AUTHOR=Yin Xiaochun , Gu Lihong , Zhang Ming , Yin Qin , Xiao Jiangqiang , Wang Yi , Zou Xiaoping , Zhang Feng , Zhuge Yuzheng 

TITLE=Covered TIPS Procedure-Related Major Complications: Incidence, Management and Outcome From a Single Center

JOURNAL=Frontiers in Medicine

VOLUME=Volume 9 - 2022

YEAR=2022

URL=https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2022.834106

DOI=10.3389/fmed.2022.834106

ISSN=2296-858X

ABSTRACT=Background and Objective: Transjugular intrahepatic portosystemic shunt (TIPS) is a well-established procedure for treating complications of portal hypertension. Due to the complexity of anatomy and the difficulty of puncture technique, the procedure itself might brought potential complications, such as puncture failure, bleeding, infection, and death rarely. The aim of the present study is to explore the incidence, management and outcome of TIPS procedure-related major complications using covered stents.
Methods: Patients with TIPS implantation from January 2015 to December 2020 were recruited retrospectively. The major complications after TIPS were screened and analyzed.
Results: Nine hundred and forty-eight patients underwent TIPS procedure with 95.1% (n=902) technical success in our department. TIPS procedure-related major complications occurred in 30 (3.2%) patients, including hemobilia(n=13, 1.37%), hemoperitoneum(n=7, 0.74%), accelerated liver failure (n=6, 0.63%), and rapidly progressive organ failure (n=4, 0.42%). Among them, 8 patients died due to hemobilia(n=1), accelerated liver failure (n=4), and rapidly progressive organ failure (n=3).
Conclusion: The incidence of major complications related to TIPS procedure is relatively low, and part of them could recover through effective medical intervention. In our cohort, the overall incidence is about 3%, which causes 0.84% death. The most fatal complication is organ failure and hemobilia.