AUTHOR=Fu Wei , Liu Xiaoqing , Guan Lili , Lin Zhimin , He Zhenfeng , Niu Jianyi , Huang Qiaoyun , Liu Qi , Chen Rongchang 

TITLE=Prognostic analysis of high-flow nasal cannula therapy and non-invasive ventilation in mild to moderate hypoxemia patients and construction of a machine learning model for 48-h intubation prediction—a retrospective analysis of the MIMIC database

JOURNAL=Frontiers in Medicine

VOLUME=Volume 11 - 2024

YEAR=2024

URL=https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2024.1213169

DOI=10.3389/fmed.2024.1213169

ISSN=2296-858X

ABSTRACT=Background：To investigate the clinical outcome between high flow nasal cannula (HFNC) and non-invasive ventilation (NIV) therapy in mild to moderate hypoxemic patients on the first ICU day, and to develop a predictive model of 48-hour intubation. 
Methods: The study included adult patients from the MIMIC III and IV databases who first initiated HFNC or NIV therapy due to mild to moderate hypoxemia (100