AUTHOR=Vali Saaliha , Jones Benjamin P. , Sheikh Sairah , Saso Srdjan , Quiroga Isabel , Smith J. Richard TITLE=Attitudes, knowledge, and perceptions among women toward uterus transplantation and donation in the United Kingdom JOURNAL=Frontiers in Medicine VOLUME=Volume 10 - 2023 YEAR=2023 URL=https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2023.1223228 DOI=10.3389/fmed.2023.1223228 ISSN=2296-858X ABSTRACT=Objective To assess the motivations and perceptions of the general public in the UK toward donating their uterus for Uterus Transplantation after death (UTx). Design A cross sectional study Setting A 32-item electronic questionnaire. Population 159 females over the age of 16 living in the UK, consented and took part in the study. Main Outcome Measures The motivations and perceptions towards UTx amongst the general public including the willingness to donate and barriers preventing donation. Results 159 women completed the questionnaire. The majority had never heard of UTx (n=107, 71%) and most were not aware the uterus could be donated after death (n=130, 92%). 43% of the cohort were willing to donate their uterus after death (n=57). 8% stated they wished to donate their organs but not their uterus (n=10). 30% of women (n=42) believed the child born following UTx would have genetic links to the donor. Over half of the respondents (n=65, 51%) strongly agreed or agreed they would feel joy in the knowledge that donation would lead to bringing a new life into the world. A quarter of respondents strongly agreed or agreed (n=45, 25%) that the use of their uterus by another woman would feel like an extension of life. Conclusions The findings indicate a favourable opinion towards UTx and a positive attitude towards donation of the uterus after death amongst the general public in the UK. The findings also highlight the need for education around UTx now this therapeutic option is available.