valign="top" align="left">Yes</td>
<td valign="top" align="left">Yes</td>
<td valign="top" align="left">NR</td>
</tr>
<tr>
<td valign="top" align="left">Electronic Case-finding and Help Assessment Tool (eCHAT)</td>
<td valign="top" align="left">In the waiting room, prior to consultation</td>
<td valign="top" align="left">Q</td>
<td valign="top" align="left">Computer or tablet</td>
<td valign="top" align="left">Patient</td>
<td valign="top" align="left">NR</td>
<td valign="top" align="left">Yes</td>
<td valign="top" align="left">NR</td>
<td valign="top" align="left">Yes</td>
</tr>
<tr>
<td valign="top" align="left">Multifactor Health Inventory (MHI)</td>
<td valign="top" align="left">In the waiting room, consultation room</td>
<td valign="top" align="left">Q</td>
<td valign="top" align="left">Paper and pencil</td>
<td valign="top" align="left">Patient</td>
<td valign="top" align="left">NR</td>
<td valign="top" align="left">External validity</td>
<td valign="top" align="left">Stability</td>
<td valign="top" align="left">10 min. to complete</td>
</tr>
<tr>
<td valign="top" align="left">Observation List for Mental Disorders and Social Problems (OLP)</td>
<td valign="top" align="left">NR</td>
<td valign="top" align="left">Q</td>
<td valign="top" align="left">Paper and pencil</td>
<td valign="top" align="left">Physician, home care worker</td>
<td valign="top" align="left">After observation in regular visit</td>
<td valign="top" align="left">Convergent validity</td>
<td valign="top" align="left">Internal consistency</td>
<td valign="top" align="left">Few min. to complete</td>
</tr>
<tr>
<td valign="top" align="left">Personal Inventory</td>
<td valign="top" align="left">NR</td>
<td valign="top" align="left">Q</td>
<td valign="top" align="left">Paper and pencil</td>
<td valign="top" align="left">Patient</td>
<td valign="top" align="left">Newly registered patients</td>
<td valign="top" align="left">Yes</td>
<td valign="top" align="left">Yes</td>
<td valign="top" align="left">NR</td>
</tr>
<tr>
<td valign="top" align="left">Short Form Health Survey (SF-12)<xref ref-type="table-fn" rid="t3fns1">&#x002A;</xref></td>
<td valign="top" align="left">NR</td>
<td valign="top" align="left">Q</td>
<td valign="top" align="left">Web-based, paper and pencil</td>
<td valign="top" align="left">Citizen/Patient</td>
<td valign="top" align="left">Initial health check/outcome assessment in RCT</td>
<td valign="top" align="left">Yes</td>
<td valign="top" align="left">NR</td>
<td valign="top" align="left">NR</td>
</tr>
<tr>
<td valign="top" align="left">Short Form-36 (SF-36)<xref ref-type="table-fn" rid="t3fns1">&#x002A;</xref></td>
<td valign="top" align="left">NR/prior to consultation</td>
<td valign="top" align="left">Q</td>
<td valign="top" align="left">Paper and pencil</td>
<td valign="top" align="left">Patient</td>
<td valign="top" align="left">NR/Outcome assessment</td>
<td valign="top" align="left">Yes</td>
<td valign="top" align="left">NR/Yes</td>
<td valign="top" align="left">NR</td>
</tr>
<tr>
<td valign="top" align="left" colspan="9" style="background-color: #dcdcdc;"><bold>Thematic pattern II: One or more social problem(s)</bold></td>
</tr>
<tr>
<td valign="top" align="left">Composite Abuse Scale (CAS)<xref ref-type="table-fn" rid="t3fns1">&#x002A;</xref></td>
<td valign="top" align="left">NR</td>
<td valign="top" align="left">Q</td>
<td valign="top" align="left">Paper and pencil</td>
<td valign="top" align="left">Patient</td>
<td valign="top" align="left">Screening for study recruitment/Outcome assessment</td>
<td valign="top" align="left">Yes</td>
<td valign="top" align="left">NR</td>
<td valign="top" align="left">NR</td>
</tr>
<tr>
<td valign="top" align="left">Family APGAR<xref ref-type="table-fn" rid="t3fns1">&#x002A;</xref></td>
<td valign="top" align="left">Prior to consultation</td>
<td valign="top" align="left">Q</td>
<td valign="top" align="left">Paper and pencil</td>
<td valign="top" align="left">Patient</td>
<td valign="top" align="left">Newly registered patients</td>
<td valign="top" align="left">Yes</td>
<td valign="top" align="left">NR/Yes</td>
<td valign="top" align="left">NR</td>
</tr>
<tr>
<td valign="top" align="left">Family Strain Questionnaire Short Form (FSQ-SF)<xref ref-type="table-fn" rid="t3fns1">&#x002A;</xref></td>
<td valign="top" align="left">In the waiting room or during consultation</td>
<td valign="top" align="left">Q, I</td>
<td valign="top" align="left">Paper and pencil</td>
<td valign="top" align="left">Patient, physician, other</td>
<td valign="top" align="left">NR</td>
<td valign="top" align="left">Convergent, discriminant validity</td>
<td valign="top" align="left">Internal consistency</td>
<td valign="top" align="left">5 min. to complete</td>
</tr>
<tr>
<td valign="top" align="left">Hopkins-Symptom Checklist (HSCL-25)</td>
<td valign="top" align="left">NR</td>
<td valign="top" align="left">Q</td>
<td valign="top" align="left">Paper and pencil</td>
<td valign="top" align="left">Patient</td>
<td valign="top" align="left">NR</td>
<td valign="top" align="left">Yes</td>
<td valign="top" align="left">NR</td>
<td valign="top" align="left">NR</td>
</tr>
<tr>
<td valign="top" align="left">Patient Health Survey</td>
<td valign="top" align="left">NR</td>
<td valign="top" align="left">Q</td>
<td valign="top" align="left">Paper and pencil</td>
<td valign="top" align="left">Patient (Women)</td>
<td valign="top" align="left">NR</td>
<td valign="top" align="left">Face, criterion validity</td>
<td valign="top" align="left">Yes</td>
<td valign="top" align="left">NR</td>
</tr>
<tr>
<td valign="top" align="left">Social Needs Checklist (SNC)</td>
<td valign="top" align="left">NR</td>
<td valign="top" align="left">Q</td>
<td valign="top" align="left">Paper and pencil</td>
<td valign="top" align="left">Social work students</td>
<td valign="top" align="left">NR</td>
<td valign="top" align="left">Face validity</td>
<td valign="top" align="left">Internal and test-retest reliability</td>
<td valign="top" align="left">NR</td>
</tr>
<tr>
<td valign="top" align="left">Social Problem Questionnaire (SPQ)</td>
<td valign="top" align="left">NR</td>
<td valign="top" align="left">Q</td>
<td valign="top" align="left">Paper and pencil</td>
<td valign="top" align="left">Patient, nurse/Patient</td>
<td valign="top" align="left">Newly registered, unfamiliar, or reticent patients/NR</td>
<td valign="top" align="left">Yes</td>
<td valign="top" align="left">NR</td>
<td valign="top" align="left">5&#x2013;15 min. to complete</td>
</tr>
<tr>
<td valign="top" align="left" colspan="9" style="background-color: #dcdcdc;"><bold>Thematic pattern III: Psychological aspects</bold></td>
</tr>
<tr>
<td valign="top" align="left">Four-Dimensional Symptom Questionnaire (4DSQ)<xref ref-type="table-fn" rid="t3fns1">&#x002A;</xref></td>
<td valign="top" align="left">NR</td>
<td valign="top" align="left">Q</td>
<td valign="top" align="left">Paper and pencil</td>
<td valign="top" align="left">Patient</td>
<td valign="top" align="left">NR</td>
<td valign="top" align="left">Convergent, construct validity</td>
<td valign="top" align="left">Yes</td>
<td valign="top" align="left">NR</td>
</tr>
<tr>
<td valign="top" align="left">General Health Questionnaire (GHQ-12)<xref ref-type="table-fn" rid="t3fns1">&#x002A;</xref></td>
<td valign="top" align="left">NR</td>
<td valign="top" align="left">Q, I</td>
<td valign="top" align="left">Paper and pencil</td>
<td valign="top" align="left">Patient/Patient, physician, other</td>
<td valign="top" align="left">Initial examination/Screening for study recruitment/Outcome assessment</td>
<td valign="top" align="left">Yes</td>
<td valign="top" align="left">NR</td>
<td valign="top" align="left">NR/Yes</td>
</tr>
<tr>
<td valign="top" align="left">General Health Questionnaire (GHQ-28)<xref ref-type="table-fn" rid="t3fns1">&#x002A;</xref></td>
<td valign="top" align="left">Prior to consultation/NR</td>
<td valign="top" align="left">Q</td>
<td valign="top" align="left">Paper and pencil</td>
<td valign="top" align="left">Patient/Patient, physician</td>
<td valign="top" align="left">NR</td>
<td valign="top" align="left">Yes</td>
<td valign="top" align="left">NR</td>
<td valign="top" align="left">NR</td>
</tr>
<tr>
<td valign="top" align="left">General Health Questionnaire (GHQ-30)</td>
<td valign="top" align="left">Prior to consultation/NR</td>
<td valign="top" align="left">Q</td>
<td valign="top" align="left">Paper and pencil</td>
<td valign="top" align="left">Patient/Patient, physician</td>
<td valign="top" align="left">NR/Outcome assessment</td>
<td valign="top" align="left">Yes</td>
<td valign="top" align="left">NR</td>
<td valign="top" align="left">Few min. to complete</td>
</tr>
<tr>
<td valign="top" align="left">General Health Questionnaire (GHQ-60)</td>
<td valign="top" align="left">Prior to consultation</td>
<td valign="top" align="left">Q</td>
<td valign="top" align="left">Paper and pencil</td>
<td valign="top" align="left">Patient</td>
<td valign="top" align="left">NR</td>
<td valign="top" align="left">Yes</td>
<td valign="top" align="left">NR</td>
<td valign="top" align="left">NR</td>
</tr>
<tr>
<td valign="top" align="left">Strengths and Difficulties Questionnaire (SDQ)<xref ref-type="table-fn" rid="t3fns1">&#x002A;</xref></td>
<td valign="top" align="left">NR</td>
<td valign="top" align="left">Q</td>
<td valign="top" align="left">Paper and pencil</td>
<td valign="top" align="left">Patient</td>
<td valign="top" align="left">NR</td>
<td valign="top" align="left">Yes</td>
<td valign="top" align="left">Yes</td>
<td valign="top" align="left">NR</td>
</tr>
</tbody>
</table>
<table-wrap-foot>
<fn id="t3fns1"><p>Q, Questionnaire; I, Interview; M, Mnemonic; NR, Not reported; &#x002A;Freely available.</p></fn>
</table-wrap-foot>
</table-wrap>
<p>The instruments used mostly targeted adults (21), among which two targeted elderly people. One instrument targeted adolescents. For all but one instrument, which contained information reported by the physician, participants themselves were the informants. Few instruments included additional information reported by health professionals (7).</p>
<p>The instruments found were deployed in different formats, mostly as questionnaires (19). Two instruments were used in mixed formats; e.g., as a questionnaire combined with an interview. One instrument was described as a classification system and conceptual framework. The instruments were mostly completed with paper and pencil (19) but also on a tablet or computer (2). For one instrument, the method was not reported.</p>
<p>Information on quality criteria, such as validity, reliability, feasibility, and/or other aspects assessed in relation to the use of the tool were reported differently. When reported, validity was reported in different ways, including internal validity, face, criterion, construct, and external validity. Among these, a validity test was conducted in the study we included for two instruments. For 14 instruments, no detailed information was reported.</p>
<p>Reliability was stated for 10 instruments, of which only four had more detailed information described. Reliability referred to internal consistency, stability, and test-retest reliability. For nine instruments, no information on reliability was provided. For three instruments, different information was available depending on the study description: &#x201C;yes&#x201D; and &#x201C;not reported&#x201D;.</p>
<p>Feasibility was also reported in different ways, generally not systematically. For the majority of instruments (18), no information was provided. For two instruments, it was stated that feasibility was given, but neither had further details provided. For two instruments, different information was available depending on the study: &#x201C;yes&#x201D; and &#x201C;not reported.&#x201D;</p>
<p>Other aspects were mentioned for the evaluation of the instruments, such as acceptance, accuracy, applicability, comprehensibility, effectiveness, efficiency, and usefulness, but the information provided was neither detailed nor structured. For two instruments, no information was provided at all. Our research revealed that 12 of the 22 instruments are currently freely available, while 10 are not.</p>
<p>For most instruments (13), no information was provided on the screening setting (e.g., at home, in the waiting room). When reported, the instruments were mostly completed in the waiting room before, during, or after the medical consultation (9). Instruments were completed within five to ten or fifteen minutes (6), but for most instruments, completion time was not reported (16).</p>
<p>For most instruments (13), no information was provided on the regularity of screening. When reported, instruments were used with newly registered and/or unknown patients (4). In three cases, the tool was used to recruit participants for the study and/or to assess outcomes. Two instruments were used for both purposes.</p>
<p><xref ref-type="table" rid="T2">Table 2</xref> provides information on the focus of each instrument. In general, various aspects around PSPs are covered, varying to some extent depending on the study&#x2019;s objective, target population, and setting. We found considerable heterogeneity in the theoretical conceptualisation, definition, and measurement of PSPs, ranging from psychiatric case findings to specific social problems. To ensure accuracy, we reported the focus of the identified instruments individually.</p>
<p>Finally, because we sought to offer insights into the instruments&#x2019; reported focus, it is worth mentioning three thematic patterns to which the instruments can be assigned. The majority of instruments (9) have a comprehensive focus that includes medical, psychological and/or psychosocial, and/or social aspects (e.g., geriatric assessment). In addition, we found seven instruments measuring one or more social problems (e.g., related to family, partner violence, finances). When specific social problems were addressed, they were related to intimate partner violence (IPV) in female participants (2). Finally, we also found instruments (6) measuring psychological aspects (e.g., stress, anxiety, depression) to identify probable &#x201C;cases.&#x201D;</p>
<p>Not all studies included a conclusion or a conclusion relevant to our research question. Furthermore, there were often no specific conclusions on individual instruments, as these were mostly described in the context of the general study content and objectives as well as other instruments. Where indicated, conclusions related to validity, appropriate classification, identification/detection rates, benefits and improvement in case finding, feasibility, administration, awareness, acceptability, usefulness, a starting point for further discussion and/or subsequent interventions, implementation in daily practice, and also limitations.</p>
<p>In most cases, the authors used a narrative approach to draw conclusions about the instruments studied. These contained statements such as &#x201C;insight [provided by the questionnaire] made it easier for GPs to offer patient-centred counselling and ask questions that offer a holistic picture&#x201D; (SF-12) (<xref ref-type="bibr" rid="B65">65</xref>), &#x201C;acceptable addition to the consultation to facilitate emotionally distressed patients&#x201D; (GHQ-30) (<xref ref-type="bibr" rid="B66">66</xref>), &#x201C;helpful and effective to get an overview of the problem&#x201D; (CAS) (<xref ref-type="bibr" rid="B67">67</xref>), and &#x201C;simple, efficient, and well-suited to the resource- and time-strapped primary care environment&#x201D; (CHAT) (<xref ref-type="bibr" rid="B68">68</xref>). The benefits of the tools for patients were seen to be stimulating conversations, drawing attention to patients, and giving them the opportunity to voice their concerns. The benefits for physicians were seen to be improving recognition skills, initiating conversations, modelling/structuring the conversation, and gaining new information, especially with new and/or reluctant patients. Concerns/limitations were expressed that PSPs-recognition does not necessarily lead to subsequent intervention.</p>
</sec>
</sec>
<sec id="S4" sec-type="discussion">
<title>4. Discussion</title>
<p>Our research yielded 66 articles that met our inclusion criteria and revealed 61 instruments that were developed or used in general practice research in the general population over a five-decade period. In this paper, we presented 22 instruments that were reported as validated.</p>
<p>We identified a wide range of instruments, including validated instruments (e.g., General Health Questionnaire, GHQ; Short Form Health Survey, SF-12), mnemonics (e.g., HEEADSSS [Home environment, Education and employment, Eating, peer-related Activities, Drugs, Sexuality, Suicide/depression, Safety from injury and violence] and SHADESS [Strengths, school, Home, Activities, Drugs, Emotions/eating, Sexuality, Safety]), and instruments specifically designed for trial recruitment. Although we only present the validated instruments in this article, our findings show that non-validated instruments account for almost two thirds of all identified instruments. This could be understood to mean that non-validated instruments are considered as useful as validated instruments.</p>
<p>Notably, overall we found a relatively high number of instruments compared to the number of publications, which is understandable due to the broad use of terms related to PSPs, which varied both between and within publications. Our results show that the large number of instruments found cover a broad area, with most having a comprehensive focus that includes medical, psychological, and/or psychosocial, and/or social aspects. We found social and psychosocial aspects included in several instruments, albeit conceived and reported very differently.</p>
<p>In the research literature, we also found that the consideration of social contexts and problems is described using different terms; for example, psychosocial and social problems, health-related social needs or risks, or social determinants of health. The same applies to the content and focus of the instruments. While we focused our search and study selection on problems and risks, there is also essential work that assesses underlying structural aspects that lead to problems. For example, Bourgois and colleagues present a structural vulnerability assessment tool to help physicians go beyond risk behaviours to consider the negative health consequences of poverty, inequality, and discrimination, and identify patients who may benefit from additional health and social services (<xref ref-type="bibr" rid="B69">69</xref>).</p>
<p>The influence of social circumstances on health is known and recognised, as is the importance of holistic care concepts that take social factors and needs into account (<xref ref-type="bibr" rid="B70">70</xref>, <xref ref-type="bibr" rid="B71">71</xref>). Practical implementation by using tools to identify problems and needs has also gained attention in recent years (<xref ref-type="bibr" rid="B72">72</xref>, <xref ref-type="bibr" rid="B73">73</xref>). In light of the COVID-19 pandemic, the complex interplay between health, social circumstances, and PSPs has become even more apparent, and concerns are being raised about the psychosocial consequences and long-term negative effects of the pandemic that clinical practice must be prepared to address in order to provide appropriate care and support (<xref ref-type="bibr" rid="B74">74</xref>&#x2013;<xref ref-type="bibr" rid="B76">76</xref>).</p>
<p>Similarly, the studies included in our review show the importance of using tools to raise awareness and provide a basis for discussions about PSPs and the associated health risks. In fact, Webb et al., for example, found that a key benefit of using a tool for young people was that it increased confidence in discussing sensitive issues with their GP (<xref ref-type="bibr" rid="B77">77</xref>). In Blom et al.&#x2019;s study, GPs reported that the tools provided them with additional new information and made them more aware of the functions and needs of older people. However, they reported finding it cumbersome to organise multidisciplinary consultations (<xref ref-type="bibr" rid="B78">78</xref>). According to Freund and Lous, the use of the questionnaire (SF-12) can provide insight into the relationship between social life, health, lifestyle, and one&#x2019;s response to stressors and resources. This insight makes it easier for GPs to provide patient-centered counseling and ask questions that provide a holistic picture of the participant (<xref ref-type="bibr" rid="B65">65</xref>). Geyti et al. addressed another aspect in their study, noting that the identification of PSPs does not necessarily lead to the initiation of treatment, where they see a need for further research (<xref ref-type="bibr" rid="B79">79</xref>).</p>
<p>Recent studies show that the responsibility for the subsequent resolution of PSPs does not have to lie solely with GPs. Studies from Germany show that GPs both feel responsible for dealing with social problems and are able to manage them themselves. However, the need for external support was also expressed, as was the view that interprofessional cooperation is helpful and necessary (<xref ref-type="bibr" rid="B3">3</xref>, <xref ref-type="bibr" rid="B80">80</xref>&#x2013;<xref ref-type="bibr" rid="B82">82</xref>). Collaboration between social work and primary care, for example, is considered beneficial and studies show that subjective health, functioning, and self-management can be improved and psychosocial morbidity and barriers to treatment and health maintenance reduced (<xref ref-type="bibr" rid="B83">83</xref>, <xref ref-type="bibr" rid="B84">84</xref>). Therefore, identifying patients with PSPs is a crucial step to ensure that patients receive appropriate care in a timely manner, according to their needs and preferences.</p>
<p>The quality criteria and other aspects described for the evaluation of the instruments identified were different, which makes a comparison difficult and does not allow us to formulate a statement on which instrument(s) can be recommended for use in practice. At the same time, the structural and contextual heterogeneity of the instruments makes prioritisation according to purely diagnostic quality criteria impossible. In the absence of this kind of evidence, an approach that combines available data with the experience and insights of clinical experts from multidisciplinary backgrounds is valuable because it provides guidance where none otherwise exists. Consensus procedures, such as the RAND Corporation/University of California Los Angeles (RAND/UCLA) Appropriateness Method can be helpful in this regard, as they can be used to define appropriate indications and develop criteria for use, care, and management (<xref ref-type="bibr" rid="B85">85</xref>).</p>
<p>From our findings and discussion points, we derive the potential for subsequent research and the link to practice. For example, investigations could be undertaken into whether and which instruments are actually used by general practice professionals in daily practice or why not. Since we did not examine the quality criteria and other criteria used to evaluate the instruments in more detail, as this would have been beyond the scope of our work, future studies could address this aspect by carrying out methodological studies to examine validity, reliability, and feasibility in more depth. If this work is continued, we believe that mixed methods should be used; these are considered particularly important in complex fields such as health and social sciences, as they allow researchers to gain a deeper understanding and answer research questions that cannot be answered by quantitative or qualitative methods alone, thus addressing the complexity of real-life challenges (<xref ref-type="bibr" rid="B86">86</xref>). In order for the step from research to practice to succeed, a consensus procedure like the one just described would be an important contribution to develop a selection of instruments that could or should be used in practice from the perspective of practising healthcare professionals. The development of a corresponding guideline would also be worth considering.</p>
<p>When trying to synthesise such a complex topic there are certain limitations and potential biases. First, we did not assess the quality of the included articles, as this is not the aim of a scoping review. Referring to the WHO and ICPC-2 definition/framework in our understanding of PSPs may have led us to exclude articles that other definitions would have encompassed. Because our results refer to information extracted from the included articles, where information on validation was not always provided, instruments may have been excluded even though validation might have been available. Since we did not set time limits, we included articles from 1978 to the present. Both the way research is conducted and reported and the way PSPs are addressed have changed over that time, limiting the summary and comparability of studies. We note that our findings are predominantly based on literature from high-income countries. PSPs vary in areas with different social and cultural norms and belief contexts, so the results cannot simply be extrapolated to other countries or communities on other continents.</p>
<p>We believe these limitations, however, are offset by numerous strengths. A clear strength of this scoping review is the integration of a wide variety of studies using tailored search strings providing a comprehensive summary of the field. Additionally, strengths include the use of rigorous scoping review methods and compliance with standards for conducting and reporting reviews. All articles were reviewed and extracted by two independent authors to reduce the risk of selection bias. Regular meetings and discussions within our multidisciplinary team, consisting of a sociologist, psychologist, GP, and a mathematician ensured the integration of interdisciplinary perspectives. We have included all types of study designs, reflecting the fact that RCTs are not always appropriate for reporting on a complex topic, which PSPs undoubtedly are.</p>
<p>The integration of psychosocial and social aspects into clinical practice is receiving increasing attention in medicine. The use of identification instruments could be helpful in daily practice to identify patients with PSPs who may benefit from greater support in one or more areas, thus promoting whole-person care for the entire population. This review identified 66 articles reporting on 22 validated instruments that have been studied and used in general practice research. Although the diversity of terms and instruments makes compiling, discussing, and summarising the literature a challenge, the diversity of instruments also demonstrates the great potential and the many ways and variations in which instruments can be used in clinical practice to achieve a deeper understanding and more appropriate care. Adapted and tailored to local circumstances, practice populations, and needs, they could be useful in daily GP practice; however, this requires further research. Given the heterogeneity of studies and instruments, future research efforts should include both a more structured evaluation of instruments and the incorporation of consensus methods to move forward from instrument research to actual use of instruments in daily practice.</p>
</sec>
<sec id="S5" sec-type="author-contributions">
<title>Author contributions</title>
<p>RS, SU, and TF conceptualised and designed the study. TD made contributions. RS and SU developed the search strategy. RS conducted the literature search, developed the data extraction template, performed data analysis and synthesis, wrote the original draft, and reviewed and edited the manuscript. RS and TD independently performed title and abstract screening and full-text review, independently performed a pilot data extraction on a random sample, and subsequently refined the form. RS and a study assistant conducted data extraction independently and met frequently with TD to discuss the process and refine the data extraction form. TD, SU, and TF critically read and commented on the original draft. All authors read and approved the final manuscript, which was completed in December 2022.</p>
</sec>
</body>
<back>
<ack>
<p>We thank our study assistant Pauline Eisenschmidt for her assistance with data cleaning and processing as well as research activities.</p>
</ack>
<sec id="S6" sec-type="COI-statement">
<title>Conflict of interest</title>
<p>The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.</p>
</sec>
<sec id="S7" sec-type="disclaimer">
<title>Publisher&#x2019;s note</title>
<p>All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.</p>
</sec>
<sec id="S8" sec-type="supplementary-material">
<title>Supplementary material</title>
<p>The Supplementary Material for this article can be found online at: <ext-link ext-link-type="uri" xlink:href="https://www.frontiersin.org/articles/10.3389/fmed.2022.1010001/full#supplementary-material">https://www.frontiersin.org/articles/10.3389/fmed.2022.1010001/full#supplementary-material</ext-link></p>
<supplementary-material xlink:href="Table_1.docx" id="TS1" mimetype="application/vnd.openxmlformats-officedocument.wordprocessingml.document" xmlns:xlink="http://www.w3.org/1999/xlink"/>
<supplementary-material xlink:href="Table_2.pdf" id="TS2" mimetype="application/pdf" xmlns:xlink="http://www.w3.org/1999/xlink"/>
<supplementary-material xlink:href="Table_3.docx" id="TS3" mimetype="application/vnd.openxmlformats-officedocument.wordprocessingml.document" xmlns:xlink="http://www.w3.org/1999/xlink"/>
<supplementary-material xlink:href="Table_4.pdf" id="TS4" mimetype="application/pdf" xmlns:xlink="http://www.w3.org/1999/xlink"/>
<supplementary-material xlink:href="Table_5.docx" id="TS5" mimetype="application/vnd.openxmlformats-officedocument.wordprocessingml.document" xmlns:xlink="http://www.w3.org/1999/xlink"/>
</sec>
<ref-list>
<title>References</title>
<ref id="B1"><label>1.</label><citation citation-type="journal"><collab>DEGAM.</collab> <source><italic>DEGAM-Zukunftspositionen.</italic></source> (<year>2013</year>). <comment>Available online at</comment>: <ext-link ext-link-type="uri" xlink:href="https://www.degam.de/files/Inhalte/Degam-Inhalte/Ueber_uns/Positionspapiere/DEGAM_Zukunftspositionen.pdf">https://www.degam.de/files/Inhalte/Degam-Inhalte/Ueber_uns/Positionspapiere/DEGAM_Zukunftspositionen.pdf</ext-link> <comment>(accessed July 6, 2021)</comment>.</citation></ref>
<ref id="B2"><label>2.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Hartmann</surname> <given-names>M</given-names></name> <name><surname>Finkenzeller</surname> <given-names>C</given-names></name> <name><surname>Boehlen</surname> <given-names>F</given-names></name> <name><surname>Wagenlechner</surname> <given-names>P</given-names></name> <name><surname>Peters-Klimm</surname> <given-names>F</given-names></name> <name><surname>Herzog</surname> <given-names>W</given-names></name></person-group>. <article-title>Psychosomatische Sprechstunde in der Hausarztpraxis &#x2013; ein neues Kooperationsmodell von Psychosomatik und Allgemeinmedizin.</article-title> <source><italic>Balint J.</italic></source> (<year>2018</year>) <volume>19</volume>:<fpage>116</fpage>&#x2013;<lpage>20</lpage>. <pub-id pub-id-type="doi">10.1055/a-0795-2048</pub-id></citation></ref>
<ref id="B3"><label>3.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Zimmermann</surname> <given-names>T</given-names></name> <name><surname>Mews</surname> <given-names>C</given-names></name> <name><surname>Kloppe</surname> <given-names>T</given-names></name> <name><surname>Tetzlaff</surname> <given-names>B</given-names></name> <name><surname>Hadwiger</surname> <given-names>M</given-names></name> <name><surname>von dem Knesebeck</surname> <given-names>O</given-names></name><etal/></person-group> <article-title>Soziale Probleme in der haus&#x00E4;rztlichen Versorgung &#x2013; H&#x00E4;ufigkeit, Reaktionen, Handlungsoptionen und erw&#x00FC;nschter Unterst&#x00FC;tzungsbedarf aus der Sicht von Haus&#x00E4;rztinnen und Haus&#x00E4;rzten. [Social problems in primary health care: prevalence, responses, course of action, and the need for support from a general practitioners&#x2019; point of view].</article-title> <source><italic>Z Evid Fortbild Qual Gesundhwes.</italic></source> (<year>2018</year>) <volume>131&#x2013;32</volume>:<fpage>81</fpage>&#x2013;<lpage>9</lpage>. <pub-id pub-id-type="doi">10.1016/j.zefq.2018.01.008</pub-id> <pub-id pub-id-type="pmid">29510956</pub-id></citation></ref>
<ref id="B4"><label>4.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Santo</surname> <given-names>E</given-names></name> <name><surname>Vo</surname> <given-names>M</given-names></name> <name><surname>Uratsu</surname> <given-names>C</given-names></name> <name><surname>Grant</surname> <given-names>R</given-names></name></person-group>. <article-title>Patient-defined visit priorities in primary care: psychosocial versus medically-related concerns.</article-title> <source><italic>J Am Board Fam Med.</italic></source> (<year>2019</year>) <volume>32</volume>:<fpage>513</fpage>&#x2013;<lpage>20</lpage>. <pub-id pub-id-type="doi">10.3122/jabfm.2019.04.180380</pub-id> <pub-id pub-id-type="pmid">31300571</pub-id></citation></ref>
<ref id="B5"><label>5.</label><citation citation-type="journal"><collab>World Health Organization [WHO].</collab> <source><italic>Social determinants of health.</italic></source> (<year>2019</year>). <comment>Available online at</comment>: <ext-link ext-link-type="uri" xlink:href="https://www.who.int/health-topics/social-determinants-of-health">https://www.who.int/health-topics/social-determinants-of-health</ext-link> <comment>(accessed March 4, 2022)</comment>.</citation></ref>
<ref id="B6"><label>6.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Kivim&#x00E4;ki</surname> <given-names>M</given-names></name> <name><surname>Batty</surname> <given-names>G</given-names></name> <name><surname>Pentti</surname> <given-names>J</given-names></name> <name><surname>Shipley</surname> <given-names>M</given-names></name> <name><surname>Sipil&#x00E4;</surname> <given-names>P</given-names></name> <name><surname>Nyberg</surname> <given-names>S</given-names></name><etal/></person-group> <article-title>Association between socioeconomic status and the development of mental and physical health conditions in adulthood: a multi-cohort study.</article-title> <source><italic>Lancet Public Health.</italic></source> (<year>2020</year>) <volume>5</volume>:<fpage>e140</fpage>&#x2013;<lpage>9</lpage>. <pub-id pub-id-type="doi">10.1016/S2468-2667(19)30248-8</pub-id></citation></ref>
<ref id="B7"><label>7.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Brunner</surname> <given-names>E</given-names></name></person-group>. <article-title>Social factors and cardiovascular morbidity.</article-title> <source><italic>Neurosci Biobehav Rev.</italic></source> (<year>2017</year>) <volume>74</volume>:<fpage>260</fpage>&#x2013;<lpage>8</lpage>. <pub-id pub-id-type="doi">10.1016/j.neubiorev.2016.05.004</pub-id> <pub-id pub-id-type="pmid">27177828</pub-id></citation></ref>
<ref id="B8"><label>8.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Marmot</surname> <given-names>M.</given-names></name></person-group> <source><italic>Review of social determinants and the health divide in the WHO European region: final report.</italic></source> <publisher-loc>Copenhagen</publisher-loc>: <publisher-name>World Health Organization</publisher-name> (<year>2014</year>). p. <fpage>188</fpage>.</citation></ref>
<ref id="B9"><label>9.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Marmot</surname> <given-names>M</given-names></name> <name><surname>Friel</surname> <given-names>S</given-names></name> <name><surname>Bell</surname> <given-names>R</given-names></name> <name><surname>Houweling</surname> <given-names>T</given-names></name> <name><surname>Taylor</surname> <given-names>S</given-names></name></person-group>. <article-title>Commission on social determinants of health. Closing the gap in a generation: health equity through action on the social determinants of health.</article-title> <source><italic>Lancet.</italic></source> (<year>2008</year>) <volume>372</volume>:<fpage>1661</fpage>&#x2013;<lpage>9</lpage>. <pub-id pub-id-type="doi">10.1016/S0140-6736(08)61690-6</pub-id></citation></ref>
<ref id="B10"><label>10.</label><citation citation-type="journal"><collab>Institute of Medicine, Board on Neuroscience and Behavioral Health, Committee on Health and Behavior: Research, Practice and Policy.</collab> <source><italic>Health and behavior: the interplay of biological, behavioral, and societal influences.</italic></source> <publisher-loc>Washington, DC</publisher-loc>: <publisher-name>National Academies Press</publisher-name> (<year>2001</year>). p. <fpage>395</fpage>.</citation></ref>
<ref id="B11"><label>11.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Hakulinen</surname> <given-names>C</given-names></name> <name><surname>Pulkki-R&#x00E5;back</surname> <given-names>L</given-names></name> <name><surname>Virtanen</surname> <given-names>M</given-names></name> <name><surname>Jokela</surname> <given-names>M</given-names></name> <name><surname>Kivim&#x00E4;ki</surname> <given-names>M</given-names></name> <name><surname>Elovainio</surname> <given-names>M</given-names></name></person-group>. <article-title>Social isolation and loneliness as risk factors for myocardial infarction, stroke and mortality: UK Biobank cohort study of 479 054 men and women.</article-title> <source><italic>Heart.</italic></source> (<year>2018</year>) <volume>104</volume>:<fpage>1536</fpage>&#x2013;<lpage>42</lpage>. <pub-id pub-id-type="doi">10.1136/heartjnl-2017-312663</pub-id> <pub-id pub-id-type="pmid">29588329</pub-id></citation></ref>
<ref id="B12"><label>12.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Kivim&#x00E4;ki</surname> <given-names>M</given-names></name> <name><surname>Steptoe</surname> <given-names>A</given-names></name></person-group>. <article-title>Effects of stress on the development and progression of cardiovascular disease.</article-title> <source><italic>Nat Rev Cardiol.</italic></source> (<year>2018</year>) <volume>15</volume>:<fpage>215</fpage>&#x2013;<lpage>29</lpage>. <pub-id pub-id-type="doi">10.1038/nrcardio.2017.189</pub-id> <pub-id pub-id-type="pmid">29213140</pub-id></citation></ref>
<ref id="B13"><label>13.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Everson-Rose</surname> <given-names>S</given-names></name> <name><surname>Lewis</surname> <given-names>T</given-names></name></person-group>. <article-title>Psychosocial factors and cardiovascular diseases.</article-title> <source><italic>Annu Rev Public Health.</italic></source> (<year>2005</year>) <volume>26</volume>:<fpage>469</fpage>&#x2013;<lpage>500</lpage>. <pub-id pub-id-type="doi">10.1146/annurev.publhealth.26.021304.144542</pub-id> <pub-id pub-id-type="pmid">15760298</pub-id></citation></ref>
<ref id="B14"><label>14.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Hackett</surname> <given-names>R</given-names></name> <name><surname>Steptoe</surname> <given-names>A</given-names></name></person-group>. <article-title>Psychosocial factors in diabetes and cardiovascular risk.</article-title> <source><italic>Curr Cardiol Rep.</italic></source> (<year>2016</year>) <volume>18</volume>:<issue>95</issue>. <pub-id pub-id-type="doi">10.1007/s11886-016-0771-4</pub-id> <pub-id pub-id-type="pmid">27566328</pub-id></citation></ref>
<ref id="B15"><label>15.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Hamer</surname> <given-names>M</given-names></name> <name><surname>Kivimaki</surname> <given-names>M</given-names></name> <name><surname>Stamatakis</surname> <given-names>E</given-names></name> <name><surname>Batty</surname> <given-names>G</given-names></name></person-group>. <article-title>Psychological distress and infectious disease mortality in the general population.</article-title> <source><italic>Brain Behav Immun.</italic></source> (<year>2019</year>) <volume>76</volume>:<fpage>280</fpage>&#x2013;<lpage>3</lpage>. <pub-id pub-id-type="doi">10.1016/j.bbi.2018.12.011</pub-id> <pub-id pub-id-type="pmid">30579940</pub-id></citation></ref>
<ref id="B16"><label>16.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Cohen</surname> <given-names>S</given-names></name> <name><surname>Tyrrell</surname> <given-names>D</given-names></name> <name><surname>Smith</surname> <given-names>A</given-names></name></person-group>. <article-title>Psychological stress and susceptibility to the common cold.</article-title> <source><italic>N Engl J Med.</italic></source> (<year>1991</year>) <volume>325</volume>:<fpage>606</fpage>&#x2013;<lpage>12</lpage>. <pub-id pub-id-type="doi">10.1056/NEJM199108293250903</pub-id> <pub-id pub-id-type="pmid">1713648</pub-id></citation></ref>
<ref id="B17"><label>17.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Cohen</surname> <given-names>S</given-names></name></person-group>. <article-title>Psychosocial vulnerabilities to upper respiratory infectious illness: implications for susceptibility to coronavirus disease 2019 (COVID-19).</article-title> <source><italic>Perspect Psychol Sci.</italic></source> (<year>2021</year>) <volume>16</volume>:<fpage>161</fpage>&#x2013;<lpage>74</lpage>. <pub-id pub-id-type="doi">10.1177/1745691620942516</pub-id> <pub-id pub-id-type="pmid">32640177</pub-id></citation></ref>
<ref id="B18"><label>18.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Segerstrom</surname> <given-names>S</given-names></name> <name><surname>Miller</surname> <given-names>G</given-names></name></person-group>. <article-title>Psychological stress and the human immune system: a meta-analytic study of 30 years of inquiry.</article-title> <source><italic>Psychol Bull.</italic></source> (<year>2004</year>) <volume>130</volume>:<fpage>601</fpage>&#x2013;<lpage>30</lpage>. <pub-id pub-id-type="doi">10.1037/0033-2909.130.4.601</pub-id> <pub-id pub-id-type="pmid">15250815</pub-id></citation></ref>
<ref id="B19"><label>19.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Furman</surname> <given-names>D</given-names></name> <name><surname>Campisi</surname> <given-names>J</given-names></name> <name><surname>Verdin</surname> <given-names>E</given-names></name> <name><surname>Carrera-Bastos</surname> <given-names>P</given-names></name> <name><surname>Targ</surname> <given-names>S</given-names></name> <name><surname>Franceschi</surname> <given-names>C</given-names></name><etal/></person-group> <article-title>Chronic inflammation in the etiology of disease across the life span.</article-title> <source><italic>Nat Med.</italic></source> (<year>2019</year>) <volume>25</volume>:<fpage>1822</fpage>&#x2013;<lpage>32</lpage>. <pub-id pub-id-type="doi">10.1038/s41591-019-0675-0</pub-id> <pub-id pub-id-type="pmid">31806905</pub-id></citation></ref>
<ref id="B20"><label>20.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>H&#x00E4;nsel</surname> <given-names>A</given-names></name> <name><surname>Hong</surname> <given-names>S</given-names></name> <name><surname>C&#x00E1;mara</surname> <given-names>R</given-names></name> <name><surname>von K&#x00E4;nel</surname> <given-names>R</given-names></name></person-group>. <article-title>Inflammation as a psychophysiological biomarker in chronic psychosocial stress.</article-title> <source><italic>Neurosci Biobehav Rev.</italic></source> (<year>2010</year>) <volume>35</volume>:<fpage>115</fpage>&#x2013;<lpage>21</lpage>. <pub-id pub-id-type="doi">10.1016/j.neubiorev.2009.12.012</pub-id> <pub-id pub-id-type="pmid">20026349</pub-id></citation></ref>
<ref id="B21"><label>21.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Krantz</surname> <given-names>D</given-names></name> <name><surname>McCeney</surname> <given-names>M</given-names></name></person-group>. <article-title>Effects of psychological and social factors on organic disease: a critical assessment of research on coronary heart disease.</article-title> <source><italic>Annu Rev Psychol.</italic></source> (<year>2002</year>) <volume>53</volume>:<fpage>341</fpage>&#x2013;<lpage>69</lpage>. <pub-id pub-id-type="doi">10.1146/annurev.psych.53.100901.135208</pub-id> <pub-id pub-id-type="pmid">11752489</pub-id></citation></ref>
<ref id="B22"><label>22.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Kuper</surname> <given-names>H</given-names></name> <name><surname>Marmot</surname> <given-names>M</given-names></name> <name><surname>Hemingway</surname> <given-names>H</given-names></name></person-group>. <article-title>Systematic review of prospective cohort studies of psychosocial factors in the etiology and prognosis of coronary heart disease.</article-title> <source><italic>Semin Vasc Med.</italic></source> (<year>2002</year>) <volume>2</volume>:<fpage>267</fpage>&#x2013;<lpage>314</lpage>. <pub-id pub-id-type="doi">10.1055/s-2002-35401</pub-id> <pub-id pub-id-type="pmid">16222620</pub-id></citation></ref>
<ref id="B23"><label>23.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Hemingway</surname> <given-names>H</given-names></name> <name><surname>Marmot</surname> <given-names>M</given-names></name></person-group>. <article-title>Evidence based cardiology: psychosocial factors in the aetiology and prognosis of coronary heart disease: systematic review of prospective cohort studies.</article-title> <source><italic>BMJ.</italic></source> (<year>1999</year>) <volume>318</volume>:<fpage>1460</fpage>&#x2013;<lpage>7</lpage>. <pub-id pub-id-type="doi">10.1136/bmj.318.7196.1460</pub-id> <pub-id pub-id-type="pmid">10346775</pub-id></citation></ref>
<ref id="B24"><label>24.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Holt-Lunstad</surname> <given-names>J</given-names></name> <name><surname>Smith</surname> <given-names>T</given-names></name> <name><surname>Baker</surname> <given-names>M</given-names></name> <name><surname>Harris</surname> <given-names>T</given-names></name> <name><surname>Stephenson</surname> <given-names>D</given-names></name></person-group>. <article-title>Loneliness and social isolation as risk factors for mortality: a meta-analytic review.</article-title> <source><italic>Perspect Psychol Sci.</italic></source> (<year>2015</year>) <volume>10</volume>:<fpage>227</fpage>&#x2013;<lpage>37</lpage>. <pub-id pub-id-type="doi">10.1177/1745691614568352</pub-id> <pub-id pub-id-type="pmid">25910392</pub-id></citation></ref>
<ref id="B25"><label>25.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Pantell</surname> <given-names>M</given-names></name> <name><surname>Rehkopf</surname> <given-names>D</given-names></name> <name><surname>Jutte</surname> <given-names>D</given-names></name> <name><surname>Syme</surname> <given-names>S</given-names></name> <name><surname>Balmes</surname> <given-names>J</given-names></name> <name><surname>Adler</surname> <given-names>N</given-names></name></person-group>. <article-title>Social isolation: a predictor of mortality comparable to traditional clinical risk factors.</article-title> <source><italic>Am J Public Health.</italic></source> (<year>2013</year>) <volume>103</volume>:<fpage>2056</fpage>&#x2013;<lpage>62</lpage>. <pub-id pub-id-type="doi">10.2105/AJPH.2013.301261</pub-id> <pub-id pub-id-type="pmid">24028260</pub-id></citation></ref>
<ref id="B26"><label>26.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Beller</surname> <given-names>J</given-names></name> <name><surname>Wagner</surname> <given-names>A</given-names></name></person-group>. <article-title>Loneliness, social isolation, their synergistic interaction, and mortality.</article-title> <source><italic>Health Psychol.</italic></source> (<year>2018</year>) <volume>37</volume>:<fpage>808</fpage>&#x2013;<lpage>13</lpage>. <pub-id pub-id-type="doi">10.1037/hea0000605</pub-id> <pub-id pub-id-type="pmid">30138019</pub-id></citation></ref>
<ref id="B27"><label>27.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Holt-Lunstad</surname> <given-names>J</given-names></name></person-group>. <article-title>The potential public health relevance of social isolation and loneliness: prevalence, epidemiology, and risk factors.</article-title> <source><italic>Public Policy Aging Rep.</italic></source> (<year>2018</year>) <volume>27</volume>:<fpage>127</fpage>&#x2013;<lpage>30</lpage>. <pub-id pub-id-type="doi">10.1093/ppar/prx030</pub-id></citation></ref>
<ref id="B28"><label>28.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Amick</surname> <given-names>B</given-names> <suffix>III</suffix></name> <name><surname>McDonough</surname> <given-names>P</given-names></name> <name><surname>Chang</surname> <given-names>H</given-names></name> <name><surname>Rogers</surname> <given-names>W</given-names></name> <name><surname>Pieper</surname> <given-names>C</given-names></name> <name><surname>Duncan</surname> <given-names>G</given-names></name></person-group>. <article-title>Relationship between all-cause mortality and cumulative working life course psychosocial and physical exposures in the United States labor market from 1968 to 1992.</article-title> <source><italic>Psychosom Med.</italic></source> (<year>2002</year>) <volume>64</volume>:<fpage>370</fpage>&#x2013;<lpage>81</lpage>. <pub-id pub-id-type="doi">10.1097/00006842-200205000-00002</pub-id> <pub-id pub-id-type="pmid">12021412</pub-id></citation></ref>
<ref id="B29"><label>29.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Shirom</surname> <given-names>A</given-names></name> <name><surname>Toker</surname> <given-names>S</given-names></name> <name><surname>Alkaly</surname> <given-names>Y</given-names></name> <name><surname>Jacobson</surname> <given-names>O</given-names></name> <name><surname>Balicer</surname> <given-names>R</given-names></name></person-group>. <article-title>Work-based predictors of mortality: a 20-year follow-up of healthy employees.</article-title> <source><italic>Health Psychol.</italic></source> (<year>2011</year>) <volume>30</volume>:<fpage>268</fpage>&#x2013;<lpage>75</lpage>. <pub-id pub-id-type="doi">10.1037/a0023138</pub-id> <pub-id pub-id-type="pmid">21553970</pub-id></citation></ref>
<ref id="B30"><label>30.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Niedhammer</surname> <given-names>I</given-names></name> <name><surname>Milner</surname> <given-names>A</given-names></name> <name><surname>Coutrot</surname> <given-names>T</given-names></name> <name><surname>Geoffroy-Perez</surname> <given-names>B</given-names></name> <name><surname>LaMontagne</surname> <given-names>A</given-names></name> <name><surname>Chastang</surname> <given-names>J</given-names></name></person-group>. <article-title>Psychosocial work factors of the job strain model and all-cause mortality: the STRESSJEM prospective cohort study.</article-title> <source><italic>Psychosom Med.</italic></source> (<year>2021</year>) <volume>83</volume>:<fpage>62</fpage>&#x2013;<lpage>70</lpage>.</citation></ref>
<ref id="B31"><label>31.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Kivim&#x00E4;ki</surname> <given-names>M</given-names></name> <name><surname>Nyberg</surname> <given-names>S</given-names></name> <name><surname>Batty</surname> <given-names>G</given-names></name> <name><surname>Fransson</surname> <given-names>E</given-names></name> <name><surname>Heikkil&#x00E4;</surname> <given-names>K</given-names></name> <name><surname>Alfredsson</surname> <given-names>L</given-names></name><etal/></person-group> <article-title>Job strain as a risk factor for coronary heart disease: a collaborative meta-analysis of individual participant data.</article-title> <source><italic>Lancet.</italic></source> (<year>2012</year>) <volume>380</volume>:<fpage>1491</fpage>&#x2013;<lpage>7</lpage>. <pub-id pub-id-type="doi">10.1016/S0140-6736(12)60994-5</pub-id></citation></ref>
<ref id="B32"><label>32.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Virtanen</surname> <given-names>M</given-names></name> <name><surname>Nyberg</surname> <given-names>S</given-names></name> <name><surname>Batty</surname> <given-names>G</given-names></name> <name><surname>Jokela</surname> <given-names>M</given-names></name> <name><surname>Heikkil&#x00E4;</surname> <given-names>K</given-names></name> <name><surname>Fransson</surname> <given-names>E</given-names></name><etal/></person-group> <article-title>Perceived job insecurity as a risk factor for incident coronary heart disease: systematic review and meta-analysis.</article-title> <source><italic>BMJ.</italic></source> (<year>2013</year>) <volume>347</volume>:<issue>f4746</issue>. <pub-id pub-id-type="doi">10.1136/bmj.f4746</pub-id> <pub-id pub-id-type="pmid">23929894</pub-id></citation></ref>
<ref id="B33"><label>33.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Gulbrandsen</surname> <given-names>P</given-names></name> <name><surname>Fugelli</surname> <given-names>P</given-names></name> <name><surname>Sandvik</surname> <given-names>L</given-names></name> <name><surname>Hjortdahl</surname> <given-names>P</given-names></name></person-group>. <article-title>Influence of social problems on management in general practice: multipractice questionnaire survey.</article-title> <source><italic>BMJ.</italic></source> (<year>1998</year>) <volume>317</volume>:<fpage>28</fpage>&#x2013;<lpage>32</lpage>. <pub-id pub-id-type="doi">10.1136/bmj.317.7150.28</pub-id> <pub-id pub-id-type="pmid">9651266</pub-id></citation></ref>
<ref id="B34"><label>34.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Huibers</surname> <given-names>M</given-names></name> <name><surname>Beurskens</surname> <given-names>A</given-names></name> <name><surname>Bleijenberg</surname> <given-names>G</given-names></name> <name><surname>van Schayck</surname> <given-names>C</given-names></name></person-group>. <article-title>Psychosocial interventions by general practitioners.</article-title> <source><italic>Cochrane Database Syst Rev.</italic></source> (<year>2007</year>) <volume>2007</volume>:<issue>CD003494</issue>. <pub-id pub-id-type="doi">10.1002/14651858.CD003494.pub2</pub-id> <pub-id pub-id-type="pmid">17636726</pub-id></citation></ref>
<ref id="B35"><label>35.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Zantinge</surname> <given-names>E</given-names></name> <name><surname>Verhaak</surname> <given-names>P</given-names></name> <name><surname>Bensing</surname> <given-names>J</given-names></name></person-group>. <article-title>The workload of GPs: patients with psychological and somatic problems compared.</article-title> <source><italic>Fam Pract.</italic></source> (<year>2005</year>) <volume>22</volume>:<fpage>293</fpage>&#x2013;<lpage>7</lpage>. <pub-id pub-id-type="doi">10.1093/fampra/cmh732</pub-id> <pub-id pub-id-type="pmid">15778235</pub-id></citation></ref>
<ref id="B36"><label>36.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Del Piccolo</surname> <given-names>L</given-names></name> <name><surname>Saltini</surname> <given-names>A</given-names></name> <name><surname>Zimmermann</surname> <given-names>C</given-names></name></person-group>. <article-title>Which patients talk about stressful life events and social problems to the general practitioner?</article-title> <source><italic>Psychol Med.</italic></source> (<year>1998</year>) <volume>28</volume>:<fpage>1289</fpage>&#x2013;<lpage>99</lpage>. <pub-id pub-id-type="doi">10.1017/s0033291798007478</pub-id> <pub-id pub-id-type="pmid">9854270</pub-id></citation></ref>
<ref id="B37"><label>37.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Gulbrandsen</surname> <given-names>P</given-names></name> <name><surname>Hjortdahl</surname> <given-names>P</given-names></name> <name><surname>Fugelli</surname> <given-names>P</given-names></name></person-group>. <article-title>General practitioners&#x2019; knowledge of their patients&#x2019; psychosocial problems: multipractice questionnaire survey.</article-title> <source><italic>BMJ.</italic></source> (<year>1997</year>) <volume>314</volume>:<fpage>1014</fpage>&#x2013;<lpage>8</lpage>. <pub-id pub-id-type="doi">10.1136/bmj.314.7086.1014</pub-id> <pub-id pub-id-type="pmid">9112847</pub-id></citation></ref>
<ref id="B38"><label>38.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Fritzsche</surname> <given-names>K</given-names></name> <name><surname>Sandholzer</surname> <given-names>H</given-names></name> <name><surname>Werner</surname> <given-names>J</given-names></name> <name><surname>Brucks</surname> <given-names>U</given-names></name> <name><surname>Cierpka</surname> <given-names>M</given-names></name> <name><surname>Deter</surname> <given-names>H</given-names></name><etal/></person-group> <article-title>Psychotherapeutische und psychosoziale Behandlungsmassnahmen in der Hausarztpraxis. Ergebnisse im Rahmen eines Demonstrationsprojektes zur Qualit&#x00E4;tssicherung in der psychosomatischen Grundversorgung. [Psychotherapeutic and psychosocial therapy in general practice. Results of demonstration project on quality management in psychosocial primary care].</article-title> <source><italic>Psychother Psychosom Med Psychol.</italic></source> (<year>2000</year>) <volume>50</volume>:<fpage>240</fpage>&#x2013;<lpage>6</lpage>. <pub-id pub-id-type="doi">10.1055/s-2000-13252</pub-id> <pub-id pub-id-type="pmid">10909296</pub-id></citation></ref>
<ref id="B39"><label>39.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Grayer</surname> <given-names>J</given-names></name> <name><surname>Cape</surname> <given-names>J</given-names></name> <name><surname>Orpwood</surname> <given-names>L</given-names></name> <name><surname>Leibowitz</surname> <given-names>J</given-names></name> <name><surname>Buszewicz</surname> <given-names>M</given-names></name></person-group>. <article-title>Facilitating access to voluntary and community services for patients with psychosocial problems: a before-after evaluation.</article-title> <source><italic>BMC Fam Pract.</italic></source> (<year>2008</year>) <volume>9</volume>:<issue>27</issue>. <pub-id pub-id-type="doi">10.1186/1471-2296-9-27</pub-id> <pub-id pub-id-type="pmid">18462500</pub-id></citation></ref>
<ref id="B40"><label>40.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Jobst</surname> <given-names>D</given-names></name> <name><surname>Joos</surname> <given-names>S</given-names></name></person-group>. <article-title>Soziale Patientenanliegen&#x2014;eine Erhebung in Hausarztpraxen.</article-title> <source><italic>Z Allg Med.</italic></source> (<year>2014</year>) <volume>90</volume>:<fpage>496</fpage>&#x2013;<lpage>501</lpage>.</citation></ref>
<ref id="B41"><label>41.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Laux</surname> <given-names>G</given-names></name> <name><surname>K&#x00FC;hnlein</surname> <given-names>T</given-names></name> <name><surname>Gutscher</surname> <given-names>A</given-names></name> <name><surname>Szecsenyi</surname> <given-names>J.</given-names></name></person-group> <source><italic>Versorgungsforschung der Hausarztpraxis: Ergebnisse aus dem CONTENT-Projekt 2006&#x2013;2009.</italic></source> <publisher-loc>Munich</publisher-loc>: <publisher-name>Urban und Vogel</publisher-name> (<year>2011</year>). p. <fpage>112</fpage>.</citation></ref>
<ref id="B42"><label>42.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Popay</surname> <given-names>J</given-names></name> <name><surname>Kowarzik</surname> <given-names>U</given-names></name> <name><surname>Mallinson</surname> <given-names>S</given-names></name> <name><surname>Mackian</surname> <given-names>S</given-names></name> <name><surname>Barker</surname> <given-names>J</given-names></name></person-group>. <article-title>Social problems, primary care and pathways to help and support: addressing health inequalities at the individual level. Part I: the GP perspective.</article-title> <source><italic>J Epidemiol Community Health.</italic></source> (<year>2007</year>) <volume>61</volume>:<fpage>966</fpage>&#x2013;<lpage>71</lpage>. <pub-id pub-id-type="doi">10.1136/jech.2007.061937</pub-id> <pub-id pub-id-type="pmid">17933954</pub-id></citation></ref>
<ref id="B43"><label>43.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Van Hook</surname> <given-names>M</given-names></name></person-group>. <article-title>Psychosocial issues within primary health care settings: challenges and opportunities for social work practice.</article-title> <source><italic>Soc Work Health Care.</italic></source> (<year>2003</year>) <volume>38</volume>:<fpage>63</fpage>&#x2013;<lpage>80</lpage>. <pub-id pub-id-type="doi">10.1300/j010v38n01_04</pub-id></citation></ref>
<ref id="B44"><label>44.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Vannieuwenborg</surname> <given-names>L</given-names></name> <name><surname>Buntinx</surname> <given-names>F</given-names></name> <name><surname>De Lepeleire</surname> <given-names>J</given-names></name></person-group>. <article-title>Presenting prevalence and management of psychosocial problems in primary care in Flanders.</article-title> <source><italic>Arch Public Health.</italic></source> (<year>2015</year>) <volume>73</volume>:<issue>10</issue>. <pub-id pub-id-type="doi">10.1186/s13690-015-0061-4</pub-id> <pub-id pub-id-type="pmid">25755877</pub-id></citation></ref>
<ref id="B45"><label>45.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Wilfer</surname> <given-names>T</given-names></name> <name><surname>Braungardt</surname> <given-names>T</given-names></name> <name><surname>Schneider</surname> <given-names>W</given-names></name></person-group>. <article-title>Soziale Probleme in der haus&#x00E4;rztlichen Praxis. [Social problems in primary care].</article-title> <source><italic>Z Psychosom Med Psychother.</italic></source> (<year>2018</year>) <volume>64</volume>:<fpage>250</fpage>&#x2013;<lpage>61</lpage>. <pub-id pub-id-type="doi">10.13109/zptm.2018.64.3.250</pub-id> <pub-id pub-id-type="pmid">30829155</pub-id></citation></ref>
<ref id="B46"><label>46.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Bikson</surname> <given-names>K</given-names></name> <name><surname>McGuire</surname> <given-names>J</given-names></name> <name><surname>Blue-Howells</surname> <given-names>J</given-names></name> <name><surname>Seldin-Sommer</surname> <given-names>L</given-names></name></person-group>. <article-title>Psychosocial problems in primary care: patient and provider perceptions.</article-title> <source><italic>Soc Work Health Care.</italic></source> (<year>2009</year>) <volume>48</volume>:<fpage>736</fpage>&#x2013;<lpage>49</lpage>. <pub-id pub-id-type="doi">10.1080/00981380902929057</pub-id> <pub-id pub-id-type="pmid">20182986</pub-id></citation></ref>
<ref id="B47"><label>47.</label><citation citation-type="journal"><collab>Wonca International Classification.</collab> <source><italic>ICPC-2 English.</italic></source> <comment>Available online at</comment>: <ext-link ext-link-type="uri" xlink:href="https://ehelse.no/kodeverk/icpc-2e&#x2013;english-version/_/attachment/download/56f8d2b7-803c-46dc-84cd-0b4838eba605:b1b6ccf719152365ab9668c45fb5d0aced197038/ICPC-2e-English.pdf">https://ehelse.no/kodeverk/icpc-2e&#x2013;english-version/_/attachment/download/56f8d2b7-803c-46dc-84cd-0b4838eba605:b1b6ccf719152365ab9668c45fb5d0aced197038/ICPC-2e-English.pdf</ext-link> <comment>(accessed July 6, 2021)</comment>.</citation></ref>
<ref id="B48"><label>48.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Rosendal</surname> <given-names>M</given-names></name> <name><surname>Vedsted</surname> <given-names>P</given-names></name> <name><surname>Christensen</surname> <given-names>K</given-names></name> <name><surname>Moth</surname> <given-names>G</given-names></name></person-group>. <article-title>Psychological and social problems in primary care patients - general practitioners&#x2019; assessment and classification.</article-title> <source><italic>Scand J Prim Health Care.</italic></source> (<year>2013</year>) <volume>31</volume>:<fpage>43</fpage>&#x2013;<lpage>9</lpage>. <pub-id pub-id-type="doi">10.3109/02813432.2012.751688</pub-id> <pub-id pub-id-type="pmid">23281962</pub-id></citation></ref>
<ref id="B49"><label>49.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Larisch</surname> <given-names>A</given-names></name> <name><surname>Fisch</surname> <given-names>V</given-names></name> <name><surname>Fritzsche</surname> <given-names>K</given-names></name></person-group>. <article-title>Kosten-Nutzen-Aspekte psychosozialer Interventionen bei somatisierenden Patienten in der Hausarztpraxis.</article-title> <source><italic>Z Klin Psychol Psychother.</italic></source> (<year>2005</year>) <volume>34</volume>:<fpage>282</fpage>&#x2013;<lpage>90</lpage>. <pub-id pub-id-type="doi">10.1026/1616-3443.34.4.282</pub-id></citation></ref>
<ref id="B50"><label>50.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>V&#x00E1;zquez-Barquero</surname> <given-names>J</given-names></name> <name><surname>Garc&#x00ED;a</surname> <given-names>J</given-names></name> <name><surname>Sim&#x00F3;n</surname> <given-names>J</given-names></name> <name><surname>Iglesias</surname> <given-names>C</given-names></name> <name><surname>Montejo</surname> <given-names>J</given-names></name> <name><surname>Herr&#x00E1;n</surname> <given-names>A</given-names></name><etal/></person-group> <article-title>Mental health in primary care. An epidemiological study of morbidity and use of health resources.</article-title> <source><italic>Br J Psychiatry.</italic></source> (<year>1997</year>) <volume>170</volume>:<fpage>529</fpage>&#x2013;<lpage>35</lpage>. <pub-id pub-id-type="doi">10.1192/bjp.170.6.529</pub-id> <pub-id pub-id-type="pmid">9330019</pub-id></citation></ref>
<ref id="B51"><label>51.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Zimmermann</surname> <given-names>C</given-names></name> <name><surname>Tansella</surname> <given-names>M</given-names></name></person-group>. <article-title>Psychosocial factors and physical illness in primary care: promoting the biopsychosocial model in medical practice.</article-title> <source><italic>J Psychosom Res.</italic></source> (<year>1996</year>) <volume>40</volume>:<fpage>351</fpage>&#x2013;<lpage>8</lpage>. <pub-id pub-id-type="doi">10.1016/0022-3999(95)00536-6</pub-id></citation></ref>
<ref id="B52"><label>52.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Frese</surname> <given-names>T</given-names></name> <name><surname>Hein</surname> <given-names>S</given-names></name> <name><surname>Sandholzer</surname> <given-names>H</given-names></name></person-group>. <article-title>Feasibility, understandability, and usefulness of the STEP self-rating questionnaire: results of a cross-sectional study.</article-title> <source><italic>Clin Interv Aging.</italic></source> (<year>2013</year>) <volume>8</volume>:<fpage>515</fpage>&#x2013;<lpage>21</lpage>. <pub-id pub-id-type="doi">10.2147/CIA.S41826</pub-id> <pub-id pub-id-type="pmid">23671388</pub-id></citation></ref>
<ref id="B53"><label>53.</label><citation citation-type="journal"><collab>DEGAM.</collab> <source><italic>DEGAM Fachdefinition.</italic></source> (<year>2002</year>). <comment>Available online at</comment>: <ext-link ext-link-type="uri" xlink:href="https://www.degam.de/fachdefinition.html">https://www.degam.de/fachdefinition.html</ext-link> <comment>(accessed July 6, 2021)</comment>.</citation></ref>
<ref id="B54"><label>54.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Kendrick</surname> <given-names>T</given-names></name> <name><surname>King</surname> <given-names>F</given-names></name> <name><surname>Albertella</surname> <given-names>L</given-names></name> <name><surname>Smith</surname> <given-names>P</given-names></name></person-group>. <article-title>GP treatment decisions for patients with depression: an observational study.</article-title> <source><italic>Br J Gen Pract.</italic></source> (<year>2005</year>) <volume>55</volume>:<fpage>280</fpage>&#x2013;<lpage>6</lpage>.</citation></ref>
<ref id="B55"><label>55.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Fritzsche</surname> <given-names>K</given-names></name> <name><surname>Sandholzer</surname> <given-names>H</given-names></name> <name><surname>Brucks</surname> <given-names>U</given-names></name> <name><surname>Cierpka</surname> <given-names>M</given-names></name> <name><surname>Deter</surname> <given-names>H</given-names></name> <name><surname>H&#x00E4;rter</surname> <given-names>M</given-names></name><etal/></person-group> <article-title>Psychosocial care by general practitioners&#x2014;where are the problems? Results of a demonstration project on quality management in psychosocial primary care.</article-title> <source><italic>Int J Psychiatry Med.</italic></source> (<year>1999</year>) <volume>29</volume>:<fpage>395</fpage>&#x2013;<lpage>409</lpage>. <pub-id pub-id-type="doi">10.2190/mcgf-cld4-0fre-n2uk</pub-id> <pub-id pub-id-type="pmid">10782423</pub-id></citation></ref>
<ref id="B56"><label>56.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Engert</surname> <given-names>V</given-names></name> <name><surname>Grant</surname> <given-names>J</given-names></name> <name><surname>Strauss</surname> <given-names>B</given-names></name></person-group>. <article-title>Psychosocial factors in disease and treatment&#x2014;A call for the biopsychosocial model.</article-title> <source><italic>JAMA Psychiatry.</italic></source> (<year>2020</year>) <volume>77</volume>:<fpage>996</fpage>&#x2013;<lpage>7</lpage>. <pub-id pub-id-type="doi">10.1001/jamapsychiatry.2020.0364</pub-id> <pub-id pub-id-type="pmid">32492082</pub-id></citation></ref>
<ref id="B57"><label>57.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Mercer</surname> <given-names>S</given-names></name> <name><surname>Gunn</surname> <given-names>J</given-names></name> <name><surname>Bower</surname> <given-names>P</given-names></name> <name><surname>Wyke</surname> <given-names>S</given-names></name> <name><surname>Guthrie</surname> <given-names>B</given-names></name></person-group>. <article-title>Managing patients with mental and physical multimorbidity.</article-title> <source><italic>BMJ.</italic></source> (<year>2012</year>) <volume>345</volume>:<issue>e5559</issue>. <pub-id pub-id-type="doi">10.1136/bmj.e5559</pub-id> <pub-id pub-id-type="pmid">22945951</pub-id></citation></ref>
<ref id="B58"><label>58.</label><citation citation-type="journal"><collab>World Health Organization [WHO].</collab> <source><italic>The world health report 2008: primary health care: now more than ever.</italic></source> <publisher-loc>Geneva</publisher-loc>: <publisher-name>World Health Organization</publisher-name> (<year>2008</year>). p. <fpage>119</fpage>.</citation></ref>
<ref id="B59"><label>59.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Peters</surname> <given-names>M</given-names></name> <name><surname>Godfrey</surname> <given-names>C</given-names></name> <name><surname>McInerney</surname> <given-names>P</given-names></name> <name><surname>Munn</surname> <given-names>Z</given-names></name> <name><surname>Tricco</surname> <given-names>A</given-names></name> <name><surname>Khalil</surname> <given-names>H.</given-names></name></person-group> <source><italic>&#x2018;Chapter 11: scoping reviews (2020 version)&#x2019;. JBI manual for evidence synthesis.</italic></source> <publisher-loc>Adelaide</publisher-loc>: <publisher-name>Joanna Briggs Institute</publisher-name> (<year>2020</year>).</citation></ref>
<ref id="B60"><label>60.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Tricco</surname> <given-names>A</given-names></name> <name><surname>Lillie</surname> <given-names>E</given-names></name> <name><surname>Zarin</surname> <given-names>W</given-names></name> <name><surname>O&#x2019;Brien</surname> <given-names>K</given-names></name> <name><surname>Colquhoun</surname> <given-names>H</given-names></name> <name><surname>Levac</surname> <given-names>D</given-names></name><etal/></person-group> <article-title>PRISMA extension for scoping reviews (PRISMA-ScR): checklist and explanation.</article-title> <source><italic>Ann Intern Med.</italic></source> (<year>2018</year>) <volume>169</volume>:<fpage>467</fpage>&#x2013;<lpage>73</lpage>. <pub-id pub-id-type="doi">10.7326/M18-0850</pub-id> <pub-id pub-id-type="pmid">30178033</pub-id></citation></ref>
<ref id="B61"><label>61.</label><citation citation-type="journal"><collab>OSF Registries.</collab> <source><italic>Identifying patients with psychosocial problems in general practice: a scoping review protocol.</italic></source> (<year>2021</year>). <comment>Available online at</comment>: <ext-link ext-link-type="uri" xlink:href="https://osf.io/c2m6z">https://osf.io/c2m6z</ext-link> <comment>(accessed July 6, 2021)</comment>.</citation></ref>
<ref id="B62"><label>62.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Schwenker</surname> <given-names>R</given-names></name> <name><surname>Kroeber</surname> <given-names>E</given-names></name> <name><surname>Deutsch</surname> <given-names>T</given-names></name> <name><surname>Frese</surname> <given-names>T</given-names></name> <name><surname>Unverzagt</surname> <given-names>S</given-names></name></person-group>. <article-title>Identifying patients with psychosocial problems in general practice: a scoping review protocol.</article-title> <source><italic>BMJ Open.</italic></source> (<year>2021</year>) <volume>11</volume>:<issue>e051383</issue>. <pub-id pub-id-type="doi">10.1136/bmjopen-2021-051383</pub-id> <pub-id pub-id-type="pmid">34930731</pub-id></citation></ref>
<ref id="B63"><label>63.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Boell</surname> <given-names>S</given-names></name> <name><surname>Cecez-Kecmanovic</surname> <given-names>D</given-names></name></person-group>. <article-title>A hermeneutic approach for conducting literature reviews and literature searches.</article-title> <source><italic>Commun Assoc Inf Syst.</italic></source> (<year>2014</year>) <volume>34</volume>:<issue>12</issue>. <pub-id pub-id-type="doi">10.17705/1CAIS.03412</pub-id></citation></ref>
<ref id="B64"><label>64.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Montague</surname> <given-names>J</given-names></name> <name><surname>Phillips</surname> <given-names>E</given-names></name> <name><surname>Holland</surname> <given-names>F</given-names></name> <name><surname>Archer</surname> <given-names>S</given-names></name></person-group>. <article-title>Expanding hermeneutic horizons: working as multiple researchers and with multiple participants.</article-title> <source><italic>Res Methods Med Health Sci.</italic></source> (<year>2020</year>) <volume>1</volume>:<fpage>25</fpage>&#x2013;<lpage>30</lpage>. <pub-id pub-id-type="doi">10.1177/2632084320947571</pub-id></citation></ref>
<ref id="B65"><label>65.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Freund</surname> <given-names>K</given-names></name> <name><surname>Lous</surname> <given-names>J</given-names></name></person-group>. <article-title>The effect of preventive consultations on young adults with psychosocial problems: a randomized trial.</article-title> <source><italic>Health Educ Res.</italic></source> (<year>2012</year>) <volume>27</volume>:<fpage>927</fpage>&#x2013;<lpage>45</lpage>. <pub-id pub-id-type="doi">10.1093/her/cys048</pub-id> <pub-id pub-id-type="pmid">22473217</pub-id></citation></ref>
<ref id="B66"><label>66.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Smith</surname> <given-names>P</given-names></name></person-group>. <article-title>The role of the general health questionnaire in general practice consultations.</article-title> <source><italic>Br J Gen Pract.</italic></source> (<year>1998</year>) <volume>48</volume>:<fpage>1565</fpage>&#x2013;<lpage>9</lpage>.</citation></ref>
<ref id="B67"><label>67.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>MacMillan</surname> <given-names>H</given-names></name> <name><surname>Wathen</surname> <given-names>C</given-names></name> <name><surname>Jamieson</surname> <given-names>E</given-names></name> <name><surname>Boyle</surname> <given-names>M</given-names></name> <name><surname>Shannon</surname> <given-names>H</given-names></name> <name><surname>Ford-Gilboe</surname> <given-names>M</given-names></name><etal/></person-group> <article-title>Screening for intimate partner violence in health care settings: a randomized trial.</article-title> <source><italic>JAMA.</italic></source> (<year>2009</year>) <volume>302</volume>:<fpage>493</fpage>&#x2013;<lpage>501</lpage>. <pub-id pub-id-type="doi">10.1001/jama.2009.1089</pub-id> <pub-id pub-id-type="pmid">19654384</pub-id></citation></ref>
<ref id="B68"><label>68.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Goodyear-Smith</surname> <given-names>F</given-names></name> <name><surname>Arroll</surname> <given-names>B</given-names></name> <name><surname>Coupe</surname> <given-names>N</given-names></name></person-group>. <article-title>Asking for help is helpful: validation of a brief lifestyle and mood assessment tool in primary health care.</article-title> <source><italic>Ann Fam Med.</italic></source> (<year>2009</year>) <volume>7</volume>:<fpage>239</fpage>&#x2013;<lpage>44</lpage>. <pub-id pub-id-type="doi">10.1370/afm.962</pub-id> <pub-id pub-id-type="pmid">19433841</pub-id></citation></ref>
<ref id="B69"><label>69.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Bourgois</surname> <given-names>P</given-names></name> <name><surname>Holmes</surname> <given-names>S</given-names></name> <name><surname>Sue</surname> <given-names>K</given-names></name> <name><surname>Quesada</surname> <given-names>J</given-names></name></person-group>. <article-title>Structural vulnerability: operationalizing the concept to address health disparities in clinical care.</article-title> <source><italic>Acad Med.</italic></source> (<year>2017</year>) <volume>92</volume>:<fpage>299</fpage>&#x2013;<lpage>307</lpage>. <pub-id pub-id-type="doi">10.1097/ACM.0000000000001294</pub-id> <pub-id pub-id-type="pmid">27415443</pub-id></citation></ref>
<ref id="B70"><label>70.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Thomas</surname> <given-names>H</given-names></name> <name><surname>Mitchell</surname> <given-names>G</given-names></name> <name><surname>Rich</surname> <given-names>J</given-names></name> <name><surname>Best</surname> <given-names>M</given-names></name></person-group>. <article-title>Definition of whole person care in general practice in the English language literature: a systematic review.</article-title> <source><italic>BMJ Open.</italic></source> (<year>2018</year>) <volume>8</volume>:<issue>e023758</issue>. <pub-id pub-id-type="doi">10.1136/bmjopen-2018-023758</pub-id> <pub-id pub-id-type="pmid">30552268</pub-id></citation></ref>
<ref id="B71"><label>71.</label><citation citation-type="journal"><collab>Royal College of General Practitioners [RCGP].</collab> <source><italic>Fit for the future report A vision for general practice.</italic></source> (<year>2019</year>). <comment>Available online at</comment>: <ext-link ext-link-type="uri" xlink:href="https://www.rcgp.org.uk/getmedia/ff0f6ea4-bce1-4d4e-befc-d8337db06d0e/RCGP-fit-for-the-future-report-may-2019.pdf">https://www.rcgp.org.uk/getmedia/ff0f6ea4-bce1-4d4e-befc-d8337db06d0e/RCGP-fit-for-the-future-report-may-2019.pdf</ext-link> <comment>(accessed July 18, 2022)</comment>.</citation></ref>
<ref id="B72"><label>72.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>O&#x2019;Gurek</surname> <given-names>D</given-names></name> <name><surname>Henke</surname> <given-names>CA</given-names></name></person-group>. <article-title>Practical approach to screening for social determinants of health.</article-title> <source><italic>Fam Pract Manag.</italic></source> (<year>2018</year>) <volume>25</volume>:<fpage>7</fpage>&#x2013;<lpage>12</lpage>.</citation></ref>
<ref id="B73"><label>73.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Billioux</surname> <given-names>A</given-names></name> <name><surname>Verlander</surname> <given-names>K</given-names></name> <name><surname>Anthony</surname> <given-names>S</given-names></name> <name><surname>Alley</surname> <given-names>D</given-names></name></person-group>. <article-title>Centers for medicare and medicaid services. Standardized screening for health-related social needs in clinical settings: the accountable health communities screening tool.</article-title> <source><italic>NAM Perspect.</italic></source> (<year>2017</year>) <volume>7</volume>:1&#x2013;9. <pub-id pub-id-type="doi">10.31478/201705b</pub-id> <pub-id pub-id-type="pmid">32461272</pub-id></citation></ref>
<ref id="B74"><label>74.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Fiorillo</surname> <given-names>A</given-names></name> <name><surname>Gorwood</surname> <given-names>P</given-names></name></person-group>. <article-title>The consequences of the COVID-19 pandemic on mental health and implications for clinical practice.</article-title> <source><italic>Eur Psychiatry.</italic></source> (<year>2020</year>) <volume>63</volume>:<issue>e32</issue>. <pub-id pub-id-type="doi">10.1192/j.eurpsy.2020.35</pub-id> <pub-id pub-id-type="pmid">32234102</pub-id></citation></ref>
<ref id="B75"><label>75.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Brooks</surname> <given-names>S</given-names></name> <name><surname>Webster</surname> <given-names>R</given-names></name> <name><surname>Smith</surname> <given-names>L</given-names></name> <name><surname>Woodland</surname> <given-names>L</given-names></name> <name><surname>Wessely</surname> <given-names>S</given-names></name> <name><surname>Greenberg</surname> <given-names>N</given-names></name><etal/></person-group> <article-title>The psychological impact of quarantine and how to reduce it: rapid review of the evidence.</article-title> <source><italic>Lancet.</italic></source> (<year>2020</year>) <volume>395</volume>:<fpage>912</fpage>&#x2013;<lpage>20</lpage>. <pub-id pub-id-type="doi">10.1016/S0140-6736(20)30460-8</pub-id></citation></ref>
<ref id="B76"><label>76.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Moreno</surname> <given-names>C</given-names></name> <name><surname>Wykes</surname> <given-names>T</given-names></name> <name><surname>Galderisi</surname> <given-names>S</given-names></name> <name><surname>Nordentoft</surname> <given-names>M</given-names></name> <name><surname>Crossley</surname> <given-names>N</given-names></name> <name><surname>Jones</surname> <given-names>N</given-names></name><etal/></person-group> <article-title>How mental health care should change as a consequence of the COVID-19 pandemic.</article-title> <source><italic>Lancet Psychiatry.</italic></source> (<year>2020</year>) <volume>7</volume>:<fpage>813</fpage>&#x2013;<lpage>24</lpage>. <pub-id pub-id-type="doi">10.1016/s2215-0366(20)30307-2</pub-id></citation></ref>
<ref id="B77"><label>77.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Webb</surname> <given-names>M</given-names></name> <name><surname>Sanci</surname> <given-names>L</given-names></name> <name><surname>Kauer</surname> <given-names>S</given-names></name> <name><surname>Wadley</surname> <given-names>G</given-names></name></person-group>. <article-title>Designing a health screening tool to help young people communicate with their general practitioner.</article-title> In: <source><italic>Proceedings of the annual meeting of the Australian special interest group for computer human interaction.</italic></source> <publisher-loc>Parkville</publisher-loc> (2015). <fpage>p. 124</fpage>&#x2013;<lpage>33</lpage>. <pub-id pub-id-type="doi">10.1145/2838739.2838756</pub-id></citation></ref>
<ref id="B78"><label>78.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Blom</surname> <given-names>J</given-names></name> <name><surname>den Elzen</surname> <given-names>W</given-names></name> <name><surname>van Houwelingen</surname> <given-names>A</given-names></name> <name><surname>Heijmans</surname> <given-names>M</given-names></name> <name><surname>Stijnen</surname> <given-names>T</given-names></name> <name><surname>Van den Hout</surname> <given-names>W</given-names></name><etal/></person-group> <article-title>Effectiveness and cost-effectiveness of a proactive, goal-oriented, integrated care model in general practice for older people. A cluster randomised controlled trial: integrated systematic care for older people&#x2014;the ISCOPE study.</article-title> <source><italic>Age Ageing.</italic></source> (<year>2016</year>) <volume>45</volume>:<fpage>30</fpage>&#x2013;<lpage>41</lpage>. <pub-id pub-id-type="doi">10.1093/ageing/afv174</pub-id> <pub-id pub-id-type="pmid">26764392</pub-id></citation></ref>
<ref id="B79"><label>79.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Geyti</surname> <given-names>C</given-names></name> <name><surname>Christensen</surname> <given-names>K</given-names></name> <name><surname>Dalsgaard</surname> <given-names>E</given-names></name> <name><surname>Bech</surname> <given-names>B</given-names></name> <name><surname>Gunn</surname> <given-names>J</given-names></name> <name><surname>Maindal</surname> <given-names>H</given-names></name><etal/></person-group> <article-title>Factors associated with non-initiation of mental healthcare after detection of poor mental health at a scheduled health check: a cohort study.</article-title> <source><italic>BMJ Open.</italic></source> (<year>2020</year>) <volume>10</volume>:<issue>e037731</issue>. <pub-id pub-id-type="doi">10.1136/bmjopen-2020-037731</pub-id> <pub-id pub-id-type="pmid">33067280</pub-id></citation></ref>
<ref id="B80"><label>80.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Kloppe</surname> <given-names>T</given-names></name> <name><surname>Tetzlaff</surname> <given-names>B</given-names></name> <name><surname>Mews</surname> <given-names>C</given-names></name> <name><surname>Zimmermann</surname> <given-names>T</given-names></name> <name><surname>Scherer</surname> <given-names>M</given-names></name></person-group>. <article-title>Interprofessional collaboration to support patients with social problems in general practice&#x2014;a qualitative focus group study.</article-title> <source><italic>BMC Prim Care.</italic></source> (<year>2022</year>) <volume>23</volume>:<issue>169</issue>. <pub-id pub-id-type="doi">10.1186/s12875-022-01782-z</pub-id> <pub-id pub-id-type="pmid">35788186</pub-id></citation></ref>
<ref id="B81"><label>81.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>L&#x00F6;we</surname> <given-names>C</given-names></name> <name><surname>Mark</surname> <given-names>P</given-names></name> <name><surname>Sommer</surname> <given-names>S</given-names></name> <name><surname>Weltermann</surname> <given-names>B</given-names></name></person-group>. <article-title>Collaboration between general practitioners and social workers: a scoping review.</article-title> <source><italic>BMJ Open.</italic></source> (<year>2022</year>) <volume>12</volume>:<issue>e062144</issue>. <pub-id pub-id-type="doi">10.1136/bmjopen-2022-062144</pub-id> <pub-id pub-id-type="pmid">36691249</pub-id></citation></ref>
<ref id="B82"><label>82.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Stumm</surname> <given-names>J</given-names></name> <name><surname>Peter</surname> <given-names>L</given-names></name> <name><surname>Sonntag</surname> <given-names>U</given-names></name> <name><surname>K&#x00FC;mpel</surname> <given-names>L</given-names></name> <name><surname>Heintze</surname> <given-names>C</given-names></name> <name><surname>D&#x00F6;pfmer</surname> <given-names>S</given-names></name></person-group>. <article-title>Nichtmedizinische Aspekte der Versorgung multimorbider Patient&#x002A;innen in der Hausarztpraxis. Welche Unterst&#x00FC;tzung und Kooperationen werden gew&#x00FC;nscht? Fokusgruppen mit Berliner Haus&#x00E4;rzt&#x002A;innen. [Non-medical aspects in the care for multimorbid patients in general practice. What kind of support and cooperation is desired? Focus groups with general practitioners in Berlin].</article-title> <source><italic>Z Evid Fortbild Qual Gesundhwes.</italic></source> (<year>2020</year>) <volume>158&#x2013;59</volume>:<fpage>66</fpage>&#x2013;<lpage>73</lpage>. <pub-id pub-id-type="doi">10.1016/j.zefq.2020.09.001</pub-id> <pub-id pub-id-type="pmid">33187897</pub-id></citation></ref>
<ref id="B83"><label>83.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>McGregor</surname> <given-names>J</given-names></name> <name><surname>Mercer</surname> <given-names>S</given-names></name> <name><surname>Harris</surname> <given-names>F</given-names></name></person-group>. <article-title>Health benefits of primary care social work for adults with complex health and social needs: a systematic review.</article-title> <source><italic>Health Soc Care Community.</italic></source> (<year>2018</year>) <volume>26</volume>:<fpage>1</fpage>&#x2013;<lpage>13</lpage>. <pub-id pub-id-type="doi">10.1111/hsc.12337</pub-id> <pub-id pub-id-type="pmid">27059167</pub-id></citation></ref>
<ref id="B84"><label>84.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>D&#x00F6;bl</surname> <given-names>S</given-names></name> <name><surname>Huggard</surname> <given-names>P</given-names></name> <name><surname>Beddoe</surname> <given-names>L</given-names></name></person-group>. <article-title>A hidden jewel: social work in primary health care practice in Aotearoa New Zealand.</article-title> <source><italic>J Prim Health Care.</italic></source> (<year>2015</year>) <volume>7</volume>:<fpage>333</fpage>&#x2013;<lpage>8</lpage>. <pub-id pub-id-type="doi">10.1071/hc15333</pub-id> <pub-id pub-id-type="pmid">26668839</pub-id></citation></ref>
<ref id="B85"><label>85.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Fitch</surname> <given-names>K</given-names></name> <name><surname>Bernstein</surname> <given-names>S</given-names></name> <name><surname>Aguilar</surname> <given-names>M</given-names></name> <name><surname>Burnand</surname> <given-names>B</given-names></name> <name><surname>LaCalle</surname> <given-names>J</given-names></name> <name><surname>L&#x00E1;zaro</surname> <given-names>P</given-names></name><etal/></person-group> <source><italic>The RAND/UCLA appropriateness method user&#x2019;s manual.</italic></source> <publisher-loc>Santa Monica, CA</publisher-loc>: <publisher-name>RAND</publisher-name> (<year>2001</year>).</citation></ref>
<ref id="B86"><label>86.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>McBride</surname> <given-names>K</given-names></name> <name><surname>MacMillan</surname> <given-names>F</given-names></name> <name><surname>George</surname> <given-names>E</given-names></name> <name><surname>Steiner</surname> <given-names>G</given-names></name></person-group>. <article-title>The use of mixed methods in research.</article-title> In: <person-group person-group-type="editor"><name><surname>Liamputtong</surname> <given-names>P</given-names></name></person-group> <role>editor.</role> <source><italic>Handbook of research methods in health social sciences.</italic></source> <publisher-loc>Singapore</publisher-loc>: <publisher-name>Springer</publisher-name> (<year>2019</year>). <fpage>p. 695</fpage>&#x2013;<lpage>713</lpage>. <pub-id pub-id-type="doi">10.1007/978-981-10-5251-4_97</pub-id></citation></ref>
<ref id="B87"><label>87.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Hopton</surname> <given-names>J</given-names></name> <name><surname>Hunt</surname> <given-names>S</given-names></name> <name><surname>Shiels</surname> <given-names>C</given-names></name> <name><surname>Smith</surname> <given-names>C</given-names></name></person-group>. <article-title>Measuring psychological well-being. The adapted general well-being index in a primary care setting: a test of validity.</article-title> <source><italic>Fam Pract.</italic></source> (<year>1995</year>) <volume>12</volume>:<fpage>452</fpage>&#x2013;<lpage>60</lpage>. <pub-id pub-id-type="doi">10.1093/fampra/12.4.452</pub-id> <pub-id pub-id-type="pmid">8826065</pub-id></citation></ref>
<ref id="B88"><label>88.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Goodyear-Smith</surname> <given-names>F</given-names></name> <name><surname>Coupe</surname> <given-names>N</given-names></name> <name><surname>Arroll</surname> <given-names>B</given-names></name> <name><surname>Elley</surname> <given-names>C</given-names></name> <name><surname>Sullivan</surname> <given-names>S</given-names></name> <name><surname>McGill</surname> <given-names>A</given-names></name></person-group>. <article-title>Case finding of lifestyle and mental health disorders in primary care: validation of the &#x2018;CHAT&#x2019; tool.</article-title> <source><italic>Br J Gen Pract.</italic></source> (<year>2008</year>) <volume>58</volume>:<fpage>26</fpage>&#x2013;<lpage>31</lpage>. <pub-id pub-id-type="doi">10.3399/bjgp08X263785</pub-id> <pub-id pub-id-type="pmid">18186993</pub-id></citation></ref>
<ref id="B89"><label>89.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Deli&#x00E8;ge</surname> <given-names>DA</given-names></name></person-group>. <article-title>A classification system of social problems: concepts and influence on GPs&#x2019; registration of problems.</article-title> <source><italic>Soc Work Health Care.</italic></source> (<year>2001</year>) <volume>34</volume>:<fpage>195</fpage>&#x2013;<lpage>238</lpage>. <pub-id pub-id-type="doi">10.1080/00981380109517026</pub-id> <pub-id pub-id-type="pmid">12219767</pub-id></citation></ref>
<ref id="B90"><label>90.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Goodyear-Smith</surname> <given-names>F</given-names></name> <name><surname>Warren</surname> <given-names>J</given-names></name> <name><surname>Bojic</surname> <given-names>M</given-names></name> <name><surname>Chong</surname> <given-names>A</given-names></name></person-group>. <article-title>eCHAT for lifestyle and mental health screening in primary care.</article-title> <source><italic>Ann Fam Med.</italic></source> (<year>2013</year>) <volume>11</volume>:<fpage>460</fpage>&#x2013;<lpage>6</lpage>. <pub-id pub-id-type="doi">10.1370/afm.1512</pub-id> <pub-id pub-id-type="pmid">24019278</pub-id></citation></ref>
<ref id="B91"><label>91.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Hase</surname> <given-names>H</given-names></name> <name><surname>Luger</surname> <given-names>J</given-names></name></person-group>. <article-title>Screening for psychosocial problems in primary care.</article-title> <source><italic>J Fam Pract.</italic></source> (<year>1988</year>) <volume>26</volume>:<fpage>297</fpage>&#x2013;<lpage>302</lpage>.</citation></ref>
<ref id="B92"><label>92.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Tak</surname> <given-names>E</given-names></name> <name><surname>van Hespen</surname> <given-names>A</given-names></name> <name><surname>Verhaak</surname> <given-names>P</given-names></name> <name><surname>Eekhof</surname> <given-names>J</given-names></name> <name><surname>Hopman-Rock</surname> <given-names>M</given-names></name></person-group>. <article-title>Development and preliminary validation of an observation list for detecting mental disorders and social problems in the elderly in primary and home care (OLP).</article-title> <source><italic>Int J Geriatr Psychiatry.</italic></source> (<year>2016</year>) <volume>31</volume>:<fpage>755</fpage>&#x2013;<lpage>64</lpage>. <pub-id pub-id-type="doi">10.1002/gps.4388</pub-id> <pub-id pub-id-type="pmid">26556009</pub-id></citation></ref>
<ref id="B93"><label>93.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Hilliard</surname> <given-names>R</given-names></name> <name><surname>Gjerde</surname> <given-names>C</given-names></name> <name><surname>Parker</surname> <given-names>L</given-names></name></person-group>. <article-title>Validity of two psychological screening measures in family practice: personal inventory and family APGAR.</article-title> <source><italic>J Fam Pract.</italic></source> (<year>1986</year>) <volume>23</volume>:<fpage>345</fpage>&#x2013;<lpage>9</lpage>. <pub-id pub-id-type="pmid">3760796</pub-id></citation></ref>
<ref id="B94"><label>94.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>King</surname> <given-names>M</given-names></name> <name><surname>Nazareth</surname> <given-names>I</given-names></name></person-group>. <article-title>The health of people classified as lesbian, gay and bisexual attending family practitioners in London: a controlled study.</article-title> <source><italic>BMC Public Health.</italic></source> (<year>2006</year>) <volume>6</volume>:<issue>127</issue>. <pub-id pub-id-type="doi">10.1186/1471-2458-6-127</pub-id> <pub-id pub-id-type="pmid">16681849</pub-id></citation></ref>
<ref id="B95"><label>95.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Schreuders</surname> <given-names>B</given-names></name> <name><surname>van Marwijk</surname> <given-names>H</given-names></name> <name><surname>Smit</surname> <given-names>J</given-names></name> <name><surname>Rijmen</surname> <given-names>F</given-names></name> <name><surname>Stalman</surname> <given-names>W</given-names></name> <name><surname>van Oppen</surname> <given-names>P</given-names></name></person-group>. <article-title>Primary care patients with mental health problems: outcome of a randomised clinical trial.</article-title> <source><italic>Br J Gen Pract.</italic></source> (<year>2007</year>) <volume>57</volume>:<fpage>886</fpage>&#x2013;<lpage>91</lpage>. <pub-id pub-id-type="doi">10.3399/096016407782317829</pub-id> <pub-id pub-id-type="pmid">17976289</pub-id></citation></ref>
<ref id="B96"><label>96.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Hegarty</surname> <given-names>K</given-names></name> <name><surname>O&#x2019;Doherty</surname> <given-names>L</given-names></name> <name><surname>Taft</surname> <given-names>A</given-names></name> <name><surname>Chondros</surname> <given-names>P</given-names></name> <name><surname>Brown</surname> <given-names>S</given-names></name> <name><surname>Valpied</surname> <given-names>J</given-names></name><etal/></person-group> <article-title>Screening and counselling in the primary care setting for women who have experienced intimate partner violence (WEAVE): a cluster randomised controlled trial.</article-title> <source><italic>Lancet.</italic></source> (<year>2013</year>) <volume>382</volume>:<fpage>249</fpage>&#x2013;<lpage>58</lpage>. <pub-id pub-id-type="doi">10.1016/S0140-6736(13)60052-5</pub-id></citation></ref>
<ref id="B97"><label>97.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Geyti</surname> <given-names>C</given-names></name> <name><surname>Dalsgaard</surname> <given-names>E</given-names></name> <name><surname>Sandb&#x00E6;k</surname> <given-names>A</given-names></name> <name><surname>Maindal</surname> <given-names>H</given-names></name> <name><surname>Christensen</surname> <given-names>K</given-names></name></person-group>. <article-title>Initiation and cessation of mental healthcare after mental health screening in primary care: a prospective cohort study.</article-title> <source><italic>BMC Fam Pract.</italic></source> (<year>2018</year>) <volume>19</volume>:<issue>176</issue>. <pub-id pub-id-type="doi">10.1186/s12875-018-0864-9</pub-id> <pub-id pub-id-type="pmid">30447688</pub-id></citation></ref>
<ref id="B98"><label>98.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Raine</surname> <given-names>R</given-names></name> <name><surname>Lewis</surname> <given-names>L</given-names></name> <name><surname>Sensky</surname> <given-names>T</given-names></name> <name><surname>Hutchings</surname> <given-names>A</given-names></name> <name><surname>Hirsch</surname> <given-names>S</given-names></name> <name><surname>Black</surname> <given-names>N</given-names></name></person-group>. <article-title>Patient determinants of mental health interventions in primary care.</article-title> <source><italic>Br J Gen Pract.</italic></source> (<year>2000</year>) <volume>50</volume>:<fpage>620</fpage>&#x2013;<lpage>5</lpage>.</citation></ref>
<ref id="B99"><label>99.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Hassink-Franke</surname> <given-names>L</given-names></name> <name><surname>van Weel-Baumgarten</surname> <given-names>E</given-names></name> <name><surname>Wierda</surname> <given-names>E</given-names></name> <name><surname>Engelen</surname> <given-names>M</given-names></name> <name><surname>Beek</surname> <given-names>ML</given-names></name> <name><surname>Bor</surname> <given-names>H</given-names></name><etal/></person-group> <article-title>Effectiveness of problem-solving treatment by general practice registrars for patients with emotional symptoms.</article-title> <source><italic>J Prim Health Care.</italic></source> (<year>2011</year>) <volume>3</volume>:<fpage>181</fpage>&#x2013;<lpage>9</lpage>. <pub-id pub-id-type="doi">10.1071/hc11181</pub-id></citation></ref>
<ref id="B100"><label>100.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Sanci</surname> <given-names>L</given-names></name> <name><surname>Chondros</surname> <given-names>P</given-names></name> <name><surname>Sawyer</surname> <given-names>S</given-names></name> <name><surname>Pirkis</surname> <given-names>J</given-names></name> <name><surname>Ozer</surname> <given-names>E</given-names></name> <name><surname>Hegarty</surname> <given-names>K</given-names></name><etal/></person-group> <article-title>Responding to young people&#x2019;s health risks in primary care: a cluster randomised trial of training clinicians in screening and motivational interviewing.</article-title> <source><italic>PLoS One.</italic></source> (<year>2015</year>) <volume>10</volume>:<issue>e0137581</issue>. <pub-id pub-id-type="doi">10.1371/journal.pone.0137581</pub-id> <pub-id pub-id-type="pmid">26422235</pub-id></citation></ref>
<ref id="B101"><label>101.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>De La Revilla</surname> <given-names>L</given-names></name> <name><surname>Zurita</surname> <given-names>R</given-names></name> <name><surname>De Los R&#x00ED;os</surname> <given-names>A</given-names></name> <name><surname>Castro</surname> <given-names>J</given-names></name></person-group>. <article-title>Un m&#x00E9;todo de detecci&#x00F3;n de problemas psicosociales en la consulta del m&#x00E9;dico de familia.</article-title> <source><italic>Aten Primaria.</italic></source> (<year>1997</year>) <volume>19</volume>:<fpage>133</fpage>&#x2013;<lpage>7</lpage>.</citation></ref>
<ref id="B102"><label>102.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Vidotto</surname> <given-names>G</given-names></name> <name><surname>Ferrario</surname> <given-names>S</given-names></name> <name><surname>Bond</surname> <given-names>T</given-names></name> <name><surname>Zotti</surname> <given-names>A</given-names></name></person-group>. <article-title>Family strain questionnaire&#x2014;short form for nurses and general practitioners.</article-title> <source><italic>J Clin Nurs.</italic></source> (<year>2010</year>) <volume>19</volume>:<fpage>275</fpage>&#x2013;<lpage>83</lpage>. <pub-id pub-id-type="doi">10.1111/j.1365-2702.2009.02965.x</pub-id> <pub-id pub-id-type="pmid">20500263</pub-id></citation></ref>
<ref id="B103"><label>103.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Stefansson</surname> <given-names>C</given-names></name> <name><surname>Svensson</surname> <given-names>C</given-names></name></person-group>. <article-title>Identified and unidentified mental illness in primary health care&#x2014;social characteristics, medical measures and total care utilization during one year.</article-title> <source><italic>Scand J Prim Health Care.</italic></source> (<year>1994</year>) <volume>12</volume>:<fpage>24</fpage>&#x2013;<lpage>31</lpage>. <pub-id pub-id-type="doi">10.3109/02813439408997053</pub-id> <pub-id pub-id-type="pmid">8009096</pub-id></citation></ref>
<ref id="B104"><label>104.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Wasson</surname> <given-names>J</given-names></name> <name><surname>Jette</surname> <given-names>A</given-names></name> <name><surname>Anderson</surname> <given-names>J</given-names></name> <name><surname>Johnson</surname> <given-names>D</given-names></name> <name><surname>Nelson</surname> <given-names>E</given-names></name> <name><surname>Kilo</surname> <given-names>C</given-names></name></person-group>. <article-title>Routine, single-item screening to identify abusive relationships in women.</article-title> <source><italic>J Fam Pract.</italic></source> (<year>2000</year>) <volume>49</volume>:<fpage>1017</fpage>&#x2013;<lpage>22</lpage>. <pub-id pub-id-type="pmid">11093568</pub-id></citation></ref>
<ref id="B105"><label>105.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Cook</surname> <given-names>C</given-names></name> <name><surname>Freedman</surname> <given-names>J</given-names></name> <name><surname>Freedman</surname> <given-names>L</given-names></name> <name><surname>Arick</surname> <given-names>R</given-names></name> <name><surname>Miller</surname> <given-names>M</given-names></name></person-group>. <article-title>Screening for social and environmental problems in a VA primary care setting.</article-title> <source><italic>Health Soc Work.</italic></source> (<year>1996</year>) <volume>21</volume>:<fpage>41</fpage>&#x2013;<lpage>7</lpage>. <pub-id pub-id-type="doi">10.1093/hsw/21.1.41</pub-id> <pub-id pub-id-type="pmid">8626157</pub-id></citation></ref>
<ref id="B106"><label>106.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Al-Shammari</surname> <given-names>S</given-names></name></person-group>. <article-title>Screening for psychosocial problems among primary care patients in Riyadh, Saudi Arabia.</article-title> <source><italic>Int J Ment Health.</italic></source> (<year>1994</year>) <volume>23</volume>:<fpage>69</fpage>&#x2013;<lpage>80</lpage>. <pub-id pub-id-type="doi">10.1080/00207411.1994.11449294</pub-id></citation></ref>
<ref id="B107"><label>107.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Saltini</surname> <given-names>A</given-names></name> <name><surname>Mazzi</surname> <given-names>M</given-names></name> <name><surname>Del Piccolo</surname> <given-names>L</given-names></name> <name><surname>Zimmermann</surname> <given-names>C</given-names></name></person-group>. <article-title>Decisional strategies for the attribution of emotional distress in primary care.</article-title> <source><italic>Psychol Med.</italic></source> (<year>2004</year>) <volume>34</volume>:<fpage>729</fpage>&#x2013;<lpage>39</lpage>. <pub-id pub-id-type="doi">10.1017/S0033291703001260</pub-id> <pub-id pub-id-type="pmid">15099426</pub-id></citation></ref>
<ref id="B108"><label>108.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Terluin</surname> <given-names>B</given-names></name> <name><surname>van Marwijk</surname> <given-names>H</given-names></name> <name><surname>Ad&#x00E8;r</surname> <given-names>H</given-names></name> <name><surname>de Vet</surname> <given-names>H</given-names></name> <name><surname>Penninx</surname> <given-names>B</given-names></name> <name><surname>Hermens</surname> <given-names>M</given-names></name><etal/></person-group> <article-title>The four-dimensional symptom questionnaire (4DSQ): a validation study of a multidimensional self-report questionnaire to assess distress, depression, anxiety and somatization.</article-title> <source><italic>BMC Psychiatry.</italic></source> (<year>2006</year>) <volume>6</volume>:<issue>34</issue>. <pub-id pub-id-type="doi">10.1186/1471-244X-6-34</pub-id> <pub-id pub-id-type="pmid">16925825</pub-id></citation></ref>
<ref id="B109"><label>109.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Van der Pasch</surname> <given-names>M</given-names></name> <name><surname>Verhaak</surname> <given-names>P</given-names></name></person-group>. <article-title>Communication in general practice: recognition and treatment of mental illness.</article-title> <source><italic>Patient Educ Couns.</italic></source> (<year>1998</year>) <volume>33</volume>:<fpage>97</fpage>&#x2013;<lpage>112</lpage>. <pub-id pub-id-type="doi">10.1016/s0738-3991(97)00057-8</pub-id></citation></ref>
<ref id="B110"><label>110.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Kapur</surname> <given-names>N</given-names></name> <name><surname>Hunt</surname> <given-names>I</given-names></name> <name><surname>Lunt</surname> <given-names>M</given-names></name> <name><surname>McBeth</surname> <given-names>J</given-names></name> <name><surname>Creed</surname> <given-names>F</given-names></name> <name><surname>Macfarlane</surname> <given-names>G</given-names></name></person-group>. <article-title>Psychosocial and illness related predictors of consultation rates in primary care&#x2014;a cohort study.</article-title> <source><italic>Psychol Med.</italic></source> (<year>2004</year>) <volume>34</volume>:<fpage>719</fpage>&#x2013;<lpage>28</lpage>. <pub-id pub-id-type="doi">10.1017/S0033291703001223</pub-id> <pub-id pub-id-type="pmid">15099425</pub-id></citation></ref>
<ref id="B111"><label>111.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Kendrick</surname> <given-names>T</given-names></name> <name><surname>Simons</surname> <given-names>L</given-names></name> <name><surname>Mynors-Wallis</surname> <given-names>L</given-names></name> <name><surname>Gray</surname> <given-names>A</given-names></name> <name><surname>Lathlean</surname> <given-names>J</given-names></name> <name><surname>Pickering</surname> <given-names>R</given-names></name><etal/></person-group> <article-title>A trial of problem-solving by community mental health nurses for anxiety, depression and life difficulties among general practice patients. The CPN-GP study.</article-title> <source><italic>Health Technol Assess.</italic></source> (<year>2005</year>) <volume>9</volume>:<fpage>1</fpage>&#x2013;<lpage>104</lpage>. <pub-id pub-id-type="doi">10.3310/hta9370</pub-id> <pub-id pub-id-type="pmid">16153354</pub-id></citation></ref>
<ref id="B112"><label>112.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Mirza</surname> <given-names>I</given-names></name> <name><surname>Hassan</surname> <given-names>R</given-names></name> <name><surname>Chaudhary</surname> <given-names>H</given-names></name> <name><surname>Jenkins</surname> <given-names>R</given-names></name></person-group>. <article-title>Eliciting explanatory models of common mental disorders using the short explanatory model interview (SEMI) urdu adaptation&#x2014;a pilot study.</article-title> <source><italic>J Pak Med Assoc.</italic></source> (<year>2006</year>) <volume>56</volume>:<fpage>461</fpage>&#x2013;<lpage>3</lpage>. <pub-id pub-id-type="pmid">17144394</pub-id></citation></ref>
<ref id="B113"><label>113.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Gon&#x00E7;alves</surname> <given-names>D</given-names></name> <name><surname>Fortes</surname> <given-names>S</given-names></name> <name><surname>T&#x00F3;foli</surname> <given-names>L</given-names></name> <name><surname>Campos</surname> <given-names>M</given-names></name> <name><surname>Mari Jde</surname> <given-names>J</given-names></name></person-group>. <article-title>Determinants of common mental disorders detection by general practitioners in primary health care in Brazil.</article-title> <source><italic>Int J Psychiatry Med.</italic></source> (<year>2011</year>) <volume>41</volume>:<fpage>3</fpage>&#x2013;<lpage>13</lpage>. <pub-id pub-id-type="doi">10.2190/PM.41.1.b</pub-id> <pub-id pub-id-type="pmid">21495518</pub-id></citation></ref>
<ref id="B114"><label>114.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Shiber</surname> <given-names>A</given-names></name> <name><surname>Maoz</surname> <given-names>B</given-names></name> <name><surname>Antonovsky</surname> <given-names>A</given-names></name> <name><surname>Antonovsky</surname> <given-names>H</given-names></name></person-group>. <article-title>Detection of emotional problems in the primary care clinic.</article-title> <source><italic>Fam Pract.</italic></source> (<year>1990</year>) <volume>7</volume>:<fpage>195</fpage>&#x2013;<lpage>200</lpage>. <pub-id pub-id-type="doi">10.1093/fampra/7.3.195</pub-id> <pub-id pub-id-type="pmid">2245890</pub-id></citation></ref>
<ref id="B115"><label>115.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Watts</surname> <given-names>S</given-names></name> <name><surname>Bhutani</surname> <given-names>G</given-names></name> <name><surname>Stout</surname> <given-names>I</given-names></name> <name><surname>Ducker</surname> <given-names>G</given-names></name> <name><surname>Cleator</surname> <given-names>P</given-names></name> <name><surname>McGarry</surname> <given-names>J</given-names></name><etal/></person-group> <article-title>Mental health in older adult recipients of primary care services: is depression the key issue? Identification, treatment and the general practitioner.</article-title> <source><italic>Int J Geriatr Psychiatry.</italic></source> (<year>2002</year>) <volume>17</volume>:<fpage>427</fpage>&#x2013;<lpage>37</lpage>. <pub-id pub-id-type="doi">10.1002/gps.632</pub-id> <pub-id pub-id-type="pmid">11994931</pub-id></citation></ref>
<ref id="B116"><label>116.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>de la Revilla Ahumada</surname> <given-names>L</given-names></name> <name><surname>de los R&#x00ED;os Alvarez</surname> <given-names>A</given-names></name> <name><surname>Luna del Castillo</surname> <given-names>J</given-names></name></person-group>. <article-title>Use of the goldberg general health questionnaire (GHQ-28) to detect psychosocial problems in the family physician&#x2019;s office.</article-title> <source><italic>Aten Primaria.</italic></source> (<year>2004</year>) <volume>33</volume>:<fpage>417</fpage>&#x2013;<lpage>22; discussion 423&#x2013;5</lpage>. <pub-id pub-id-type="doi">10.1016/s0212-6567(04)79426-3</pub-id></citation></ref>
<ref id="B117"><label>117.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Rabinowitz</surname> <given-names>J</given-names></name> <name><surname>Shayevitz</surname> <given-names>D</given-names></name> <name><surname>Hornik</surname> <given-names>T</given-names></name> <name><surname>Feldman</surname> <given-names>D</given-names></name></person-group>. <article-title>Primary care physicians&#x2019; detection of psychological distress among elderly patients.</article-title> <source><italic>Am J Geriatr Psychiatry.</italic></source> (<year>2005</year>) <volume>13</volume>:<fpage>773</fpage>&#x2013;<lpage>80</lpage>. <pub-id pub-id-type="doi">10.1097/00019442-200509000-00005</pub-id></citation></ref>
<ref id="B118"><label>118.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Verhaak</surname> <given-names>P</given-names></name> <name><surname>Wennink</surname> <given-names>H</given-names></name> <name><surname>Tijhuis</surname> <given-names>M</given-names></name></person-group>. <article-title>The importance of the GHQ in general practice.</article-title> <source><italic>Fam Pract.</italic></source> (<year>1990</year>) <volume>7</volume>:<fpage>319</fpage>&#x2013;<lpage>24</lpage>. <pub-id pub-id-type="doi">10.1093/fampra/7.4.319</pub-id> <pub-id pub-id-type="pmid">2289646</pub-id></citation></ref>
<ref id="B119"><label>119.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Verhaak</surname> <given-names>P</given-names></name> <name><surname>Tijhuis</surname> <given-names>M</given-names></name></person-group>. <article-title>Psychosocial problems in primary care: some results from the dutch national study of morbidity and interventions in general practice.</article-title> <source><italic>Soc Sci Med.</italic></source> (<year>1992</year>) <volume>35</volume>:<fpage>105</fpage>&#x2013;<lpage>10</lpage>. <pub-id pub-id-type="doi">10.1016/0277-9536(92)90157-l</pub-id></citation></ref>
<ref id="B120"><label>120.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Odell</surname> <given-names>S</given-names></name> <name><surname>Surtees</surname> <given-names>P</given-names></name> <name><surname>Wainwright</surname> <given-names>N</given-names></name> <name><surname>Commander</surname> <given-names>M</given-names></name> <name><surname>Sashidharan</surname> <given-names>S</given-names></name></person-group>. <article-title>Determinants of general practitioner recognition of psychological problems in a multi-ethnic inner-city health district.</article-title> <source><italic>Br J Psychiatry.</italic></source> (<year>1997</year>) <volume>171</volume>:<fpage>537</fpage>&#x2013;<lpage>41</lpage>. <pub-id pub-id-type="doi">10.1192/bjp.171.6.537</pub-id> <pub-id pub-id-type="pmid">9519092</pub-id></citation></ref>
<ref id="B121"><label>121.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Corser</surname> <given-names>C</given-names></name> <name><surname>Philip</surname> <given-names>A</given-names></name></person-group>. <article-title>Emotional disturbance in newly registered general practice patients.</article-title> <source><italic>Br J Psychiatry.</italic></source> (<year>1978</year>) <volume>132</volume>:<fpage>172</fpage>&#x2013;<lpage>6</lpage>. <pub-id pub-id-type="doi">10.1192/bjp.132.2.172</pub-id> <pub-id pub-id-type="pmid">623951</pub-id></citation></ref>
<ref id="B122"><label>122.</label><citation citation-type="journal"><person-group person-group-type="author"><name><surname>Martinez</surname> <given-names>R</given-names></name> <name><surname>Reynolds</surname> <given-names>S</given-names></name> <name><surname>Howe</surname> <given-names>A</given-names></name></person-group>. <article-title>Factors that influence the detection of psychological problems in adolescents attending general practices.</article-title> <source><italic>Br J Gen Pract.</italic></source> (<year>2006</year>) <volume>56</volume>:<fpage>594</fpage>&#x2013;<lpage>9</lpage>.</citation></ref>
</ref-list>
</back>
</article>