AUTHOR=An Xiao-Ling , Zhang Jun , Yun Xiao-Chun , Lei Xiao-Hui , Zhao Jing , Yang Xiao-Hua , Liu Mei-Mei 

TITLE=Perspectives in transvaginal sonography for the diagnosis of adenomyosis

JOURNAL=Frontiers in Medicine

VOLUME=Volume 12 - 2025

YEAR=2025

URL=https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2025.1533648

DOI=10.3389/fmed.2025.1533648

ISSN=2296-858X

ABSTRACT=Adenomyosis is a common gynecological condition affecting women of reproductive age, posing significant diagnostic challenges due to its diverse clinical presentations. This extended opinion study critically reviews the diagnostic methods for adenomyosis, with a focus on transvaginal sonography (TVS), a widely used non-invasive imaging technique. The study evaluates the effectiveness, limitations, and clinical applicability of TVS, while exploring the role of histopathological confirmation when non-invasive methods are insufficient. Advancements in TVS, including three-dimensional ultrasound and color Doppler, have enhanced diagnostic precision, particularly in assessing uterine morphology and blood flow. Additionally, artificial intelligence integration offers potential to further optimize diagnostic accuracy and efficiency. While histopathological examination remains the gold standard, its use is often impractical in patients who do not undergo hysterectomy. This study provides a comprehensive overview of the current status of TVS in diagnosing adenomyosis, analyzing its accuracy, strengths, and limitations across diverse patient populations. Results suggest that TVS is a reliable diagnostic tool, though its accuracy improves when combined with magnetic resonance imaging, especially in complex cases. Ongoing research is needed to refine TVS capabilities and identify non-invasive alternatives to histopathological confirmation, improving accessibility and diagnostic efficiency.