AUTHOR=Ma Jinxiu , Zhao Gang , Bi Mingchao , Dong Xiaoxiao , Sun Jian , Wang Xiaozhen TITLE=Malignant breast adenomyoepithelioma: case report and literature review JOURNAL=Frontiers in Medicine VOLUME=Volume 11 - 2024 YEAR=2025 URL=https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2024.1525050 DOI=10.3389/fmed.2024.1525050 ISSN=2296-858X ABSTRACT=Malignant adenomyoepithelioma (MAME) of the breast is a rare tumor with both benign and malignant features. We report a case of a 67-year-old woman who presented with a mass in the outer quadrant of the right breast, detected during a routine check-up. The mass was classified as BI-RADS 3. After minimally invasive excision, pathology confirmed low-grade malignant adenomyoepithelioma. The patient then underwent total mastectomy and sentinel lymph node biopsy (SLNB). At two years of follow-up, there was no recurrence or metastasis. This case highlights the rarity of MAME and the importance of early diagnosis and complete excision.