AUTHOR=Piquin Gwendoline , Chapron Thibaut , Abdelmassih Youssef , Martin Gilles , Edelson Catherine , Caputo Georges , Metge Florence 

TITLE=Coats disease in female population: A comparison of clinical presentation and outcomes

JOURNAL=Frontiers in Medicine

VOLUME=Volume 9 - 2022

YEAR=2022

URL=https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2022.879110

DOI=10.3389/fmed.2022.879110

ISSN=2296-858X

ABSTRACT=Purpose: To compare clinical characteristics at presentation and outcomes of Coats’ disease between females and males.
Methods: In this retrospective, consecutive case series we included all children diagnosed with Coats’ disease in a single tertiary referral center. Initial clinical presentation, treatment and outcomes were collected. 
Results: A total of 158 children were included, of whom 29 (18.3%) were females and 11 (6.9%) had bilateral involvement. Age at diagnosis and disease stage were similar between females and males. Females tended to have a worse visual acuity at diagnosis (p = 0.05) and more bilateral involvement (p < .001). Visual and anatomical outcomes after treatment were similar between genders. 
Conclusion: Female patients with Coats’ disease have more bilateral involvement and tended to have worse visual acuity at presentation. Clinical presentation and outcomes seem to be similar between genders.