AUTHOR=Giorgetti Claudia , Contissa Giuseppe , Basile Giuseppe 

TITLE=Healthcare AI, explainability, and the human-machine relationship: a (not so) novel practical challenge

JOURNAL=Frontiers in Medicine

VOLUME=Volume 12 - 2025

YEAR=2025

URL=https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2025.1545409

DOI=10.3389/fmed.2025.1545409

ISSN=2296-858X

ABSTRACT=This paper focuses on the lack of explainability that afflicts machine-learning-based AI systems applied in the field of healthcare. After a brief introduction to the topic, from both a technical and legal point of view, this work aims to assess the main consequences that the lack of explainability has on the human-machine relationship in clinical care, through a practical perspective. It then questions whether explainability is truly an objective worth seeking and, if so, to what extent, taking into account the current possible solutions.