AUTHOR=Lee Irene Tai-Lin , Juang Sin-Ei , Chen Steven T. , Ko Christine , Ma Kevin Sheng-Kai 

TITLE=Sentiment analysis of tweets on alopecia areata, hidradenitis suppurativa, and psoriasis: Revealing the patient experience

JOURNAL=Frontiers in Medicine

VOLUME=Volume 9 - 2022

YEAR=2022

URL=https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2022.996378

DOI=10.3389/fmed.2022.996378

ISSN=2296-858X

ABSTRACT=Abstract
Background
Psychiatric comorbidities can commonly occur in patients suffering from chronic dermatologic disorders. Sentiment analysis of disease-related tweets helps identify patients’ experiences of skin disease. 
Objective
To analyze the expressed sentiments in tweets related to alopecia areata (AA), hidradenitis suppurativa (HS), and psoriasis (PsO) in comparison to fibromyalgia (FM). 
Methods
This is a cross-sectional analysis of Twitter users’ expressed sentiment on AA, HS, PsO, and FM. Tweets related to the diseases of interest were identified with keywords and hashtags for one month (April 2022) using the Twitter standard application programming interface (API). Text, account types, and numbers of retweets and likes were collected. The sentiment analysis was performed by the R ‘tidytext’ package using the AFINN lexicon. 
Results
A total of 1,505 tweets were randomly extracted, of which 243 (16.15%) referred to AA, 186 (12.36%) to HS, 510 (33.89%) to PsO, and 566 (37.61%) to FM. The mean sentiment score was -0.239 ± 2.90. AA, HS, and PsO had similar sentiment scores (p = 0.482) and the average was significantly more positive than FM (p < 0.0001). Words reflecting patients’ psychological states were found differently in different diseases. ‘Anxiety’ was associated with AA and FM posts but not with HS and PsO; while ‘crying’ was frequently used in HS posts. 
Conclusions
The use of Twitter sentiment analysis is a promising method to document patients’ experience of skin disease. This technique has the potential to improve patient care, strategize public health policies, and direct organizational campaigns.