AUTHOR=Xue Yi , Zhou Jie , Xu Bei-Ni , Li Yue , Bao Wu , Cheng Xia Lin , He Yan , Xu Chun Peng , Ren Jun , Zheng Ya rong , Jia Chi Yu TITLE=Global Burden of Bacterial Skin Diseases: A Systematic Analysis Combined With Sociodemographic Index, 1990–2019 JOURNAL=Frontiers in Medicine VOLUME=Volume 9 - 2022 YEAR=2022 URL=https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2022.861115 DOI=10.3389/fmed.2022.861115 ISSN=2296-858X ABSTRACT=Background: The latest incidence and disability-adjusted life-years (DALYs) of major bacterial skin diseases(BSD) and their relationship with socioeconomic are not readily available. Objective: Describe the global age-standardized incidence and DALYs of BSD and analyze their relationship with socioeconomic. Methods: All data were obtained from Global Burden of Disease (GBD) 2019 database. The correlation between BSD and socioeconomic development status was analyzed. Results: The age-standardized incidence and age-standardized DALYs rate of BSD are: 169.72 million [165.28-175.44] and 0.41million [0.33-0.48]. Of the two main BSD, pyoderma cause significantly much heavier burden than cellulitis. The change of age-standardized incidence (7.38% [7.06-7.67]) and DALYs (-10.27% [-25.65 to 25.45]) rate of BSD presented an upward or downward trend from 1990 to 2019. In 2019, the highest burden was in the low-middle SDI area while the area with the lowest burden was recorded in the high-middle SDI area. Limitations: GBD 2019 data of BSD are derived from estimation and mathematical modelling. Conclusion: The burden of BSD is related to socioeconomic development status. The results based on GBD2019 data may benefit policymakers in guiding priority-setting decisions for the global burden of BSD.