AUTHOR=Yin Hui , Shao Yingchun , Sun Fusheng 

TITLE=The latest research progress on the clinical application of nemonoxacin

JOURNAL=Frontiers in Medicine

VOLUME=Volume 12 - 2025

YEAR=2025

URL=https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2025.1671640

DOI=10.3389/fmed.2025.1671640

ISSN=2296-858X

ABSTRACT=Nemonoxacin is a novel non-fluorinated quinolone antibacterial agent, characterized by a broad antibacterial spectrum, strong antibacterial activity, low protein binding rate, high oral bioavailability, and extensive tissue distribution. Its unique pharmacological properties confer high clinical application value. In the context of bacterial resistance, this article aims to provide a comprehensive review of nemonoxacin’s antibacterial activity, immunomodulatory effects, and its application in infectious diseases as well as in patients with hepatic or renal insufficiency, with the goal of offering more drug options for clinical treatment and providing a reference for future clinical research and widespread application.