AUTHOR=Tsige Abate Wondesen , Beyene Dessale Abate , Wondmkun Yehualashet Teshome , Endalifer Bedilu Linger , Habteweld Habtemariam Alekaw , Gebretadik Fissha Assegidew , Gebeyehu Aregahegn Adafir , Azene Belayneh Abebaw , Alamneh Misganaw Abebaw , Tesfaye Daniel Zebene , Fered Misganaw Aynalem , Girma Mandefro Teje , Mekonen Melkamu Belayneh , Dessie Tigist Yazezew , Ayele Siraye Genzeb 

TITLE=Assessment of the appropriateness of stress ulcer prophylaxis use and its determinants among admitted surgical patients at Debre Berhan University Hakim Gizaw Hospital, Ethiopia. A hospital-based cross-sectional study

JOURNAL=Frontiers in Medicine

VOLUME=Volume 11 - 2024

YEAR=2024

URL=https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2024.1345144

DOI=10.3389/fmed.2024.1345144

ISSN=2296-858X

ABSTRACT=Introduction: Pharmacological stress ulcer prophylaxis (SUP) has been recommended for many years to reduce the risk of clinically significant upper gastrointestinal (GI) bleeding caused by stress ulcers. Stress-related ulcer bleeding in surgical patients significantly increases morbidity and mortality. Therefore, preventing stress-induced hemorrhage is the most appropriate measure for patients who are at increased risk. However, the inappropriate use of SUP has increased in recent years, and its use in Ethiopian surgical patients has not been well studied.