AUTHOR=Zhang He , Ni Yuanyuan , Ji Hangyu , Liu Hongliang , Liu Shaoneng 

TITLE=Research trends of omics in ulcerative colitis: A bibliometric analysis

JOURNAL=Frontiers in Medicine

VOLUME=Volume 10 - 2023

YEAR=2023

URL=https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2023.1115240

DOI=10.3389/fmed.2023.1115240

ISSN=2296-858X

ABSTRACT=Background: Omics has emerged as a promising biological science to shed light on the etiology, pathogenesis and treatment of Ulcerative colitis (UC). At present, although research on omics of UC has drawn global attention, there is still lack of bibliometric analysis in this field. This study aimed to access the trends and hotspots of omics in UC research.
Method: Publications related to omics in UC from January 1, 2000 to October 15, 2022 were retrieved from the Web of Science Core Collection database. VOSviewer, CiteSpace and the online bibliometric analysis platform “bibliometrix” were adopted to extract and visualize information.
Results: A total of 385 publications were finally included and the annual number of publications was fluctuated. The trend in publications increased rapidly after 2019. The Untied Stated showed its dominant position in number of publications, total citations and international collaborations. The top five research organizations for publications on the research of omic in UC were Harvard Medical School, Icahn School of Medicine at Mount Sinai, Karolinska Institutet, Brigham & womens hospital and Massachusetts General Hospital. Ashwin Ananthakrishnan from Massachusetts General Hospital was the most productive author and Séverine Vermeire from Catholic University of Leuven was co-cited most often. Inflammatory Bowel Disease was the most popular and co-cited journal in this field. The reference with citation bursts and trend topic showed that “ulcerative colitis”, “inflammatory bowel disease”, “microbiome”, “transcriptomics”, “genomics”, “metabolomics”, “proteomics”, “dysbiosis”, “biomarkers”, “loci” and “therapy” are currently research hotspots.
Conclusion: Our study presents several important insights into the research trends and developments in the field of omics in UC, which will provide key information for further research.