AUTHOR=Fang Yiling , Jing Qi , Cao Silu , Sun Xiaoru , Zhang Hui , Tian Li , Li Cheng 

TITLE=The Effect of Relaxation Therapy on Hypoxia During Intravenous Propofol Anesthesia in Patients With Pre-operative Anxiety: A Prospective Randomized Controlled Trial

JOURNAL=Frontiers in Medicine

VOLUME=Volume 9 - 2022

YEAR=2022

URL=https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2022.797337

DOI=10.3389/fmed.2022.797337

ISSN=2296-858X

ABSTRACT=Background: This study aimed to investigate the effect of relaxation therapy on hypoxia during intravenous anaesthesia with propofol in patients with preoperative anxiety.
Methods: Two-hundred and eighty patients were randomly categorized in the experimental (relaxation therapy group) and control groups. The Spielberger State-Trait Anxiety Inventory (S-STAI) was administered 30 to 60 min preoperatively to assess the patient's current anxiety status and select appropriate patients. Patients in the experimental group received pre-surgical relaxation therapy. The decrease in oxygen saturation during the procedure was recorded for each patient group, and the relevant data were compared between the two groups.
Results: The basic S-STAI scores of the experimental and control groups were 56.88±2.91 and 57.27±3.56, respectively (P = 0.331); the difference was not statistically significant. The incidence of hypoxia in the experimental group during painless artificial abortion (SpO2 <95%, duration greater than 15 s) decreased from 30% to 12.3%.
Conclusion: Relaxation therapy may effectively reduce the incidence of hypoxia during painless artificial abortion by using less dose of propofol. It may help patients relieve their anxiety and improve perioperative safety.