AUTHOR=Cao Ximei , Li Jiangtao TITLE=Snare-assisted submucosal tunneling for resection of esophageal schwannomas: Case Report JOURNAL=Frontiers in Medicine VOLUME=Volume 12 - 2025 YEAR=2025 URL=https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2025.1580999 DOI=10.3389/fmed.2025.1580999 ISSN=2296-858X ABSTRACT=Esophageal schwannoma is a rare type of esophageal tumor that presents significant challenges in resection, particularly when large and irregularly shaped. This case report highlights the successful removal of a large esophageal schwannoma using a novel technique that combines submucosal tunneling endoscopic resection (STER) with modified snare-assisted external traction. A 68-year-old male with dysphagia was diagnosed with a 35 mm × 20 mm × 15 mm esophageal schwannoma. Due to the tumor’s size and consistency, traditional resection methods proved difficult. The snare-assisted traction technique, applied within the submucosal tunnel, provided optimal tension and improved visualization, enabling en bloc resection. The patient recovered well postoperatively, and follow-up endoscopy confirmed complete healing. This novel traction technique is safe and effective for the resection of large esophageal submucosal tumors (SMTs), offering enhanced procedural efficiency and better outcomes in complex cases. However, the clinical utility of this technique requires confirmation through prospective studies with adequate sample sizes and long-term outcome assessments.