AUTHOR=Albert E. , Walsemann T. , Behrends J. , Jappe U. 

TITLE=Lipid transfer protein syndrome in a Northern European patient: An unusual case report

JOURNAL=Frontiers in Medicine

VOLUME=Volume 10 - 2023

YEAR=2023

URL=https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2023.1049477

DOI=10.3389/fmed.2023.1049477

ISSN=2296-858X

ABSTRACT=Non-specific lipid transfer proteins (nsLTPs) as the primary sensitizer in plant-food allergic patients used to be seen primarily in the Mediterranean area. However, more recently increasing numbers of clinically relevant sensitizations are being reported in Northern Europe. We herein report an unusual case of a woman, who developed an anaphylactic reaction during a meal including a variety of different foods ranging from fruits and nuts to oats, wheat, and salmon. Allergy diagnostics showed no Bet v1 sensitization but an nsLTP-mediated food allergy. Despite the much more prominent birch food syndrome in Central and Northern Europe, LTPs should be considered as disease-causing agents, especially for patients developing severe reactions after consuming LTP-containing foods.