AUTHOR=Yu Xiao , Li Zhao , Yang Xinbo , Wang Xiaopei , Nan Di , Lu Wanhong , Lv Jing , Ma Ying 

TITLE=Microbacterium spp. peritonitis in patients undergoing peritoneal dialysis: a single-center experience and literature review

JOURNAL=Frontiers in Medicine

VOLUME=Volume 10 - 2023

YEAR=2023

URL=https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2023.1297296

DOI=10.3389/fmed.2023.1297296

ISSN=2296-858X

ABSTRACT=INTRODUCTION: Peritoneal dialysis-related peritonitis (PDRP) caused by Microbacterium spp. is very rare, with only 9 cases reported to date. In this study, we report the treatment experiences of 7 patients at our peritoneal dialysis center. 
METHODS: We retrospectively collected clinical characteristics and antibiotic management of all 7 episodes of PDRP caused by Microbacterium spp. in 7 patients from at our center over 4 years, and reviewed the documented Microbacterium spp. PDRP in the literature. 
RESULTS: Empiric antibiotic therapy was initiated as soon as possible, and consisted of intraperitoneal (IP) gentamicin in combination with vancomycin. After up to 5 days, gentamicin was changed to meropenem if the treatment was not effective. The intended course of antibiotic treatment was 21-day. Totally, 6 episodes were cured (85.7%), which was higher than reported. 
CONCLUSION: The 21-day antibiotic therapy program by combining vancomycin and meropenem may benefit the management of Microbacterium spp. PDRP.