AUTHOR=Park Hyunsuk , Jeong Hyein , Kim Kyeong Han , Yang Seung Jeong , Roh Stella TITLE=Management of symptoms of suspected adenomyosis uteri using herbal medicine modified Bojungikgi-tang: a case report with ultrasound monitoring JOURNAL=Frontiers in Medicine VOLUME=Volume 12 - 2025 YEAR=2025 URL=https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2025.1679449 DOI=10.3389/fmed.2025.1679449 ISSN=2296-858X ABSTRACT=IntroductionAdenomyosis is a chronic gynecological disorder characterized by the infiltration of ectopic endometrial tissue into the myometrium, affecting approximately 20–35% of women of reproductive age. Although hormonal therapy and surgery are common treatments, their side effects and impact on fertility highlight the need for alternative approaches. Recently, integrative medicine, including traditional Korean medicine, has gained attention. However, well-documented long-term case studies using objective imaging are limited.MethodsA 40-year-old woman with severe adenomyosis symptoms unresponsive to conventional therapies received long-term herbal medicine based on modified Bojungikgi-tang, with regular ultrasound monitoring and clinical assessments over 12 months.ResultsAfter treatment, menstrual pain decreased from a numeric rating scale score of 7–8 to 1–2, hemoglobin normalized, and ultrasonography revealed reduced adenomyosis and improved uterine structure. The patient’s quality of life improved markedly with no adverse effects.ConclusionThis case suggests that herbal medicine may be a safe and effective option for managing adenomyosis, supporting further research into integrative treatment strategies.