AUTHOR=Ye Hongfei , Wu Mengxiao , Sun Wan , Lyu Jiao , Xu Yu , Fei Ping , Peng Jie , Jin Haiying , Zhao Peiquan TITLE=Clinical observation of a modified technique for intrascleral fixation of flanged three-piece foldable intraocular lenses through a Hoffman pocket JOURNAL=Frontiers in Medicine VOLUME=Volume 11 - 2024 YEAR=2024 URL=https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2024.1382100 DOI=10.3389/fmed.2024.1382100 ISSN=2296-858X ABSTRACT=Purpose: To present the observation outcomes of a new technique for intrascleral fixation of a flanged three-piece foldable intraocular lens (IOL) without a conjunctival incision.We retrospectively reviewed a consecutive series of 12 eyes of 12 patients who underwent scleral IOL fixation using this technique.The follow-up period ranged 3 to 12 months. There was a significant improvement in bestcorrected visual acuity, from 0.8 (1.6) logarithm of the minimum angle of resolution (logMAR) preoperatively to 0.45 (0.8) logMAR at the final postoperative follow-up (P=0.012). Notable complications included one case of pupillary IOL capture and increased intraocular pressure.Our novel technique is a viable solution for managing secondary IOL fixation, enabling the use of a wider variety of IOLs and simplifying the repositioning process for dislocated three-piece IOLs. This approach has the potential to lower complication rates and enhance patient recovery.