AUTHOR=Song Xi , Zhang Chunying , Zhang Saisai , He Mansha 

TITLE=Therapeutic efficacy of optimal pulse technology in the treatment of chalazions

JOURNAL=Frontiers in Medicine

VOLUME=Volume 10 - 2023

YEAR=2023

URL=https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2023.1286159

DOI=10.3389/fmed.2023.1286159

ISSN=2296-858X

ABSTRACT=Introduction: To evaluate the efficacy of optimized pulse technology in treating chalazia.Methods: Prospective before-after study. All patients received two sessions of optimal pulse technology(OPT) with an interval of one week. The first visit was before treatment and the patients underwent two treatment sessions with a 1-week interval.The non-invasive tear breakup time (NIBUT), corneal fluorescein staining (CFS) score, Schirmer's test I without anesthesia, conjunctival hyperemia, and meibomian gland area were compared before and after treatment, and the related factors of curative effect were analyzed.Results: 23 patients (23 eyes) with chalaziawere included. All patients received two sessions of OPT treatment at one-week intervals. Following the first OPT treatment, a reduction in the chalazion size was observed in seventeen patients(73.91%). One patient was completely cured, and one patient had an increase in the diameter of the chalazion. The meibomian gland area increased significantly compared to before treatment (P=0.023). Compared with baseline, the conjunctival congestion and ST decreased, NIBUT increased, and there was no statistical difference. After the second treatment, the chalazion size decreased in twenty-one cases, and three patients were cured. A significant increase in the meibomian gland area compared with the baseline area(P＜0.001). Additionally, conjunctival congestion decreased significantly. After two sessions, the Schirmer test exhibited a decrease, and NIBUT increased, although these changes did not reach statistical significance. The curative effect was unrelated to sex, age, first onset, single disease, and other factors.Conclusion: After treatment, the diameter of chalazions was reduced in 91.3% of the patients, and the area of the meibomian gland was significantly increased compared with that before treatment,whitch suggested that two OPT treatments at an interval of one week can improve the signs of adult patients in the non-acute infectious stage with chalazia..