AUTHOR=Corrà Alberto , Verdelli Alice , Mariotti Elena Biancamaria , Ruffo di Calabria Valentina , Quintarelli Lavinia , Aimo Cristina , Sunderkötter Cord H. , Caproni Marzia 

TITLE=Cutaneous vasculitis: Lessons from COVID-19 and COVID-19 vaccination

JOURNAL=Frontiers in Medicine

VOLUME=Volume 9 - 2022

YEAR=2022

URL=https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2022.1013846

DOI=10.3389/fmed.2022.1013846

ISSN=2296-858X

ABSTRACT=Cutaneous vasculitis are inflammatory skin-limited vascular disease affecting dermal and/or hypodermal vessel wall. From the pathogenetic point of view, idiopathic forms are described as well as the induction from various triggers, such as drugs, infections or vaccines. Following SARS-CoV-2 pandemic outbreak, cases of cutaneous vasculitis induced by both COVID-19 and COVID-19 vaccinations have been reported in literature. The aim of our work is collecting multiple cases available in literature, analyzing the frequency of the different forms of induced vasculitis, as well as their histological and immunopathological features. Although rare, cutaneous vasculitis induced by SARS-CoV-2 and vaccines may provide interesting insights in pathogenesis of these inflammatory processes which may in future be useful to understand the mechanisms underlying cutaneous and systemic vasculitis.