AUTHOR=Li Yiwen , Bai Caiyun , Ma Yuye , Fan Zhimin , Wang Xiaozhen , Qu Fengjiang 

TITLE=Diagnostic challenges in breast carcinosarcoma: a case report of a rare and aggressive tumor

JOURNAL=Frontiers in Medicine

VOLUME=Volume 12 - 2025

YEAR=2025

URL=https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2025.1633085

DOI=10.3389/fmed.2025.1633085

ISSN=2296-858X

ABSTRACT=Background and objectivesBreast carcinosarcoma is rare. This article reports a case of diagnosis and treatment to enhance clinicians’ understanding and experience in managing this disease.MethodsA 44-year-old patient with breast carcinosarcoma treated at the Breast Surgery Department of the First Hospital of Jilin University is reported, highlighting the challenges in the diagnostic process.ResultsPostoperative pathology confirmed carcinosarcoma. The patient underwent mastectomy, chemotherapy, and radiotherapy, with no recurrence during follow-up.ConclusionThe nonspecific clinical manifestations of breast carcinosarcoma make preoperative diagnosis challenging, requiring a comprehensive diagnostic approach.