AUTHOR=Lu Juntao , Qiao Yuqi , Wang Tianrong , Cao Zhijun 

TITLE=Case Report: Crohn’s disease with coexisting mesenteric schwannoma

JOURNAL=Frontiers in Medicine

VOLUME=Volume 12 - 2025

YEAR=2025

URL=https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2025.1621976

DOI=10.3389/fmed.2025.1621976

ISSN=2296-858X

ABSTRACT=This case report discusses a rare instance of Crohn’s disease coexisting with a mesenteric schwannoma in a 22-year-old man. The patient initially presented with painful defecation and recurrent fever. Diagnostic procedures, including MRI, CTE, and FDG-PET/CT, revealed signs consistent with Crohn’s disease and an enlarged abdominal “lymph node” suspected to be a schwannoma. Despite exclusive enteral nutrition, the nodule persisted, complicating further treatment. Surgical resection confirmed the diagnosis of schwannoma. This report highlights the diagnostic challenges and treatment complexities when Crohn’s disease coexists with rare tumors such as schwannomas.