AUTHOR=Wang Mingyu , Li Luhan , Feng Min , Liu Zhuo 

TITLE=Advances in artificial intelligence applications for the management of chronic obstructive pulmonary disease

JOURNAL=Frontiers in Medicine

VOLUME=Volume 12 - 2025

YEAR=2025

URL=https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2025.1685254

DOI=10.3389/fmed.2025.1685254

ISSN=2296-858X

ABSTRACT=Chronic obstructive pulmonary disease (COPD), characterized by high incidence and mortality rates, is a chronic respiratory disorder that places a substantial burden on healthcare systems. Artificial Intelligence (AI), with its deep integration into the medical field, particularly through its core branches—Machine Learning (ML) and Deep Learning (DL)—has demonstrated significant potential in the intervention and management of COPD. From early risk prediction based on multimodal data to the enhancement of precise diagnosis and treatment through radiomics and clinical decision support systems, and further to the dynamic assessment of acute exacerbation and comorbidity risks via machine learning models, AI has, in combination with bioinformatics and multi-omics analysis, established a novel intelligent management framework that spans the entire disease continuum. This framework offers innovative, individualized solutions aimed at alleviating the burden on healthcare systems. This article reviews the technical applications and clinical value of AI in the diagnosis, prevention, treatment, and prognosis of COPD, discusses current challenges, and outlines future development directions to provide insights for clinical practice and research.