AUTHOR=Liu Jinguo , Xu Jing , Wang Li , Gu Xiaojiang , Zhang Xuesong , Zhang Zhou , Zhang Chi , Yu Liangliang TITLE=Case Report: A novel strategy of endoscopic full-thickness resection: single traction combined with pre-clamping JOURNAL=Frontiers in Medicine VOLUME=Volume 12 - 2025 YEAR=2025 URL=https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2025.1581544 DOI=10.3389/fmed.2025.1581544 ISSN=2296-858X ABSTRACT=Endoscopic full-thickness resection (EFTR) is an effective, economical, and minimally invasive technique for submucosal tumors (SMTs). However, technical complexity and prolonged operative time remain significant limitations. This study introduces a refined EFTR strategy termed “single traction combined with pre-clamping” in a cohort of 10 patients. The proposed technique demonstrates reduced procedural duration, technical difficulty, and intraoperative risks compared to the conventional approach.