AUTHOR=Wu Chan , Dai Rongping , Chen Youxin , Zhang Xiao , Chen Zhe TITLE=Clinical Features and Surgical Treatment of Subretinal Proliferation in Proliferative Diabetic Retinopathy JOURNAL=Frontiers in Medicine VOLUME=Volume 9 - 2022 YEAR=2022 URL=https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2022.833519 DOI=10.3389/fmed.2022.833519 ISSN=2296-858X ABSTRACT=Purpose: To describe the clinical characteristics, treatments and prognosis of subretinal proliferation (SRP) in proliferative diabetic retinopathy (PDR) patients. Methods: A total of 184 patients (221 eyes) who received vitrectomy for PDR between 2018 and 2021 were retrospectively reviewed. Patients with SRP were further evaluated. The following data were collected from their medical records: demographics, systemic and ophthalmologic findings, and treatment given specifically for SRP. The main outcome measures included the visual acuity, funduscopic examination and final anatomic success. Results: Twelve eyes of 11 patients including 7 females and 4 males with a mean age of 47.64±11.21 years were evaluated. The surgical indication for the patients was mainly tractional retinal detachment (TRD) (100.0%). No retinal break was found preoperatively or intraoperatively. Only one eye (8.3%) had undergone subretinal band removal procedure intraoperatively, and the final anatomical success rate was 100%. Conclusion: SRP in PDR was associated with TRD. The retina could reattach successfully after vitrectomy without removal or transection of SRP in most eyes.