AUTHOR=Jung Carolin , Stueber Thomas , Mirus Martin , Heubner Lars , Spieth Peter Markus TITLE=Anticoagulation in venovenous extracorporeal membrane oxygenation JOURNAL=Frontiers in Medicine VOLUME=Volume 12 - 2025 YEAR=2025 URL=https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2025.1530411 DOI=10.3389/fmed.2025.1530411 ISSN=2296-858X ABSTRACT=Venovenous extracorporeal membrane oxygenation (VV-ECMO) is a lifesaving therapy in severe acute respiratory distress syndrome (ARDS). Unfortunately, bleeding and thrombotic complications occur regularly due to coagulation disorders associated with the device, the underlying disease, and the anticoagulation management. To facilitate a personalized approach to hemostasis in individuals receiving ECMO support, it is essential to assess the coagulative state of the patient while simultaneously taking into account the underlying medical condition and administered therapies.