AUTHOR=Ruan Xiaoting , Yang GuangYao , Xia Zhaoxia , Zhang Jiaqing , Gu Xiaoxun , Tan Yuan , Liu Zhenzhen , Luo Lixia 

TITLE=Agreement of Anterior Segment Parameter Measurements With CASIA 2 and IOLMaster 700

JOURNAL=Frontiers in Medicine

VOLUME=Volume 9 - 2022

YEAR=2022

URL=https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2022.777443

DOI=10.3389/fmed.2022.777443

ISSN=2296-858X

ABSTRACT=Purpose 
To compare the difference and agreement of central corneal thickness (CCT), keratometry (K), anterior chamber depth (ACD), aqueous depth (AQD) and lens thickness (LT) measured by CASIA 2 and IOLMaster 700 in cataract patients.
Methods 
A total of 81 cataract patients (81 eyes) scheduled for phacoemulsification in the cataract department of Zhongshan Ophthalmic Center, Sun Yat-sen University were prospectively collected from March to May, 2020, including 43 males and 38 females with an age of (61.5 ±10.6) years. CCT, Anterior Kf, Anterior Ks, Real Kf, Real Ks, ACD, AQD and LT were measured by CASIA 2 and IOLMaster 700 respectively. Paired-t test, intraclass correlation coefficients (ICCs), the 95% limit of agreement (95% LoA) and Bland-Altman plots were used to analyze the difference and agreement of the two devices.
Results 
There was no statistically significant difference in Anterior Ks measurement by the CASIA 2(44.30±1.66mm) and IOLMaster 700. (44.31±1.67mm,P=0.483). The differences between the of CCT, Anterior Kf, Real Kf, Real Ks, ACD, AQD and LT measured by the two instruments were statistically significant (P < 0.001). The ICCs of CCT, Anterior Kf, Anterior Ks, Real Kf, Real Ks, ACD, AQD and LT measurements between the two devices were 0.892, 0.991, 0.991, 0.827, 0.817, 0.937, 0.926 and 0.997, respectively. The 95% LoA between the CASIA 2 and IOLMaster 700 were -30.06 to 0.43μm for CCT,-0.30 to 0.48D for Anterior Kf, -0.46 to 0.43D for Anterior Ks,-1.49 to -0.49D for Real Kf, -1.62 to -0.49D for Real Ks, 0.03 to 0.24 mm for ACD, 0.04 to 0.25 mm for AQD, -0.06 to 0.09mm for LT.
Conclusion 
Anterior Kf , Anterior Ks, ACD, AQD and LT have excellent agreement between the two devices. CCT, Real Kf and Real Ks have moderate agreement between the two devices. It is recommended to use Anterior Kf,  Anterior Ks, ACD, AQD and LT interchangeably between CASIA 2 and IOLMaster 700.