AUTHOR=Loza-González Víctor Manuel , Martínez-Jiménez Mario Aurelio , Novoa-Moreno Ana Lorena , Ramírez-GarcíaLuna José Luis , Ortiz-Dosal Alejandra , Kolosovas-Machuca Eleazar Samuel TITLE=Diabetic foot ulcer healing with polylactic acid membrane assessed by thermographic imaging: a case report JOURNAL=Frontiers in Medicine VOLUME=Volume 12 - 2025 YEAR=2025 URL=https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2025.1568144 DOI=10.3389/fmed.2025.1568144 ISSN=2296-858X ABSTRACT=Diabetic foot ulcers reduce patient’s quality of life and increase treatment costs, evaluating this condition is promising. We report the clinical progression of an elderly patient who developed a diabetic foot ulcer following minor trauma. She was treated for over 2 months until her condition progressed to Grade 4 on the Wagner Classification of Diabetic Foot. A Serial infrared thermography was performed. The treatment plan included antibiotics and a polylactic acid membrane until complete ulcer remission. Thermographic imaging showed a quantitative reduction of the temperature differences between the affected and contralateral foot from an initial ΔT: −4.6°C ± 2.4, progressing to ΔT: −1.7°C ± 1.6 at 12 weeks, and a temperature reduction from the proximal third tibial area with ΔT: −1.7°C ± 0.6, with a change to ΔT 0.8°C ± 0.4 at 12 weeks near the metatarsal bone region. This article underscores the use of infrared thermography to give physicians feedback on ulcer healing progression phases and treatment effectiveness.