AUTHOR=Zhou Fating , Wang Hongxia , Jian Mengyao , Wang Zhiyuan , He Yarong , Duan Haizhen , Gan Lu , Cao Yu 

TITLE=Gray-White Matter Ratio at the Level of the Basal Ganglia as a Predictor of Neurologic Outcomes in Cardiac Arrest Survivors: A Literature Review

JOURNAL=Frontiers in Medicine

VOLUME=Volume 9 - 2022

YEAR=2022

URL=https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2022.847089

DOI=10.3389/fmed.2022.847089

ISSN=2296-858X

ABSTRACT=Loss of gray-white matter discrimination is the early image feature of cranial computer tomography in cardiac arrest survivors, and it has been also regarded as a novel predictor for evaluating the neurologic outcome. As displaying clearly in computer tomography and sensitive to hypoxia, gray-white matter ratio at basal ganglia (GWR-BG) region was frequently detected to assess the neurologic outcome by several studies. The specificity of GWR-BG is 72.4% to 100%, while the sensitivity is significantly different. Here we review the mechanism of cerebral edema following cardiac arrest, demonstrate the determination procedure of GWR-BG, summarize the related research about GWR-BG predicting neurologic outcome of cardiac arrest survivors, and discuss those factors associated with predicting accuracy. Finally, we describe the effective measurements to increase the sensitivity of GWR-BG in predicting neurologic outcome.